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Cancer Incidence in Connecticut 1980-1998 State of Connecticut Department of Public Health Connecticut Tumor Registry 410 Capitol Avenue, MS# 13TMR P.O. Box 340308 Hartford, CT 06134-0308 April, 2001 Page 2 CANCER INCIDENCE IN CONNECTICUT, 1980-1998 Connecticut Department of Public Health, 410 Capitol Avenue, Hartford CT 06134-0308. Supported by Contract N01-CN-67005 between the National Cancer Institute and the Connecticut Department of Public Health. Anthony P. Polednak, Ph.D. Epidemiologist Connecticut Tumor Registry Connecticut Department of Public Health (860) 509-7163 Page 3 TABLE OF CONTENTS Introduction 1 References 3 Age-standardized rates 6 Age-specific rates All sites combined 8 Uterine Corpus 23 ...

Cancer Incidence in Connecticut Counties, 1997 State of Connecticut Department of Public Health Connecticut Tumor Registry 410 Capitol Avenue, MS# 13TMR P.O. Box 340308 Hartford, CT 06134-0308 March, 2001 Page 2 CANCER INCIDENCE IN CONNECTICUT COUNTIES, 1997 CONNECTICUT TUMOR REGISTRY OFFICE OF POLICY, PLANNING AND EVALUATION CONNECTICUT DEPARTMENT OF PUBLIC HEALTH P.O. BOX 340308 410 CAPITOL AVENUE HARTFORD CT 06134 MARCH 2001 This work was supported in part by Contract N01-CN-67005 between the National Cancer Institute and the Connecticut Department of Public Health. Requests for further information, and questions about this report, should be directed to P. D. Sullivan at the Connecticut Tumor Registry (telephone 860-509-7167) Page 3 TABLE OF CONTENTS Executive ...

THE CONNECTICUT TUMOR REGISTRY __ State of Connecticut Department of Public Health Connecticut Tumor Registry 410 Capitol Avenue, MS# 13TMR P.O. Box 340308 Hartford, CT 06134-0308 July, 2001 Page 2 1 INTRODUCTION The Connecticut Tumor Registry, located in the Department of Public Health, is a population-based resource for examining cancer patterns in Connecticut. The Registry has been part of the National Cancer Institute's Surveillance, Epidemiology and End Results (SEER) Program since 1973. About 90% of the Registry's funding comes from the SEER Program. The SEER Program is a unique and important resource. The SEER Program has included registries covering Atlanta, Connecticut, Detroit, Hawaii, Iowa, the Los Angeles area, the San Francisco area, San Jose-Monterey CA, New Mexico, ...

640 CANCER BIOLOGY PROGRAM Chair and Program Director: J. Martin Brown Committee on Cancer Biology: J. Martin Brown (Professor of Radiation Oncology), Glenn Rosen (Assistant Professor of Medicine), Jeffrey Axelrod (Assistant Professor of Pathology), Stanley Cohen (Profes- sor of Genetics), Branimir Sikic (Professor of Medicine), Michael Simon (Associate Professor of Biological Sciences) The Cancer Biology Program is designed to provide a framework for students with an interest in the understanding and control of neoplastic growth and to build a curriculum in varied biomedical areas relevant to that subject. Students in this program are based in departments appropri- ate to their specialty and are subject to the core requirements specified below. A Ph.D. is offered in Cancer Biology. GRADUATE PROGRAM DOCTOR OF PHILOSOPHY University requirements for the Ph.D. ...

Canadian Strategy for Cancer Control Executive Summary “Improved management of the system will require enhanced partnerships among policy makers, service providers and users of the system through more collaborative planning, priority setting, public policy development and implementation.” First Ministers’ Vision (2000) • Cancer is the disease Canadians most fear. One in three Canadians will develop cancer during their lifetime and one half of these will become long-term survivors. Most Canadians know at least one person affected by cancer . • Gaps between supply of services and demand on the cancer care system, particularly of human resources, are already evident in lengthy waiting lists and patients being sent elsewhere for care. • The number of cancer cases in Canada will more than double over the next fifteen years ...

Washington State Cancer Registry Page 15 Cancer By Site Page 2 Percent Distribution of Cancer 1999 Total Cancer Incidence of Washington State Residents 2.2% 1.9% 1.9% 1.5% 1.5% 1.3% 1.1% 0.9% 0.8% 0.8% 0.7% 0.6% 0.6% 18.5% 14.9% 12.7% 10.0% 7.0% 6.3% 4.2% 3.8% 2.7% 2.2% 2.0% 0.1% 0 1000 2000 3000 4000 5000 6000 Breast (Female) Prostate Lung and Bronchus Colorectal Other Melanoma of the Skin Bladder Non-Hodgkins Lymphoma Endometrium Leukemia Kidney and Renal Pelvis Oral Cavity and Pharynx Pancreas Ovary Thyroid Brain Stomach Esophagus Multiple Myeloma Larynx Cervix (Uterine) Liver Testis Hodgkins Lymphoma ...

25 IAEA BULLETIN, 43/2/2001 IMPROVING CANCER CARE INCREASED NEED FOR RADIOTHERAPY IN DEVELOPING COUNTRIES BY VIC LEVIN,AHMED MEGHZIFENE, JOANNA IZEWSKA AND HIDEO TATSUZAKI C ancer is not a modern phenomenon – a bone tumour has been observed in a 14-year-old pharaoh who succumbed and was mummified, only to be accurately diagnosed three millennia later. Chinese and Arabic medical writings also document clinical cases so well that some can clearly be identified today as cancer from the descriptions. Cancer is a rapidly increasing problem in developing countries as statistics illustrate. Cases have risen from two million in 1985 to five million in 2000, and are projected to number 10 million in 2015. In developed countries, where there were five million cases in 1985 as well as in 2000, no ...

E d i t o r i a l Singapore Med J 2001 Vol 42(7) : 290 Vulvar Cancer – (r)evolution in Management A Ilancheran National University Hospital 5 Lower Kent Ridge Road Singapore 119074 A Ilancheran, MBBS, MMed, FRCOG, MD, FAMS Associate Professor & Senior Consultant Tel: (65) 772 4261 Fax: (65) 779 4753 Email: obgia@nus.edu.sg Vulvar cancer is rare in Singapore. This issue has the first reported series of vulvar cancer in Singapore. It is timely to remind ourselves of the (r)evolution that has occurred in the treatment of this disease (1) . There is no other gynaecological cancer that has undergone so much change in management as vulvar cancer . The change mirrors what happened in the surgical management of breast cancer . Following the Halsteadian principle and the pioneering ...

JAMA PATIENT PAGE Protect against cervical cancer The JAMA Patient Page is a public service of JAMA and the AMA. The information and recommendations appearing on this page are appropriate in most instances, but they are not a substitute for medical diagnosis. For specific information concerning your personal medical condition, JAMA and the AMA suggest that you consult your physician. This page may be reproduced noncommercially by physicians and other health care professionals to share with patients. Any other reproduction is subject to AMA approval. To purchase bulk reprints, call 212/354-0050. ervical cancer was previously one of the most common causes of death due to cancer among American women. Early detection and treatment of conditions that could lead to cervical cancer have resulted in a major decline in the number of deaths in recent years. Yet the American Cancer ...

JAMA PATIENT PAGE Detecting skin cancer The JAMA Patient Page is a public service of JAMA and the AMA. The information and recommendations appearing on this page are appropriate in most instances; but they are not a substitute for medical diagnosis. For specific information concerning your personal medical condition, JAMA and AMA suggest that you consult your physician. This page may be reproduced noncommercially by physicians and other health care professionals to share with patients. Any other reproduction is subject to AMA approval. Bulk reprints available by calling 212/354-0050. ears of worshipping the sun or overexposure to the sun’s ultraviolet (UV) rays may have made you vulnerable to developing skin cancer . Dermatologists recommend that you do periodic self-examinations for any changes in the number, size, shape, and color of pigmented areas of your skin, such as freckles ...

513 RADIATION RESEARCH 151 , 513–531 (1999) 0033-7587/99 $5.00 1999 by Radiation Research Society. All rights of reproduction in any form reserved. REVIEW Cell Phones and Cancer : What Is the Evidence for a Connection? 1 J. E. Moulder, a L. S. Erdreich, b R. S. Malyapa, c J. Merritt, d W. F. Pickard e and Vijayalaxmi f a Radiation Oncology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, Wisconsin 53226; b Bailey Research Associates, 292 Madison Avenue, New York, New York 10017; c Radiation Oncology, Washington University, 4511 Forest Park Boulevard, St. Louis, Missouri 63108; d Radio-Frequency Radiation Branch, Air Force Research Laboratory, Brooks Air Force Base, Texas 78235; ...

R C Rene Caissse?s Story Continues In China ?I Was Canada?s Cancer Nurse.? R Page 2 INTRODUCTION by Maurine B. Cox A most amazing story comes from a small town in Canada, about a nurse who discovered a beneficial treatment for cancer , which she named ESSIAC (Caisse spelled backwards). Miss Caisse states that she was naive enough to think she could accumulate enough proof so that her treatment would be acceptable to the Medical profession, believing, of course, that the Cancer organizations were really looking for a cure for this dreaded disease. But the more proof she succeeded in producing, the more determined they were that it should not be made available to suffering humanity, so she went on helping and healing for years, without aid. They could not discredit her work, and she ran an open cancer clinic ...

Southwest Oncology Group Clinical Research Associate Manual CHAPTER 4 CANCER CONTROL Page 2 Southwest Oncology Group Clinical Research Associate Manual 4-2 CANCER CONTROL J UNE 2000 Introduction The cancer control research committee of the Southwest Oncology Group was formed in 1986. Since then it has grown steadily, and has generated much enthusiasm among Southwest Oncology Group investigators. NCI defines cancer control as "the reduction of cancer incidence, morbidity and mortality through an orderly sequence from research on interventions and their impact in defined populations to the broad, systematic application of the research results." The essence of this definition is the word intervention . Cancer control focuses on specific, well-defined actions to reduce cancer incidence, morbidity and ...

14 Lawrence Livermore National Laboratory revolutionary new tool for analyzing and planning radiation treatment for cancer patients will be appearing in hospitals within the next few years. Using their storehouse of knowledge and data on nuclear science and radiation transport, Lawrence Livermore scientists have developed PEREGRINE, a hardware and software system that addresses the problem of radiation therapy dosage using fundamental physics principles. Each year, about 100,000 Americans die from cancerous tumors that doctors thought were curable. Using current methods for analyzing radiation, doctors unknowingly leave areas of the tumors untreated. Livermore researchers hope that PEREGRINE will improve the efficacy of radiation therapy by helping doctors to direct the radiation accurately. According to Ralph Patterson, who is leading the project, “The PEREGRINE dose calculation ...

OFFICE OF PUBLIC HEALTH AND SCIENCE U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Closing the Gap Closing the Gap A newsletter of the Office of Minority Health, U.S. Department of Health and Human Services August 2000 Lifting the Unequal Burden of Cancer on Minorities and the Underserved NCI Develops Strategic Plan to Reduce Cancer -Related Health Disparities continued on page 2 The Office of Minority Health has a new Web Site! Visit us at: http:// www.omhrc.gov. By Houkje Ross Harold P.Freeman, MD, named NCI Associate Director for Reducing Health Disparities. FPO T he National Cancer Institute (NCI) recently un- veiled a major new effort to identify and address the underlying causes of cancer -related disease and disability in racial and ethnic ...

Reduce your cancer risk by • Eating a variety of foods in moderation, and • Using physical activity to help achieve and maintain a healthy weight. Food choices are one of the cancer risk factors you can control. Protective Factors What you eat can make a difference in your health — and in your risk for cancer . The following recommendations are also part of the Dietary Guidelines from the U.S. Department of Agriculture. Risk Factors Other foods — when eaten in excess — can have a negative effect on your health and increase your cancer risk. 1. High-fat foods A diet containing many high-fat foods can increase your risk for breast, colon, and prostate cancer . High fat also means high calorie and that can lead to being over- weight. Choose lean meat, fish, skinned poultry, and low-fat dairy products most often and limit ...

Control of pain in patients with cancer S I G N PSYCHOSOCIAL ISSUES B A thorough assessment of the patient’s psychological and social state should be carried out. This should include assessment of anxiety and, in particular, depression, as well as the patient’s beliefs about pain. Quick Reference Guide EDUCATION B Pre-registration curricula for health care professionals should place greater emphasis on pain management education. B Continuing pain management education programmes should be available to all health care professionals caring for patients with cancer . ASSESSMENT B Prior to treatment an accurate assessment should be performed to determine the type and severity of pain, and its effect on the patient. B The patient should be the prime assessor of his or her pain. C For effective ...

79 Chapter Four TUMOR REGISTRIES A tumor registry is a cancer data system that provides continued follow-up care on all cancer patients in a given location, hospital, or state. A tumor registry documents and stores all significant elements of a patient’s history and treat- ment. Many registry databases include information concerning demographics, medical history, diagnostic findings, primary site, histological type of cancer , stage of disease, treatment(s), recurrence, subsequent treatment, and end results. A variety of studies and reports can be generated from the information contained in tumor registries. Several registries also collect patient specimens, such as blood samples or slides of resected tumors . These specimens may be used for educational purposes as case studies or for research purposes. Several tumor registries that collect tissue specimens ...

Onconurse.com Fact Sheet 1 Siblings of Children with Cancer be old enough to understand that death is a possibility. There are plenty of reasons for concern. Fear It is very common for young siblings of children with cancer to think that the disease is contagious, that they can “catch it.” Many also worry that one or both parents may get cancer . The diagnosis of cancer changes chil- dren’s views that the world is a safe place. They feel vulnerable, and they are afraid. Depending on their age, siblings worry that their brother or sister may get sicker or may die. Some siblings develop symptoms of illness in an attempt to regain attention from the parents. Fears of things other than cancer may emerge: fear of being hit by a car, fear of dogs, fear of strangers. Many fears can be quieted by accurate and age-appropriate explanations from the parents ...

COLORECTAL CANCER SCREENING Colorectal cancer is the second leading cause of cancer related deaths in the United States. There is a 1 in 16 lifetime chance of developing colorectal cancer . The disease strikes men and women in equal proportions. For those persons with a family history of colorectal cancer , the risk may increase significantly. Colorectal cancer has a high survival rate if detected early. Screening Recommendations 1. All persons aged 50 or older should be screened for colorectal cancer with yearly fecal occult blood testing (FOBT), a flexible sigmoidoscopy every five years, or both. The American Cancer Society recommends flexible sigmoidoscopy and FOBT while the U.S. Preventive Services Task Force recommends either or both tests for colorectal cancer screening. 2. FOBT should be performed on three consecutive stool specimens. To correctly perform FOBT, ...

A Patient’s Guide to Colorectal Cancer Screening Screening is a medical intervention, and, as such, has costs, risks, benefits, and disadvantages. Because of this, it is imperative that you, the patient, be informed of the potential benefits and disadvantages of screening procedures. This material is intended to provide you with background information about Colorectal Cancer Screening. If you have questions, please do not hesitate to discuss them with your health care provider. Colorectal Cancer is the second most common form of cancer in the U.S. among men and women, and ranks second in the death rate. Unless you are a patient with high risk for colorectal cancer , colorectal cancer takes a long time to develop and grows slowly. It is believed that colorectal cancers develop from benign polyps in the colon. It can take 5 years for adenomatous (benign) polyps to form from the normal lining of the colon and ...

the spectrum of health care, including cancer centers, intensive care units, and nursing homes, cancer pain continues to be both prevalent and undertreated. Pain can be associated with both localized tumors and metastatic cancer . Although Daut and Cleeland 1 reported only 15% of patients with nonmetastatic dis- ease had pain associated with their tumor at the time of diagnosis,pain becomes more pervasive as disease pro- gresses. With the diagnosis of metastatic disease at the University of Wisconsin,the percentage of patients hav- ing pain increased to 74%. Direct tumor involvement is the most common cause of pain, present in approxi- mately two thirds of patients with pain from metastatic cancer . 2 Tumor invasion of bone,common in breast and prostate cancer and with multiple myeloma, accounts Cancer Pain Management ...

SEER Program 47 National Cancer Institute RACIAL/ETHNIC PATTERNS however, lacking in the U.S. mortality data and intercensual population estimates. With the exception of Chinese, Japanese, and Filipinos, detailed information for other Asian populations is not available from U.S. mortality data. Hispanic ethnicity has been available in U.S. mortality data for all 50 states only since 1990. Denominator counts for detailed racial/ethnic groups are available only at the 1990 census, making it possible to compute incidence and mortality rates for short time periods around the census, but not long-term trends. Changes in the definition of Hispanic status over time, both by SEER and by the Bureau of the Census, also complicate the computation of rates and trends. Finally, the lack of life-table data for several specific groups, for example Koreans and ...

ICCC VI 79 RENAL TUMORS 79 National Cancer Institute 79 National Cancer Institute SEER Pediatric Monograph 79 National Cancer Institute SEER Pediatric Monograph Leslie Bernstein, Martha Linet, Malcolm A. Smith, Andrew F. Olshan HIGHLIGHTS Incidence ? Malignancies of the kidney (renal cancers ) represented 6.3% of cancer diagnoses among children younger than 15 years of age (incidence 7.9 per million) (Table VI.2) and 4.4% of cancer diagnoses for children and adolescents younger than 20 years of age (incidence of 6.2 per million). ? In the US approximately 550 children and adolescents younger than 20 years of age are diagnosed with renal tumors each year, of which approximately 500 are Wilms’ tumor . ? Wilms’ tumor was by far the most common form of renal cancer ...

ICCC VIII MALIGNANT BONE TUMORS 99 National Cancer Institute SEER Pediatric Monograph HIGHLIGHTS Incidence ? Malignancies of the bone, with an average annual incidence rate of 8.7 per million children younger than 20 years of age, comprised about 6% of childhood cancer reported by SEER areas from 1975-95. ? In the US, 650-700 children and adolescents younger than 20 years of age are diagnosed with bone tumors each year of which approximately 400 are osteosar- coma and 200 are Ewing’s sarcoma. ? The two types of malignant bone cancer that predominated in children were os- teosarcomas and Ewing’s sarcomas, about 56% and 34% of the malignant bone tumors , respectively. ? Osteosarcomas derive from primitive bone-forming mesenchymal stem cells and most often occur near the metaphyseal portions of the long bones. ...

XII 149 National Cancer Institute SEER Pediatric Monograph CANCER AMONG INFANTS HIGHLIGHTS Incidence ? The age of peak cancer incidence among children occurred during the first year of life (Figure XII.1). ? Malignancies of infancy represented 10% of all cancer that was diagnosed among children younger than 15 years of age. The average annual incidence rate of all infant cancer combined was 233 per million infants, which was 12% higher than the age (2 years) with the next highest incidence. ? The rate among females (234 per million infants) was essentially the same as that in males (232 per million infants). This is notable because infancy was the only age among children younger than 15 years of age in which female rates were not lower than male rates. ? Neuroblastoma comprised 28% of infant cancer cases and ...

ICCC VII HEPATIC TUMORS Marc Bulterys, Marc T. Goodman, Malcolm A. Smith, Jonathan D. Buckley 91 National Cancer Institute SEER Pediatric Monograph HIGHLIGHTS Incidence ? Primary neoplasms of the liver are rare in children, comprising only 1.1% of malig- nancies for children younger than 20 years of age. In the US, 100-150 children are diagnosed with liver cancer each year. ? Primary liver cancer is subdivided into the following histologic subtypes: hepatoblastoma comprises over two-thirds of the malignant tumors of the liver in children and adolescents (79% <15 years of age; 66% <20 years of age) and hepatocellular carcinoma accounts for most of the remaining cases. Hepatoblastoma occurs primarily in children younger than 5 years of age while hepatocellular carcinoma occurs primarily after 10 years of age (Figure VII.2). ...

XV 171 National Cancer Institute SEER Pediatric Monograph OTHER RESOURCES AVAILABLE AT NCI/NIH Cancer Information Service (CIS) – 1-800-4- CANCER or http://cis.nci.nih.gov/contact/faqform.html ? The Cancer Information Service is the National Cancer Institute’s link to the public, providing current scientific information in understandable language to patients, their families, the general public and health professionals. Through a network of 19 regional offices located throughout the country, the CIS serves the entire United States and Puerto Rico. CIS staff are available Monday through Friday from 9:00 a.m. to 4:30 p.m. local time. Callers with TTY equipment may call 1–800–332–8615. Recorded informa- tion on cancer topics is available 24 hours a day. NCI publications on childhood cancer : Available by calling 1-800-4- CANCER (1-800- ...

XIII 157 National Cancer Institute SEER Pediatric Monograph CANCER AMONG ADOLESCENTS 15-19 YEARS OLD HIGHLIGHTS Incidence ? The incidence of cancer among adolescents (i.e., 15-19 year-olds) in SEER areas for 1986-95 was 202.2 per million, which was similar to the incidence of cancer among 0-4 year-olds and substantially greater than the incidence for 5-9 and 10-14 year- olds (Table XIII.1). ? The spectrum of cancers that occurred among 15-19 year-olds was distinctive from those that occurred in young children. For SEER areas from 1986-95, the most common tumors among adolescents were Hodgkin’s disease (16.1%), germ cell tumors (15.2%), CNS tumors (10.0%), non-Hodgkin’s lymphoma (NHL) (7.6%), thyroid cancer (7.2%), malignant melanoma (7.0%), and acute lymphoblastic leuke- mia (ALL) (6.4%) (Figure XIII.1 and Table XIII.1). ...

Bioluminescent Bioreporter Integrated Circuits (BBICs) for Tumor -Specific Protein Detection Gary S. Sayler, Steven Ripp, Bruce M. Applegate, David E. Nivens, Gerald E. Jellison Jr., and Michael L. Simpson Center for Environmental Biotechnology, University of Tennessee, Knoxville, Tennessee 37996 and Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831 A promising approach for advanced identification of cancerous or precancerous cells is the detection of tumor -specific secreted proteins in body fluids. This represents a unique approach as it allows for the detection of cancer cells based on signature protein secretions rather than on the identification of a distinguishable tumor mass or other major physiological change. We believe that a sentry of reporter cells can be developed that will emit bioluminescent signals in response to signature tumor protein molecules. Thus, cancer cells can ...