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A new drug reduced almost by half the risk that post- menopausal survivors of early- stage breast cancer would suf- fer a relapse, according to an internation- al study released in October. The drug, letrozole (sold as Femara), brings new hope for a disease-free future for hun- dreds of thousands of breast cancer sur- vivors. The international study of more than 5,000 postmenopausal women found that letrozole, when taken shortly after com- pleting five years of tamoxifen therapy, cut estrogen-sensitive breast cancer recurrences by almost half. These results were so persuasive that the study was halted early to get the news to the public and allow women to begin the therapy. Lombardi Comprehensive Cancer Center is one of the sites that enrolled patients on this study. Claudine Isaacs, MD, associate professor and clinical director ...

MISSION The mission of Y-ME National Breast Cancer Organization is to ensure, through information, empowerment and peer support, that no one faces breast cancer alone. NATIONAL PROGRAMS & SERVICES 24-hour Y-ME National Breast Cancer Hotline 1-800-221-2141 (English)* • 1-800-986-9505 (Spanish) The only hotline in the United States staffed by trained peer counselors who are breast cancer survivors. It is a convenient, confidential resource for breast cancer and breast health information, as well as support for anyone touched by or concerned about this disease. Callers can be matched with a survivor, patient and/or supporter who have had a similar experience with breast cancer . * Interpreters available in 150 languages. ShareRing Network A monthly, one-hour teleconference featuring a breast cancer related presentation ...

Y-ME National Breast Cancer Organization TM guide Understanding Your Breast Cancer Pathology Report A Guide for Breast Cancer Patients Page 2 pathology repor our t Being diagnosed with breast cancer is a life-changing event. There are many different emotional reactions to deal with and an enormous amount of information to learn. A call to the Y-ME National Breast Cancer Hotline can help with both. Newly diagnosed women and men, their families and friends, need information that will educate them about breast cancer , possible treatments and prognosis. The pathology report can be a major source of this information. Unfortunately, the pathology report is sometimes written in terms that frequently only pathologists and other medical ...

A Woman’s Guide to Breast Care Y-ME National Breast Cancer Organization TM Page 2 Breast self-examination (BSE) takes just a few minutes, and you only do it once a month. As you do your examination, keep in mind that your goal is to become acquainted with how your breasts normally LOOK and FEEL. You will become more familiar with your breasts if you perform BSE on a regular basis. This knowledge may help you identify a change, which should be reported to your medical professional. What changes should I look for? • Lump or thickening in or near the breast or underarm area • Change in the size and/or shape of the breast • Puckering, dimpling and/or redness of the breast skin • Scaliness, redness, itching and/or swelling of the nipple or surrounding area When should I perform BSE? ...

RISK FACTOR INFORMATION FOR SELECTED CANCER TYPES Source: Community Assessment Program, Bureau of Environmental Health Assessment, Massachusetts Department of Public Health December, 2002 Breast Cancer Breast cancer is the most frequently diagnosed cancer among women in both the United States and in Massachusetts. According to the North American Association of Central Cancer Registries, female breast cancer incidence in Massachusetts is the fifth highest among all states (Chen et al, 2000). Although during the 1980s breast cancer in the U.S. increased by about 4% per year, the incidence has leveled off to about 110.6 cases per 100,000 (ACS 2000). A similar trend occurred in Massachusetts and there was even a slight decrease in incidence (1%) between 1993 and 1997 (MCR 2000). In the year 2002, approximately 203,500 women in the U.S. will be diagnosed ...

RISK FACTOR INFORMATION FOR SELECTED CANCER TYPES Breast Cancer Breast cancer is the most frequently diagnosed cancer among women in both the United States and in Massachusetts. According to the North American Association of Central Cancer Registries, female breast cancer incidence in Massachusetts is the fifth highest among all states (Chen et al, 2000). Although during the 1980s breast cancer in the U.S. increased by about 4% per year, the incidence has leveled off to about 110.6 cases per 100,000 (ACS 2000). A similar trend occurred in Massachusetts and there was even a slight decrease in incidence (1%) between 1993 and 1997 (MCR 2000). In the year 2003, approximately 211,300 women in the U.S. will be diagnosed with breast cancer (ACS 2003). Worldwide, female breast cancer incidence has increased, mainly among women in older age groups whose ...

Diana Moran. Patron of the Breast Cancer Campaign, visited the University recently to see the work of Dr Philippa Darbre in the School of Animal and Microbial Sciences October 2002 The Breast Cancer Campaign has awarded Dr Phillipa Darbre from the School of Animal and Microbial Sciences £78,500 over three years to research into why some patients develop a resistance to hormone therapy and when this is likely to happen. Treatments could then be alternated, which will provide much more effective treatment and prolong life expectancy. Dr Darbre said, “Hormone therapy works for people for varying lengths of time but eventually it fails. At the Pioneering breast cancer research Did you know that there are at least 165 species of spider within a 1km radius of the University ...

How you can help people with breast cancer VOLUNTEERING FOR BREAST CANCER CARE Page 2 Volunteers play a central and important role in helping us deliver our services at national, regional and local levels. They are vital to the organisation and highly valued by Breast Cancer Care staff and clients. Page 3 What can volunteers do? Health promotion and outreach volunteers raise awareness about Breast Cancer Care and breast awareness in their local community by giving out information and attending events on our behalf. Volunteer peer supporters offer one-to-one support to people with breast cancer and their partners, usually by telephone (for this you must have personal experience of breast cancer ...

Prof. Chris Robertson Age at any birth and Breast Cancer Risk This project will review previously published models of the effect of parity and age at any birth on breast cancer risk. These models are conceptually similar and one aim is to write a general model such that various restrictions on the parameters of the general model yield the specific models. A second aim is to apply these models to a large series of Case Control studies. I expect that there will be developments in the areas of using spline functions and other flexible curves to improve the validity of the models. Background. Parity and age at first birth have long been identified as risk factors for breast cancer . Relative to nulliparous women, parous women have a decreased risk of breast cancer . The risk of developing breast cancer is greater among women with a later age at first birth compared ...

Continuing to Reduce the Excess Burden of Breast Cancer Incidence and Mortality among California Women Ngina Lythcott, Dr.P.H. Page 2 1 Introduction This paper is written from the perspective of a breast cancer survivor-advocate. While the writer is trained as a public health professional and is a fifteen-year survivor of breast cancer , she writes this paper from her experience working with and supporting many hundreds of women who have had an initial diagnosis of breast cancer or a reoccurrence of the disease. It is this experience that motivates the writer’s interest in and influences much of her thinking about the important role of breast cancer research in the reduction of excess burden and the eradication of the disease. 12 The focus of this paper is the reduction of excess ...

Breast Cancer in the Family - What does this mean for you? Information for women with a low or moderate lifetime risk of breast cancer Last updated Mar 2002 Seen in clinic by. CLIN ICAL GENETICS CLINICAL G ENE TICS For more information: If you need more advice about any aspect of inherited cancer , you are welcome to contact: Clinical Genetics Department 7th Floor, New Guy's House Guy's Hospital, St. Thomas Street London SE1 9RT Telephone: 020 7955 4648 Facsimile: 020 7955 2550 Page 2 We hear a lot about "inherited breast cancer ". This can be confusing and alarming. As breast cancer is fairly common, many women have at least one relative with this type of cancer . Yet most of those women do not have an "inherited" type of breast ...

115 Proclamations Proc. 7711 Americans to celebrate this week with appropriate programs, ceremonies, and activities to recognize the many contributions of our Nation’s minority enterprises. IN WITNESS WHEREOF, I have hereunto set my hand this twenty-six day of September, in the year of our Lord two thousand three, and of the Inde- pendence of the United States of America the two hundred and twenty- eighth. GEORGE W. BUSH Proclamation 7711 of October 3, 2003 National Breast Cancer Awareness Month, 2003 By the President of the United States of America A Proclamation Breast cancer touches the lives of many Americans, either directly or through the diagnosis of a family member or friend. We have made consid- erable progress in diagnosing this disease and improving treatments, but we have not ended it. While overall death rates are declining, ...

breast cancer 1 THE REGISTRATION OF BREAST CANCER The anatomy of the breast , the pathology and treatment of breast cancer , and collecting breast cancer data 2 FIVE FACTS ABOUT BREAST CANCER Incidence: 1 in 9 women in the TCR area develop breast cancer during their lifetime. 0.5% of breast cancer cases occur in men. Survival: Now improving. Depends on stage at diagnosis. 90% at 5yrs for localised disease, 77% at 5 yrs if lymph nodes involved. Most common agegroup: 50 - 70 yrs Population most at risk: A disease of the western ...

i Susceptibility genes in hereditary breast cancer Department of Obstetrics and Gynecology, Helsinki University Central Hospital Pia Vahteristo, email: pia.vahteristo@helsinki.fi Breast cancer is the most common malignancy among women worldwide. Most cases are sporadic, but an estimated 5-10% are due to hereditary predisposition. Two major susceptibility genes, BRCA1 and BRCA2 , have thus far been identified. Germline mutations in BRCA1 and BRCA2 explain the majority of families with both early-onset breast cancer and ovarian cancer , but a considerably lower fraction of families with site-specific breast cancer . This suggests the presence of other predisposing genes. The contribution of BRCA1 and BRCA2 to breast cancer incidence remains also unresolved, presumably because most studies have focused on high-risk families with multiple affected relatives, on ...

K ENTUCKY B REAST C ANCER T ASK F ORCE R EPORT C ARD O CTOBER 2003 This report card was prepared by Gilbert H. Friedell, M.D., Linda Linville, Ph.D., Connie Sorrell, M.P.H., Bin Huang, M.S., and Joe Petrik, M.A., M.Sc. Dr. Friedell is Director Emeritus of the Markey Cancer Center, University of Kentucky and Executive Director of the Kentucky Breast Cancer Task Force. Dr. Linville is Director, Cancer Control Practice, Markey Cancer Control Program, University of Kentucky and Co-Director of the Kentucky Breast Cancer Task Force. Ms. Sorrell is Director, Kentucky Cancer Program, Brown Cancer Center, University of Louisville and Co-Director of the Kentucky Breast Cancer ...

FOR IMMEDIATE RELEASE 08/19/03 For more information: shughes@wellnesscommunitytn.org Newly Diagnosed with Breast Cancer ? There is Help. A New Support Group brought to you by The Wellness Community Knoxville, TN (August 19, 2003) – The Wellness Community, a national non-profit organization based in Knoxville, will be starting a specialized support and education group targeting females who are Newly Diagnosed with Breast Cancer . This unique 10-week program, starting September 18 th at 10am, will feature information on education and support designed to help patients navigate through the maze of decisions and emotions accompanying the diagnosis of breast cancer . Each 2-hour meeting allows an hour for an educational program and another hour for questions, answers, and sharing among participants. Betsy Boyd, breast cancer ...

Breast Cancer Bulletin October 2003 October 2003 marks the 10th anniversary of Breast Cancer Awareness Month – one of the key health awareness campaigns in the UK. Breast cancer is the most common form of cancer in the UK and this country has one of the highest rates in Europe. We have seen a worrying rise in UK incidences of breast cancer — according to the latest statistics available, over 40,000 women and around 300 men are now being diagnosed with the disease every year ( Breast Cancer Forum statistics, July 2003). The good news is more women are surviving than ever before. According to the latest statistics, the five year survival rate for women diagnosed with breast cancer is now 74% ( Breast Cancer Forum statistics, July 2003). However, we cannot afford to become complacent on the issue as an average of 1,000 ...

Breast Cancer Bulletin February 2004 Members of the Group held health minister Melanie Johnson accountable on areas ranging from the importance of research into how to prevent breast cancer , to the patenting of the two known genes (BRCA1 and BRCA2) involved in familial breast cancer , to the series of targets for breast cancer set out in the NHS Cancer Plan. Screening Members paid particular attention to the low uptake in some areas of invitations for routine appointments with the NHS Breast Screening Programme. Long delays in diagnosis also caused concern. Whilst acknowledging the overall success of the screening programme, which celebrated its 15th anniversary in 2003, former Joint Chair Alice Mahon MP raised concerns over the low uptake of invitations to screening appointments in some areas of the country, in particular across ...

3/22/2004 Association of antibiotic use with breast cancer Word Count – 248 To the Editor: In a recent article in JAMA, Velicer et al (1) performed a case-control study involving patients enrolled in an HMO and concluded, “use of antibiotics is associated with increased risk of incident and fatal breast cancer .” This would seem to demand a change in medical practice; however, it belies potent design flaws of the study. First, the analysis lacks a test of specificity; that is, to both show the presence of an association where postulated as well as a lack of association where not expected (e.g., that prescriptions of antihypertensives, antidepressants, or other common medications are uncorrelated with breast cancer risk). A classic example of such a problem is the report linking reserpine to breast cancer some 30 years ago that was later refuted (2). Second, although the ...

About Rethink Breast Cancer Rethink Breast Cancer is fighting breast cancer and expanding support for the cause through innovative research and awareness. We are a national volunteer-driven charity with a bold, enterprising and entrepreneurial approach. Rethink uses creative and unconventional ways to communicate about breast cancer in order to transform attitudes, debunk myths and reach women and men who feel unaffected by the breast cancer cause. Rethink is tapping into the art, entertainment and fashion communities to re-energize the breast cancer movement and tackle the serious issues of breast cancer in a creative and strongly positive way. Our Audience Rethink Breast Cancer ’s target audience is modern, bold, youthful minded, upbeat, media savvy, highly interactive and culturally aware. These are people who may not be currently responding to the breast ...

Breast Cancer : The Risks By Lisa Smedman and Nina K. Tryggvason 1,192 words Are lesbians at higher risk for breast cancer ? In 1993, the queer and mainstream press sounded a dire warning: lesbians had a one in three chance of developing breast cancer ., while the general cancer rate for women is one in nine. The one-in-three rate was derived from a July 1993 by The National Gay and Lesbian Task Force. The paper reported that: lesbians theoretically have a two to three times greater risk of developing breast cancer and gynecologic cancers. It found high incidences of smoking, drinking and weight problems in those aged 50 and up in the sample group and that 75 to 84 per cent of lesbians have a low rate of childbearing, thereby doubling the risk. Heavy alcohol consumption by 25 per cent of lesbians aged 40 and up, increases risk by 1.6. Despite these higher risks, lesbians ...

West Penn Hospital Launches Breast Cancer Support Group West Penn Hospital and the Cancer Caring Center are proud to offer a new support group for breast cancer patients. The group meets at West Penn Hospital on the second Wednesday of each month from 6:30 to 8 p.m. A trained facilitator leads the discussion and sharing and a physician is be available at the beginning of each session to answer questions. Light refreshments and complimentary parking are provided. For more information or to register, please contact the Cancer Caring Center at (412) 622-1212. Workshop Helps Women with Cancer Look Good, Feel Better West Penn Hospital has introduced a new workshop to help female cancer patients look and feel their best during treatment. Look Good Feel Better is a free program sponsored by the American Cancer Society, the Cosmetic, Toiletry and Fragrance Association Foundation, ...

J udy Katz typed her son’s college papers. She buoyed him emo- tionally when organic chemistry caused him to drop his pre-med pro- gram. She encouraged him throughout his law studies. “My mother supported me in everything I did,” Michael B. Katz, JD ’88, states simply. She also left her son a legacy of generosity. “I realized that my mother’s generosity had a life-embracing effect on me,” he says. “She did not teach me how to make a living, but how to live by giving.” Judy Katz was diagnosed with breast cancer when she was 34 and her son, 11. “She never asked, ‘Why me?’ ” says Michael Katz, “She continued to live life by reaching out to help others. For my mom, breast cancer wasn’t about dying; it was just one more reinforcement about living.” After a 17-year remission, the dis- ease returned in 1990. Judy Katz died in ...

breast cancer Visit of the Breast Cancer Alliance of Greenwich to Yale Cancer Center, Tuesday, May 4, 2004 On Tuesday, May 4, 2004, the Breast Cancer Alliance, Inc. of Greenwich will visit Yale Cancer Center for luncheon to hear presentations from physicians and researchers who wish to apply for awards this year. The mission of the Breast Cancer Alliance is to fund innovative breast cancer research and to promote breast health through education and outreach. They provide funding for the following: A diversified portfolio of research with an emphasis on programs that have not yet qualified for Federal monies. Purchase of equipment for research. Breast cancer education and outreach. Since 1997, the Breast Cancer Alliance has awarded over $800,000 ...

Sunday May 23, 2004 8:00 a.m. – 12:00 p.m. East Entrance Steps, Philadelphia Museum of Art All ages and skill levels welcome. All proceeds benefit Living Beyond Breast Cancer ’s education and support programs. Philadelphia Yoga Unites for Living Beyond Breast Cancer A large-scale outdoor yoga class and Healthy Living Expo. Presented by Yoga Unites for Living Beyond Breast Cancer 10 East Athens A ve. Suite 204 Ardmore, P A 19003 NON-PROFIT ORG. US POST AGE PAID Lancaster P A Permit No. 472 Special thanks to the Yoga Unites sponsors whose generous contributions make this program possible. Benefactor Patrons Anonymous (3) In-Kind Sponsors ...

A NATIONAL EDUCATION INITIATIVE Implementation of Guidelines in Breast Cancer A Workshop for Allied Health Professionals and Nurses at St Margaret’s Hospice Education Centre, Clydebank 9am • Monday 5th April 2004 Co-ordinated by: CeNPRaD, The Robert Gordon University, Aberdeen Supported by: SIGN® Endorsed by: NHS QIS and Marie Curie Cancer Care Quality Improvement Scotland THE ROBERT GORDON UNIVERSITY REGISTRATION FORM • Part 2 of 2 AUDIT This education conference focuses on guidelines and audit. In order that we may stay focused in clinical reality we ask for your help by carrying out a brief pre- conference audit: I would be willing to complete an audit relating to breast care services where I work in order to feed into the education day’s workshops. ...

Breast cancer (non-metastatic) Search date October 2002 J Michael Dixon, Kate Gregory, Stephen Johnston, and Alan Rodger What are the effects of treatments for ductal carcinoma in situ? LIKELY TO BE BENEFICIAL Radiotherapy after breast conserving surgery (reduces recurrence) RCTs found that radiotherapy reduced the risk of local recurrence and invasive carcinoma, with no evidence of an effect on survival. Tamoxifen plus radiotherapy after breast conserving surgery (reduces recurrence) One RCT has found that adjuvant tamoxifen significantly reduces breast cancer events in women who have undergone wide excision and radiotherapy, but found no significant difference in overall survival at about 6 years. What are the effects of treatments for operable breast cancer ? BENEFICIAL Adjuvant chemotherapy One systematic review ...

breast cancer Breast Cancer Alliance, Inc. 115 East Putnam Avenue, 2nd Floor Greenwich, CT 06830 203.861.0014 www.breastcanceralliance.org Young Investigator Grant Application 2004 To encourage a commitment to breast cancer research, the Breast Cancer Alliance invites doctors and scientists who are within three years of appointment to an independent position equivalent to Assistant Professor, to apply for funding for the Young Investigator Grant. This grant is open to applicants at institutions in southern New England and the mid-Atlantic states. Mission Statement: The mission of the Breast Cancer Alliance is to fund innovative breast cancer research and to promote breast health through education and outreach. Breast cancer survivors, their friends and health-care professionals are fulfilling this mission. To accomplish this, the Breast ...

breast cancer Breast Cancer Alliance, Inc. 115 East Putnam Avenue, 2nd Floor Greenwich, CT 06830 203.861.0014 www.breastcanceralliance.org Education/Outreach Grant Application 2004 Mission Statement: The mission of the Breast Cancer Alliance is to fund innovative breast cancer research and to promote breast health through education and outreach. Breast cancer survivors, their friends and health-care professionals are fulfilling this mission. To accomplish this, the Breast Cancer Alliance: ? Funds a diversified portfolio of research with an emphasis on programs that have not yet qualified for federal grants ? Funds the purchase of equipment for research and diagnosis ? Provides timely information on breast health and the importance of early detection ? Supports workshops, counseling and free ...

1/2 Press release, 30 march 2004 Breast cancer Discovery of a new tumor marker At the Curie Institute in Paris, CNRS researchers have discovered a new proliferation marker : the CAF-1 complex. Since deregulated cell proliferation is one of the most characteristic features of tumor cells, this discovery represents a breakthrough in the cancer field. The researchers from the Curie Institute have already validated the use of this complex as a tumor marker in the context of breast cancer , the most frequent cancer in women. By combining this marker with other tumor indicators, it will be possible to better characterize tumoral cells and thus to refine diagnosis and develop targeted therapies. These results are published in the April 1 st , 2004 issue of Cancer Research . Cancer is a disease of the cell. Upon accumulation ...