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Key Objectives Following participation in this activity,participants should be able to: 1. discuss new evidence-based diagnostic methods in the field of gastroenterology; 2. describe new technologies,devices,and strategies of treatment; 3. apply recent clinical research findings to practice. Accreditation and Sponsorship This continuing medical education activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of Medical Education Solutions Group (MESG) and the Duke Clinical Research Institute. MESG is accredited by the ACCME to provide continuing medical education for physicians. Colon Cancer Screening Friday,May 5,2006,11 a.m.- 12 p.m.EDT Robert Sandler,MD,MPH Professor of Medicine,Gastroenterology and ...

Introduction Clinical and basic science research programs within the Michael E. DeBakey Department of Surgery continue to raise the standards each year. The success of the individual programs is recognizable through the increases in research funding, publications in quality journals and the international reputation of the department. In order to recognize the accomplishments of these principle investigators, plan our future missions and encourage young investigators, we are presenting the "2005 Molecular Surgeon Research Day," on December 16, 2005. During today’s event, all faculty, surgical residents/fellows, postdoctoral fellows, associates, students and other research staff in the department are invited and encouraged to attend. During the event, our visions, current status and future plans for our research programs will be discussed. Ten principal investigators will receive the "2005 Molecular Surgeon ...

Nebraska Colon Cancer Screening Program Recruitment and Distribution Algorithm Client received EWM enrollment in Clinician’s office, completes the form and sends it to Central Office Client calls Central Office, receives EWM enrollment by mail, enrollment completed and returned to EWM Central Office Client completes Presumptive Enrollment in Clinic; enroll- ment sent to EWM Central Client enrolls in EWM with Outreach; enrollment sent to Central Office NCP enroll- ment and health history sent to client along with let- ter confirming EWM enrollment NCP enrollment and health his- tory for anyone over 50 years in the same house- hold included Health History Assess- ment Referral / Educational Materials Colonoscopy or FOBT Client re- ceives NCP ...

Tobacco Cessation Guideline These clinical guidelines are designed to assist clinicians by providing an analytical framework for the evaluation and treatment of patients. They are not intended to replace a clinician’s judgment or to establish a protocol for all patients with a particular condition. A guideline will rarely establish the only approach to a problem. GUIDELINE HISTORY and APPROVAL ACTION SEED GUIDELINE and/or MAIN INFORMATION & GROUP SOURCE(S) DATE ORGANIZATION Guideline reviewed and approved Treating Tobacco Use and dependence Clinical practice Guideline. U.S. Department of Health and Human Services. June 2000 Website located at: www.surgeongeneral.gov/tobacco/ Sept. 13, 2004 Geisinger Health Plan/ Tobacco Cessation Clinical Guideline Team Guideline reviewed and approved Same as above Sept. 30, ...

Geisinger Health Plan Clinical Guidelines www.thehealthplan.com Page 1 Chronic Obstructive Pulmonary Disease (COPD) Clinical Guideline These clinical guidelines are designed to assist clinicians by providing an analytical framework for the evaluation and treatment of patients. They are not intended to replace a clinician’s judgment or to establish a protocol for all patients with a particular condition. A guideline will rarely establish the only approach to a problem. GUIDELINE HISTORY and APPROVAL ACTION SEED GUIDELINE and/or MAIN INFORMATION & GROUP SOURCE(S) DATE ORGANIZATION Guideline reviewed, revised and approved American Thoracic Society. Statement: Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1995;152(5, pt 2):S77-S121. ...

Geisinger Health Plan Clinical Guidelines www.thehealthplan.com Page 1 Hypertension Clinical Guideline These clinical guidelines are designed to assist clinicians by providing an analytical framework for the evaluation and treatment of patients. They are not intended to replace a clinician’s judgment or to establish a protocol for all patients with a particular condition. A guideline will rarely establish the only approach to a problem. GUIDELINE HISTORY and APPROVAL ACTION SEED GUIDELINE and/or MAIN INFORMATION & GROUP SOURCE(S) DATE ORGANIZATION Guideline Reviewed, Revised and Approved Sixth Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC IV) per National Institute of Health July 5, 2001 Geisinger Health Plan/ Clinical ...

Geisinger Health Plan Clinical Guidelines www.thehealthplan.com Page 1 Acute Low Back Pain Guideline These clinical guidelines are designed to assist clinicians by providing an analytical framework for the evaluation and treatment of patients. They are not intended to replace a clinician’s judgment or to establish a protocol for all patients with a particular condition. A guideline will rarely establish the only approach to a problem. GUIDELINE HISTORY and APPROVAL ACTION SEED GUIDELINE and/or MAIN INFORMATION & GROUP SOURCE(S) DATE ORGANIZATION Guideline reviewed and approved 1.Institute for Clinical Systems Integration (ICSI) Acute Low Back Pain Guideline (Dec 2000 version) 2. Acute Low Back Pain Guideline in Adults. Clinical practice guideline, No. 14. Rockville, MD: U.S. Dept. of Health and Human Services, ...

[ CANCER RESEARCH 64, 3444–3451, May 15, 2004] Telomeric Recombination in Mismatch Repair Deficient Human Colon Cancer Cells after Telomerase Inhibition Oliver E. Bechter, 1 Ying Zou, 2 William Walker, 2 Woodring E. Wright, 2 and Jerry W. Shay 2 1 University of Innsbruck, Department of Internal Medicine, Innsbruck, Austria and 2 University of Texas Southwestern Medical Center, Department of Cell Biology, Dallas, Texas ABSTRACT The majority of human malignancies use telomerase to maintain te- lomere homeostasis. Antitelomerase therapy is therefore a promising approach for a cancer -specific therapy. The alternative lengthening of telomeres pathway (ALT) is a recombination-based, telomerase-independ- ent mechanism of telomere length control. It is widely ...

Na monocarboxylate transport (SMCT) protein expression correlates with survival in colon cancer : Molecular characterization of SMCT Viktoriya Paroder*, Shelly R. Spencer † , Monika Paroder*, Diego Arango ‡ , Simo Schwartz, Jr. ‡ , John M. Mariadason § , Leonard H. Augenlicht § , Sepehr Eskandari † , and Nancy Carrasco* ¶ *Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY 10461; † Biological Sciences Department, California State Polytechnic University, Pomona, CA 91768; ‡ Molecular Oncology and Aging Group, Molecular Biology and Biochemistry Research Center, Valle Hebron Hospital Research Institute, Passeig Valle d’Hebron 119-129, 08035 Barcelona, Spain; and § Department of Oncology, Montefiore ...

OVERLOOK VIEW 3.06 WWW.OVERLOOKVIEW.COM People with inflammatory bowel disease, which causes inflammation of the colon , have a higher risk as well. Other risk factors include being very over- weight and inactive. “Everyone who can should exercise,” says Dr. Levinson. “There’s no question that inactivity as well as obesity are factors for colorectal disease.” Heavy use of alcohol and cigarette smoking are both associated with higher rates of colorec- tal cancer .According to the American Cancer Society, recent studies show that smokers are 30 to 40 percent more likely than non-smokers to die of the disease. Role of diet debated The role of diet in the prevention of col- orectal cancer is somewhat unclear. A recent large federal study of postmenopausal women found that those assigned to a low-fat diet had the same rates of cancer , including colorectal ...

colon cancer 1146 March is Colon Cancer Awareness Month Early Detection Can Mean A Cure When Katie Couric broadcast her own colonoscopy live on the Today Show back in March of 2000, she made Americans aware that early detection of colon cancer can mean a cure. After the broadcast, an initial wave of excitement followed and many people received their first colonoscopy. Without ongoing celebrity endorsement, patient interest in colonoscopy has waned somewhat. Only a third of the people who should be screened for colon cancer get simple tests that can identify colon cancer in its curable stages. Third Leading Cause of Cancer in the U.S. Colon cancer strikes more than 120,000 Americans every year and accounts for 55,000 deaths. It is the third leading cancer in both men (after lung and prostate cancer ) and women (after lung and breast ...

REVISED 7 JUNE 2004 DIRECTORY OF COLON CANCER SPECIALIST TEAMS EASTERN HEALTH AND SOCIAL SERVICES BOARD COLON CANCER UNIT based at BELFAST CITY HOSPITAL & ROYAL GROUP OF HOSPITALS unless otherwise stated Belfast City Hospital - Telephone 028 90 263810 Royal Group of Hospitals - Telephone 028 90 240503 STATUS NAME BASE HOSPITAL Lead Clinician Mr R J Maxwell RHT Specialist Surgeon Mr K Gardiner Mr S T Irwin Mr K Khosraviani Mr V Loughlin Mr A Kennedy Mr D Carey RHT RHT RHT BCH/LVH BCH/LVH BCH Gastroenterologist Dr JSA Collins Dr RGP Watson Dr B Johnston Dr S Johnston RHT RHT RHT BCH Chemotherapy Nurse As per Oncology BCH Radiologist (Lead) Dr B Kelly ...

1672 Main St. Ste. E #264 • Ramona, CA 92065 • Tel: 760.789.8928 • Fax: 760.789.8929 • Toll Free: 800.475.1955 • www.proteinbiotechnologies.com HUMAN COLON CANCER TISSUE ARRAY Catalog Number: TMA-074 Each dot represents a DISEASED tissue spot from one individual specimen that was selected and pathologically confirmed Cases: 80 Cores: 80 Diameter: 1.5mm Thickness: 5 µm Standard IHC: Anti-cytokeratin (CK) antibody confirmed Layout : 8 x 10 1 2 3 4 5 6 7 8 9 10 A 1 2 3 4 5 6 7 8 9 10 B 11 12 13 14 15 16 17 18 19 20 C 21 22 23 24 25 26 27 28 29 30 D 31 32 33 34 35 36 ...

1672 Main St. Ste. E #264 • Ramona, CA 92065 • Tel: 760.789.8928 • Fax: 760.789.8929 • Toll Free: 800.475.1955 • www.proteinbiotechnologies.com HUMAN COLON CANCER TISSUE ARRAY Catalog Number: TMA-068 Each three (3) dots from three different tissue spots represents one single specimen that was pathologically selected and confirmed (Rectum adenocarcinoma tissue array) Cases: 21 Cores: 63 Diameter: 1.5mm Thickness: 5 µm Standard IHC: L-CK confirmed Layout : 7 x 9 1 2 3 4 5 6 7 8 9 A 1 2 3 4 5 6 7 8 9 B 10 11 12 13 14 15 16 17 18 C 19 20 21 22 23 24 25 26 27 D 28 29 30 31 32 33 34 35 ...

1672 Main St. Ste. E #264 • Ramona, CA 92065 • Tel: 760.789.8928 • Fax: 760.789.8929 • Toll Free: 800.475.1955 • www.proteinbiotechnologies.com HUMAN COLON CANCER TISSUE ARRAY Catalog Number: TMA-067 Each three (3) dots from three different tissue spots represents one single specimen that was selected and pathologically confirmed (Rectum adenocarcinoma tissue array) Cases: 21 Cores: 63 Diameter: 1.5mm Thickness: 5 µm Standard IHC: L-CK confirmed Layout : 7 x 9 1 2 3 4 5 6 7 8 9 A 1 2 3 4 5 6 7 8 9 B 10 11 12 13 14 15 16 17 18 C 19 20 21 22 23 24 25 26 27 D 28 29 30 31 32 33 34 35 ...

1 Physician Barriers to Colon Cancer Screening Several studies have demonstrated that physician recommendation is a powerful predictor of colon cancer screening. 1-3 In Washington State, having discussed colon cancer screening with a physician significantly increased the odds of being up-to-date for colon cancer screening. 4 Despite the power of physician recommendations, colon cancer screening rates are low. Physicians and other healthcare providers face multiple barriers to colon cancer screening. In this report, we discuss recent literature concerning these barriers, including physician knowledge, practice characteristics, and patient factors. Physician Knowledge A recent survey of internal medicine residents, internal medicine attendings, and medical students revealed that knowledge of American Cancer Society (ACS) colon cancer screening ...

Assay Validation for Identification of Hereditary Nonpolyposis Colon Cancer -Causing Mutations in Mismatch Repair Genes MLH1 , MSH2 , and MSH6 Madhuri Hegde,* Maria Blazo,* Belinda Chong,* Tom Prior, † and Carolyn Richards* From The Diagnostic Sequencing Laboratory, * Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas; and the Ohio State University, † Department of Pathology, Columbus, Ohio Hereditary nonpolyposis colon cancer (HNPCC, On- line Mendelian Inheritance in Man (OMIM) 114500) is an autosomal dominant disorder that is genetically heterogeneous because of underlying mutations in mismatch repair genes, primarily MLH1 , MSH2 , and MSH6 . One challenge to correctly diagnosing HNPCC is that the large size of the causative genes makes identification of mutations both labor ...

1672 Main St. Ste. E #264 • Ramona, CA 92065 • Tel: 760.789.8928 • Fax: 760.789.8929 • Toll Free: 800.475.1955 • www.proteinbiotechnologies.com HUMAN COLON CANCER TISSUE ARRAY Catalog Number: TMA-059 Each three (3) dots from three different tissue spots represents one single specimen that was selected and pathologically confirmed ( Colon Adenocarcinoma tissue array) Cases: 23 Cores: 63 Diameter: 1.5mm Thickness: 5 m Standard IHC: L-CK confirmed Layout : 7 x 9 1 2 3 4 5 6 7 8 9 A 1 2 3 4 5 6 7 8 9 B 10 11 12 13 14 15 16 17 18 C 19 20 21 22 23 24 25 26 27 D 28 29 30 31 32 33 ...

1672 Main St. Ste. E #264 • Ramona, CA 92065 • Tel: 760.789.8928 • Fax: 760.789.8929 • Toll Free: 800.475.1955 • www.proteinbiotechnologies.com HUMAN COLON CANCER TISSUE ARRAY Catalog Number: TMA-051 Each dot represents a DISEASED tissue spot from one individual specimen that was selected and pathologically confirmed ( colon carcinoma tissue array) Cases: 70 Cores: 72 Diameter: 1.5mm Thickness: 5 m Standard IHC: L-CK confirmed Layout : 8 x 9 1 2 3 4 5 6 7 8 9 A 1 2 3 4 5 6 7 8 9 B 10 11 12 13 14 15 16 17 18 C 19 20 21 22 23 24 25 26 27 D 28 29 30 31 32 33 34 35 ...

1672 Main St. Ste. E #264 • Ramona, CA 92065 • Tel: 760.789.8928 • Fax: 760.789.8929 • Toll Free: 800.475.1955 • www.proteinbiotechnologies.com HUMAN COLON CANCER TISSUE ARRAY Catalog Number: TMA-050 Each dot represents a DISEASED tissue spot from one individual specimen that was selected and pathologically confirmed ( colon carcinoma tissue array) Cases: 70 Cores: 72 Diameter: 1.5mm Thickness: 5 m Standard IHC: CEA confirmed Layout : 8 x 9 1 2 3 4 5 6 7 8 9 A 1 2 3 4 5 6 7 8 9 B 10 11 12 13 14 15 16 17 18 C 19 20 21 22 23 24 25 26 27 D 28 29 30 31 32 33 34 35 ...

1672 Main St. Ste. E #264 • Ramona, CA 92065 • Tel: 760.789.8928 • Fax: 760.789.8929 • Toll Free: 800.475.1955 • www.proteinbiotechnologies.com HUMAN COLON CANCER TISSUE ARRAY Catalog Number: TMA-066 Each three (3) dots from three different tissue spots represents one single specimen that was selected and pathologically confirmed (Rectum adenocarcinoma tissue array) Cases: 21 Cores: 63 Diameter: 1.5mm Thickness: 5 m Standard IHC: L-CK confirmed Layout : 7 x 9 1 2 3 4 5 6 7 8 9 A 1 2 3 4 5 6 7 8 9 B 10 11 12 13 14 15 16 17 18 C 19 20 21 22 23 24 25 26 27 D 28 29 30 31 32 33 ...

1672 Main St. Ste. E #264 • Ramona, CA 92065 • Tel: 760.789.8928 • Fax: 760.789.8929 • Toll Free: 800.475.1955 • www.proteinbiotechnologies.com HUMAN COLON CANCER TISSUE ARRAY Catalog Number: TMA-065 Each three (3) dots from three different tissue spots represents one single specimen selected and pathologically confirmed (Rectum adenocarcinoma tissue array) Cases: 22 Cores: 72 Diameter: 1.5mm Thickness: 5 m Standard IHC: CEA confirmed Layout : 8 x 9 1 2 3 4 5 6 7 8 9 A 1 2 3 4 5 6 7 8 9 B 10 11 12 13 14 15 16 17 18 C 19 20 21 22 23 24 25 26 27 D 28 29 30 31 32 33 34 ...

Source: American College of Gastroenterology (ACG) Released: Wed 14-Apr-2004, 08:00 ET Colon Cancer Expert: Comment on New Virtual Colonoscopy Study Libraries Medical News Keywords COLORECTAL CANCER , COLONOSCOPY, CT COLONOGRAPHY Contact Information Available for logged-in reporters only DescriptionExpert on colonoscopy and colorectal cancer screening Douglas K. Rex, M.D., President of the ACG and a co-author of today's new study in JAMA on CT colonography is available to discuss findings. Newswise — Findings of a new multicenter study by Cotton et al. published today in the Journal of the American Medical Association comparing standard colonoscopy with CT colonography for the detection of colorectal cancer reveal that this technology, in the form used most often in the United States, while of significant interest, is not presently a viable option ...

Metastasis of colon cancer cells reversed in vitro P UBLIC RELEASE DATE : 5-J AN -2004 Contact: Alex Smith Alex_smith@margeotes.com 212-460-0563 Weizmann Institute Weizmann Institute scientists have succeeded in reversing the metastatic properties of colon cancer cells, in vitro. The findings, published in the Nov. 24 issue of The Journal of Cell Biology, uncover a key process involved in the metastasis of colon cancer cells and raise hopes that target-specific drugs might be devised to prevent, or reverse, the invasive behavior of metastatic colon cancer cells. Colon cancer is the second most prevalent type of cancer in men and third in women in the Western world. The researchers, headed by Prof. Avri Ben-Ze'ev of the Molecular Cell Biology Department, have confirmed that the invasive behavior of colon cancer ...

Chiang Mai Med Bull 2005;44(1):21-28. Original article C ENTELLA A SIATICA EXTRACT INDUCES CELL CYCLE ARREST IN CACO-2 HUMAN COLON CANCER CELLS Piyawan Bunpo, 1,2 B.Sc., Keiko Kataoka, 2 Ph.D., Hideki Arimochi, 2 Ph.D., Haruyuki Nakayama, 2 M.Sc., Tomomi Kuwahara, 2 Ph.D., Yoshinari Ohnishi, 2 Ph.D., Usanee Vinitketkumnuen, 1 Ph.D. 1 Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand, 2 Department of Molecular Bacteriology, Graduate School of Medicine, The University of Tokushima, Tokushima, Japan 770-8503 Abstract Centella asiatica is traditionally a medicinal plant frequently employed in the practice ...