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Occupation & Cancer Basic Description In the early 1980s, occupational exposure to carcinogenic ( cancer - causing) substances was estimated to account for about 4% of all cancers in the United States; however, occupational exposure to car- cinogens has been greatly reduced since that time. While it is difficult to obtain reliable estimates of both the percentage of cancers caused by occupational exposure to carcinogens and the number of workers exposed, cancers caused by occupational exposure are now likely to be considerably less than the 4% estimates of 2 decades ago. Nevertheless, it is known that certain chemicals (e.g., benzene, nickel compounds, vinyl chloride), dusts (e.g., leather or wood dusts, silica, asbestos), pesticides (e.g., ethylene oxide, chlorophenoxyl herbicides), radiation (e.g., sunlight, radon gas, industrial, medical, or other expo- sure ...

UV Radiation & Cancer Basic Description Ultraviolet (UV) radiation from sunlight can damage DNA, the criti- cal genetic material in every cell of every person. When damaged by UV radiation from sunlight or artificial light sources such as sun lamps and tanning booths, DNA loses its power to control how and when cells grow and divide. Sometimes, this DNA damage leads to the formation of skin cancer . Strength of Evidence There are two types of skin cancer : non-melanoma and melanoma. Non-melanoma is the most common form of skin cancer . It occurs in either basal or squamous skin cells; these cells are located at the base of the outer layer of skin. Melanoma skin cancers are much less com- mon and develop from melanocytes, the cells that produce skin color. UV radiation is the primary cause of skin cancer . People who live in areas with year-round ...

Skin Cancer Basic Description Skin cancer is the most common of all cancers . Fortunately, most skin cancers are slow-growing, easy to recognize, and relatively easy to treat when detected early. Skin cancers may be classified as non- melanoma and melanoma. Most skin cancers are classified as non-melanoma, meaning they occur in either basal cells or squamous cells. These cells are located at the base of the outer layer of the skin or cover the internal and external surfaces of the body. Most non-melanoma skin cancers develop on sun-exposed areas of the body, like the face, ear, neck, lips, and the backs of the hands. Depending on the type, they can be fast or slow growing, but they rarely spread to other parts of the body. Melanoma skin cancers develop from melanocytes, the cells that pro- duce our skin color. Melanoma is almost always curable when it is ...

Tobacco & Cancer Basic Description Tobacco use, the most preventable cause of death in our society, accounts for at least 30% of all cancer deaths. In 1999, an estimated 47 million adults were current smokers in the United States. About half of those who continue to smoke will die prematurely from smok- ing. The best way to avoid getting cancer is not to start using tobacco or to quit using it. Strength of Evidence Strong evidence over the years has found a clear cause-and-effect relationship between the use of tobacco and several different types of cancer . Cancers Affected Smoking causes nearly 87% of all lung cancers . Lung cancer mortality rates are more than 15 times higher for current smokers compared with people who have never smoked. Tobacco use is also associated with cancer of the cervix, mouth, pharynx, larynx, esophagus, ...

Cervical Cancer Basic Description Cervical cancer begins in the lining of the cervix. The cervix is the lower part of the womb, or uterus, which connects the body of the uterus (where a fetus grows) to the vagina or birth canal. Cancer of the cervix forms slowly. First, some normal cells change to pre- cancer and then to cancer . These changes can take a number of years, although sometimes it happens more quickly. For most women, pre- cancerous changes go away without any treatment. For others, these cells need to be treated to keep them from changing into cancer . Signs and symptoms of cervical cancer may include unusual vaginal bleeding, spotting, or discharge, and pain or bleeding during sex. However, cervical pre- cancers and early cervical cancer often have no signs or symptoms, so it is very important for women to have regular Pap tests. Opportunities ...

Oral Cancer Basic Description Cancer can affect any part of the oral cavity, including the lips, tongue, mouth, and throat. There are two kinds of oral cancers : oral cavity cancer , which starts in the mouth, and oropharyngeal cancer , which develops in the part of the throat just behind the mouth (called the oropharynx). The most common symptom of oral cancer is a sore in the mouth that bleeds easily and does not heal. Another common sign of oral cancer is pain in the mouth that does not go away. Other signs and symptoms include: • A lump or thickening in the cheek; • A white or red patch on the gums, tongue, tonsil, or lining of the mouth; and • A sore throat or a feeling that something is caught in the throat. Difficulties in chewing, swallowing, or moving the tongue or jaw are often late symptoms of oral cancer ...

Esophageal Cancer Basic Description The esophagus is the muscular tube that connects the throat to the stomach and allows food to enter the stomach for digestion. Cancer of the esophagus, also called esophageal cancer , can occur anywhere along the lining of the tube. It is relatively uncommon in the United States, accounting for about 1% of total diagnosed cancers . Symptoms of esophageal cancer generally do not appear until the dis- ease has advanced. As the tumor grows, the most common symptom is difficulty swallowing. Cancer of the esophagus can also cause chest pain or burning and frequent choking on food. Because of these prob- lems, weight loss is common. Signs of more advanced cancer include pain while swallowing, hoarseness, hiccups, pneumonia, and high cal- cium levels. However, these symptoms can be caused by other less serious health problems as well. ...

Endometrial Cancer Basic Description Endometrial cancer begins in the endometrium, which is the inner lining of the uterus, or womb. It is the most common cancer of the female reproductive organs in the United States. Symptoms of endometrial cancer include abnormal postmenopausal vaginal bleeding, spotting, or other discharge; pelvic pain and/or mass; and weight loss (usually in later stages of the disease). Opportunities Prevention Although most cases of endometrial cancer cannot be prevented, lower risk of developing this cancer is associated with: • Using oral contraceptives. The risk is lowest in women who take oral contraceptives for a long time, and this protection continues for at least 10 years after a woman stops taking them. • Obtaining proper and timely treatment for pre-cancerous disorders of the endometrium. ...

Physical Activity & Cancer Basic Description Research shows that moderate physical activity for at least 30 min- utes or more a day protects against some cancers ; increasing evi- dence suggests that 45 minutes or more of moderate to vigorous activity on 5 or more days per week may further reduce the risk of breast and colon cancers . Regular physical activity protects against cancer in a variety of ways. Activity can help reduce overweight and obesity, which are associated with increased risk for cancers of the colon, prostate, and breast (among postmenopausal women). For breast cancer , in addition to its role in controlling weight, activity may act through effects on hormone levels. For colon cancer , physi- cal activity stimulates movement through the bowel, thus reducing the length of time the bowel lining is exposed to potential carcino- gens. Maintaining ...

Colorectal Cancer Basic Description Colorectal cancer is the third most common cancer in both men and women. It begins in either the colon or the rectum, which are both part of the digestive or gastrointestinal system, where food is processed. Warning signs for colorectal cancer include rectal bleed- ing, blood in the stool, or a change in bowel habits. These are also warning signs for other, less serious illnesses, so if they appear they should be discussed with a physician. Opportunities Prevention Even though the exact cause of most colorectal can- cers is not known, it is possible to prevent many colon cancers . Early detection can help find and remove pre-cancerous polyps (tissue growths) in the colon. It also appears that getting regular physical activity; eating plenty of fruits, vegetables, and whole-grain foods; and limiting consumption of high-fat ...

The Jonsson Cancer Center Foundation (JCCF) exists for the primary purpose of raising and distributing funds for cancer research at UCLA. Fiduciary responsibility for charitable gifts made to the JCCF rests with its 52-member board of directors, a respected group of business and community leaders who are deeply committed to the cancer center’s research mission. The JCCF offers the following diversified range of giving opportunities: ? Major and Planned Gifts ? Special Gifts ? Participation in Events ? Community Activities Major and Planned Gifts The JCCF actively welcomes significant contributions for vital research priorities identified by the cancer center leadership. Donors can choose to direct gifts to research in specific types of cancer , and appropriate naming opportunities are available. Assets that can be given include ...

This publication was prepared by: Cancer Surveillance Section Cancer Control Branch Division of Chronic Disease and Injury Control California Department of Health Services 1700 Tribute Road, Suite 100 Sacramento, CA 95815-4402 (916) 779-0300, debbie@ccr.ca.gov http://www.dhs.cahwnet.gov/ps/cdic/cdicindex.htm or http://www.ccrcal.org/ Suggested citation: Yost K, Schlag R (eds). Colorectal Cancer in California, 2001. Sacramento, CA: California Department of Health Services, Cancer Surveillance Section, February 2002. Production and design by Maggie Burgos, California Cancer Registry. Copyright information: All material in this report is in the public domain and may be reproduced or copied with- out permission; citation as to source, however, is appreciated. This and other California Cancer Registry publications are available on the World Wide Web at http:// ...

cancers cancer tumor tumors Diet and Cancer Created by: Tricia Fleming, University of Kansas Dietetic Intern Tammy Beason, MS, RD, Nutrition Education Specialist, Family Nutrition Education Program December 2001 Cancer Cancer is the 2nd most common cause of death in the US after heart disease. Cancer kills 1 out of every 4 Americans. The risk of developing cancer can be reduced by changes in a person’s lifestyle. What is Cancer ? Normal body cells grow, divide and die in an orderly fashion. Cancer cells are different because they do not die, just continue to divide and grow. Cancer cells form as a result of damaged DNA. What is Cancer ? These damaged genes can be passed on, which accounts for inherited cancers . In other ...

G EORGETOWN U NIVERSITY M EDICAL C ENTER lombardi LOMBARDI CANCER CENTER RESEARCH • EDUCATION • TREATMENT • February 2001 information packet Cancer Assessment and Risk Evaluation care Page 2 T he CARE ( Cancer Assessment and Risk Evaluation) Program is a genetic counseling and testing program offered by the Lombardi Cancer Center at Georgetown University Medical Center. A component of the CARE program is known as PATH (Personal Aid to Health). This free research study is supported by a grant from the National Institutes of Health and the National Cancer Institute. Participation in CARE/PATH Through the program, each participant meets with a genetic counselor or nurse educator to discuss: • a detailed family history and risk ...

Tumor and Normal Cell Lines from the Same Individual www.atcc.org Normal/ Tumor and Primary/Metastatic Cell Line Pairs The Global BioresourceCenter Normal Cell Line Tumor Cell Line ATCC No. Name CancerType Tissue Source CRL-7672 Hs 919.T benign osteoid osteoma bone CRL-7554 Hs 821.T giant cell sarcoma bone CRL-7552 Hs 820.T heterophilic osteofication bone CRL-7444 Hs 704.T osteosarcoma bone CRL-7448 Hs 707(A).T osteosarcoma bone CRL-7471 Hs 735.T osteosarcoma bone CRL-7595 Hs 860.T osteosarcoma bone CRL-7622 Hs 888.T osteosarcoma bone CRL-7626 Hs 889.T osteosarcoma bone CRL-7628 Hs 890.T osteosarcoma bone CRL-7453 Hs 709.T periostitis; granuloma bone CRL-5868 NCI-H1395 adenocarcinoma lung CRL-5872 NCI-H1437 ...

A Publication of the Cancer Data Registry of Idaho A Program of the Idaho Hospital Association Editors: Christopher J. Johnson, MPH, Epidemiologist Stacey L. Carson, RHIT, CTR, Vice President and Executive Director/CDRI Contributors: Denise Jozwik, RHIT, CTR, Assistant Director Jessica Shew, CTR, Cancer Data Controller December 2001 CANCER DATA REGISTRY OF IDAHO P.O. Box 1278 Boise, Idaho 83701-1278 208-338-5100 ext 213 (phone) 208-338-7800 (FAX) http://www.idcancer.org CANCER IN IDAHO - 2000 Page 2 December 2001 Cancer in Idaho - 2000 Page ii PREFACE “ Cancer in Idaho - 2000,” the twenty-fourth annual report of the Cancer Data Registry of Idaho (CDRI), contains data on cancer cases diagnosed during 2000 among Idaho residents. These data can be ...

A Publication of the Cancer Data Registry of Idaho A Program of the Idaho Hospital Association Editors: Christopher J. Johnson, MPH, Epidemiologist Stacey L. Carson, RHIT, CTR, Vice President and Executive Director/CDRI Contributors: Denise Jozwik, RHIT, CTR, Assistant Director Nancy Breier, CTR, Cancer Data Controller Jessica Shew, CTR, Cancer Data Technician December 2000 CANCER DATA REGISTRY OF IDAHO P.O. Box 1278 Boise, Idaho 83701-1278 208-338-5100 ext 213 (phone) 208-338-7800 (FAX) http://www.idcancer.org CANCER IN IDAHO - 1999 Page 2 December 2000 Cancer in Idaho - 1999 Page ii PREFACE “ Cancer in Idaho - 1999,” the twenty-third annual report of the Cancer Data Registry of Idaho (CDRI), contains data on cancer cases diagnosed during ...

Molecular Classification of Cancer : Class Discovery and Class Prediction by Gene Expression Monitoring T. R. Golub, 1,2 *† D. K. Slonim, 1 † P. Tamayo, 1 C. Huard, 1 M. Gaasenbeek, 1 J. P. Mesirov, 1 H. Coller, 1 M. L. Loh, 2 J. R. Downing, 3 M. A. Caligiuri, 4 C. D. Bloomfield, 4 E. S. Lander 1,5 * Although cancer classification has improved over the past 30 years, there has been no general approach for identifying new cancer classes (class discovery) or for assigning tumors to known classes (class prediction). Here, a generic approach to cancer classification based on gene expression monitoring by DNA microarrays is described and applied to human acute leukemias as a test case. A class ...

Special Section: Colorectal Cancer and Early Detection see page 20 WA 25,600 MT 4,400 WY 2,300 ID 5,200 OR 16,800 CO 14,500 UT 5,900 NV 9,500 CA 119,900 AZ 22,100 NM 7,100 TX 79,700 AK 1,600 ND 3,100 MN 20,800 SD 3,700 NE 7,700 KS 12,300 OK 16,900 IA 14,800 WI 25,300 MO 28,600 IL 57,400 AR 14,200 LA 21,900 TN 29,100 KY 21,100 MS 14,400 AL 22,600 GA 31,600 SC 19,500 NC 38,200 VA 31,300 FL 92,200 HI 4,700 PR N/A ME 7,000 MI 45,800 IN 30,000 OH 58,700 PA 68,900 NY 83,700 VT 2,900 NH 5,800 MA 31,700 ...

Helping Children Understand Cancer adapted from “ Cancer Care Briefs” When someone has cancer , it affects the entire family, particularly children. Cancer is a complicated disease to understand, even for adults. There are many types of cancers and no easy way to describe them in simple terms. But if you, your child, or someone in your family has cancer , discussing it with your children may be the most important thing you can do. In addition to the information provided in this publication, you can also refer to “Resources for Cancer & Parenthood” for additional resources that may be helpful. You can obtain a copy through the Cancer Resource Center at (415) 885-3693 or on the first floor 1600 Divisadero Street. Protecting Children Can Make Things Worse When cancer strikes a family, children sense that something is wrong, even if they don’t know what it is. Talking it ...

One out of every four deaths in the United States is due to cancer . 1 Nutrition is one of the important factors involved in reducing risk for cancer . 2 Soyfoods fit the dietary guidelines for reducing cancer risk, and they also contain anticarcinogens which may prove to be protective. In the United States, cancer is the second leading cause of death. 1 Lifestyle factors are important in the etiology of the disease. Cigarette smoking, physical inactivity, and poor diet all contribute to cancer risk. Scientific evidence indicates that one third of cancer deaths in the United States are due to dietary factors. 2 Epidemiological studies show that populations which consume a typical Asian diet have lower incidences of breast, prostate, and colon cancers than those consuming a Western diet. 1 The Asian diet includes mostly plant ...

Cancer Incidence In Connecticut 1999 State of Connecticut Department of Public Health Connecticut Tumor Registry 410 Capitol Avenue, MS# 13TMR P.O. Box 340308 Hartford, CT 06134-0308 November, 2001 Page 2 CANCER INCIDENCE IN CONNECTICUT, 1999 CONNECTICUT TUMOR REGISTRY OFFICE OF POLICY, PLANNING AND EVALUATION CONNECTICUT DEPARTMENT OF PUBLIC HEALTH P. O. BOX 340308 410 CAPITOL AVENUE HARTFORD CT 06134 November, 2001 This work was supported in part by Contract N01-CN-67005 between the National Cancer Institute and the Connecticut Department of Public Health. Requests for further information, and questions about this report, should be directed to the Connecticut Tumor Registry (telephone 860-509-7163). 1 Page 3 INTRODUCTION Numbers of cancers shown ...

Genetics in Primary Care: A Faculty Development Initiative Syllabus Material Colorectal Cancer Module: Page 1 Colorectal Cancer A resident asks. Why would a primary care doctor want to know about the genetics of colorectal cancer ? Key Points : • About 10% of people have a family history of colorectal cancer . These people are candidates for early initiation ofroutine colorectal cancer screening (at age 40 instead of age 50) and might be considered for more aggressive screening strategies. • The typical primary care practice, 2 to 8 patients (1/200 – 1/800) are from “high risk” families, with a condition called hereditary nonpolyposis colorectal cancer (HNPCC). These patients are have a high lifetime risk of colorectal cancer , with risk starting in their 20s, and have an increased risk for other cancers as well. • Rarely, primary ...

This issue summary should be used in conjunction with the IHS “Heritage and Health” and “IHS Profile” documents, available at http://info.ihs.gov February 2001 CANCER ISSUE Cancer is the second leading cause of death for American Indians and Alaska Natives, and rates appear to be increasing. BACKGROUND Since the Indian Health Service (IHS) has succeeded in reducing infant mortality, injuries, and infectious diseases, the population is now living long enough to experience the entire range of age-related chronic disease. Indian communities are also very concerned about the impact of environmental pollution on their health. American Indians and Alaska Natives have historically had very low rates of cancer , due in part to competing causes of death (infectious diseases like TB) but possibly also related to diet, physical activity patterns, and limited tobacco ...

Premise ISNCC Position Statement Cancer Pain November 1998 All individuals with cancer have the right to obtain optimal pain relief. Background The WHO estimates that, of the five million who die from cancer each year, four million die in uncontrolled pain. Untold suffering because of unrelieved pain continues as a major problem and presents a challenge to health care providers. The provision of pain control in care of the patients experiencing cancer merits high priority. Uncontrolled pain causes suffering and reduces quality of life. Patients often fear the symptom of pain more than they fear the cancer . Much of this suffering is, however, unnecessary since up to 90% of cancer pain can be effectively controlled. The management of cancer pain is a complex undertaking requiring assessment of the physical, social, spiritual, economic, emotional and cultural components ...

Cancer Incidence in Connecticut by Town of Residence 1997 State of Connecticut Department of Public Health Connecticut Tumor Registry 410 Capitol Avenue, MS# 13TMR P.O. Box 340308 Hartford, CT 06134-0308 April, 2000 Page 2 CANCER INCIDENCE IN CONNECTICUT BY TOWN OF RESIDENCE, 1997 CONNECTICUT TUMOR REGISTRY OFFICE OF POLICY, PLANNING AND EVALUATION CONNECTICUT DEPARTMENT OF PUBLIC HEALTH P. O. BOX 340308 410 CAPITOL AVENUE HARTFORD CT 06134 April, 2000 This work was supported in part by Contract N01-CN-67005 between the National Cancer Institute and the Connecticut Department of Public Health. Requests for further information, and questions about this report, should be directed to the Connecticut Tumor Registry (telephone 860-509- 7163) Page 3 TABLE OF CONTENTS ...

Cancer Incidence in Connecticut by Town of Residence 1998 State of Connecticut Department of Public Health Connecticut Tumor Registry 410 Capitol Avenue, MS# 13TMR P.O. Box 340308 Hartford, CT 06134-0308 September, 2001 Page 2 TABLE OF CONTENTS Introduction 3 Crude incidence rates for all invasive cancers , by town Males 5 Females 13 Numbers of cancers for selected common sites (types), by town, Excluding lymphomas Males 21 Females 35 Non-Hodgkin's lymphoma, by town, males and females 50 2 Page 3 INTRODUCTION This report is an update of “ Cancer Incidence in Connecticut by Town of Residence, 1997.” This report provides data for can- cers diagnosed in 1998. As in the previous report, the numbers of cancers shown in this report are invasive ...

Cancer Pain Treatment Guidelines for Patients National Comprehensive Cancer Network NCCN ® Version I January 2001 Page 2 Page 3 The mutual goal of the National Comprehensive Cancer Network ® (NCCN ® ) and the American Cancer Society (ACS) partnership is to provide patients and the general public with state-of-the-art cancer treatment information in under- standable language. This information, based on the NCCN’s Clinical Practice Guidelines, is intended to assist you in the dialogue with your physician. These guidelines do not replace the expertise and clinical judgment of your physician. Each patient’s situation must be evaluated individually. It is important to discuss the guidelines and all information regarding treatment options with your physician. ...

cancers cancer tumor tumors TITLE: Orbital Tumors SOURCE: Grand Rounds Presentation, UTMB, Dept. of Otolaryngology DATE: October 31, 2001 RESIDENT PHYSICIAN:Michael Underbrink, MD FACULTY PHYSICIAN: Shawn Newlands, MD SERIES EDITORS: Francis B. Quinn, Jr., MD and Matthew W. Ryan, MD [ Grand Rounds Index | UTMB Otolaryngology Home Page ] "This material was prepared by resident physicians in partial fulfillment of educational requirements established for the Postgraduate Training Program of the UTMB Department of Otolaryngology/Head and Neck Surgery and was not intended for clinical use in its present form. It was prepared for the purpose of stimulating group discussion in a conference setting. No warranties, either express or implied, are made with respect to its accuracy, completeness, or timeliness. The material does not necessarily reflect the ...

Cancer Incidence in Connecticut 1980-1996 State of Connecticut Department of Public Health Connecticut Tumor Registry 410 Capitol Avenue, MS# 13TMR P.O. Box 340308 Hartford, CT 06134-0308 October, 1999 Page 2 CANCER INCIDENCE IN CONNECTICUT, 1980-1996 Connecticut Department of Public Health, 410 Capitol Avenue, Hartford CT 06134-0308. Supported by Contract N01-CN-67005 between the National Cancer Institute and the Connecticut Department of Public Health. Anthony P. Polednak, Ph.D. Epidemiologist Connecticut Tumor Registry Connecticut Department of Public Health, 1999 (860) 509-7163 Page 3 TABLE OF CONTENTS Introduction 1 References 3 Age-standardized rates 5 Age-specific rates All sites combined 7 Uterine Corpus ...