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MEDIA ADVISORY: For Tuesday, March 18 th NEW FINDINGS ON COLON CANCER SCREENING TO BE RELEASED Contact: Kathryn Cervino, Associate Director of Communications 212.822.7285 kcervino@nyam.org WHAT: Important new findings regarding colon cancer screening in New York City, especially among minority populations, will be presented by the New York’s leaders in public health, health care and medical research. WHEN: Tuesday, March 18, 2003 10:00 a.m. Contact: Sandra Mullin, Associate Commissioner Office of Communications 212.788.5290 smullin@health.nyc.gov WHERE: Harlem Hospital – enter at 506 Lenox Avenue (at 135 th Street) Auditorium on 2nd Floor of Martin ...

I n the general population, renal cell carcinoma accounts for 90% of upper uri- nary tract cancers, whereas urothelial tumors account for only about 5%. 1 Certain environmental toxins are thought to be etiologic in the development of urothelial tumors, most notably smoking and exposure to certain amine-based chemicals. Although a familial tendency to develop upper tract urothelial car- cinomas has been previously noted, most cases are thought to be acquired and not inherited. 2-4 C ASE R EVIEW Urothelial Carcinoma in a Man with Hereditary Nonpolyposis Colon Cancer Dean L. Lenz, MD, Lewis E. Harpster, MD Department of Surgery, Division of Urology, Pennsylvania State University, Milton S. Hershey Medical Center, Hershey, PA Although most upper tract urothelial carcinomas are believed to be acquired, ...

March 2003 A publication of the Sentara Cancer Institute at Sentara Norfolk General Hospital for patients, physicians and health care professionals The Truth About Colon Cancer News of celebrities being diagnosed with colon cancer is sometimes a hot news topic. And while public attention is good for raising awareness of the disease, it may sometimes be difficult to sort out fact from fiction . For clarification, the top six colon cancer misconceptions are addressed below. Myth #1: Only men get colon cancer . Colon cancer is sometimes considered a man’s disease however; both men and women can develop colon cancer . Colon cancer does not discriminate between the sexes. Myth #2: Old people get colon cancer . Even though, most people diagnosed with colon cancer are over the age of 65, there are ...

Clinical Guideline: Colon Cancer Screening Introduction There is good evidence to support screening average risk individuals for colon cancer . Screening should be implemented beginning at age 50 for average risk individuals. Three randomized controlled trials have demonstrated reduced mortality from colon cancer with fecal occult blood testing programs (See references 3, 4, and 5). No randomized clinical trial has yet been reported using flexible sigmoidoscopy, however this screening method appears promising when used at 5 year intervals. Guideline Statement Univera recommends colon cancer screening of all average risk members age 50 through 80. After the age of 80, it will be at physician and patient discretion. The following screening methods are recommended: · Annual Fecal Occult Blood Testing (FOBT) OR · Flexible Sigmoidoscopy every 5 years OR ...

1 Pre-publication history 6 April 2001 Original version submitted A combined analysis of the Deleted in Colon Cancer (DCC) and the p53 proteins expression in gastric cancer . Francesco Graziano [ frada@tin.it] Stefano Cascinu [ cascinu@yahoo.com] Maria Pia Staccioli [ oncops@yahoo.com] Vincenzo Catalano [ catalano@yahoo.it ] Maria Cristina Rossi [ oncops@yahoo.com] Anna Maria Baldelli [ oncops@yahoo.com] Paolo Giordani [ oncops@yahoo.com] Pietro Muretto [ oncops@yahoo.com] Giuseppina Catalano [ oncops@yahoo.com] Title: A combined analysis of the Deleted in Colon Cancer (DCC) and the p53 proteins expression in gastric cancer . Running head : DCC and p53 expression in gastric cancer ...

Colon and Rectum Cancer N Rate N Rate N Rate Male All Races 31820 54.5 3601 47.8 737 45.3 Non-Hisp. White 26810 54.2 3097 47.2 627 44.7 Hispanic NA NA 346 53.1 79 53.8 Black 2559 60.1 112 55.5 22 50.3 Female All Races 31247 38.2 3544 34.5 757 34.3 Non-Hisp. White 26469 37.7 3147 34.7 664 34.5 Hispanic NA NA 250 31.0 58 32.0 Black 2794 45.6 110 41.0 17 29.4 1 USA rates are from NCI SEER program; USA rates for "Non-Hisp. White" category include Hispanic white. Rate is significantly higher than rate in column to its left. Rate is significantly lower than rate in column to its left. ...

New York State Department of Health 1999 The New York State Cancer Surveillance Improvement Initiative Cancer of the Colon and Rectum among Males and Females 1992-1996 Page 2 The NYS Cancer Surveillance Improvement Initiative What is the New York State Cancer Surveillance Improvement Initiative? In April 1998, Governor George E. Pataki asked the State Health Department to develop easy to understand information that would help answer people’s questions about the number of cancer cases in their communities. The Health Department started the Cancer Surveillance Improvement Initiative in response to the Governor’s request. The maps and information in this booklet are from that project. Words marked in bold are defined at the side of each page. The project includes many ...

Colon cancer is the second leading cause of cancer -related deaths, after lung cancer , in the United States. An estimated 148,300 new cases and 56,600 deaths from colorectal cancer are expected in the United States in 2002. The lifetime risk of colon cancer for a US citizen, male or female, is about 5-6 percent. What is a polyp? Colon cancer begins as a polyp, a growth of tissue in the inner lining What should I know about colon cancer ? F a l l 2 0 0 2 W h a t ’s I n s i d e : 1 W h a t s h o u l d I k n o w a b o u t c o l o n c a n c e r ? 3 D i f f e r e n t s c r e e n i n g t o o l s h e l p c a t c h c a n c e r e a r l y 4 R e d u c e y o u r r i s k o f c o l o n c a n c e r 5 W h a t t o e x p e c t f r o m a ...

H E L P I N G Y O U L E A R N M O R E A B O U T Y O U R H E A L T H Colon Cancer Colon cancer is the third most commonly diag- nosed cancer among American men and women and the third leading cause of cancer death. According to the American Cancer Society, about 98,200 cases will be diagnosed in the U.S. this year and 48,100 people will die from it. Colon cancer is more common after age 50, in people with a family history of the cancer , patients with chronic inflammatory bowel disease, and those who are obese, inactive, or have a high fat diet. Most colon cancers develop from tiny growths known as adenomatous polyps, or adenomas. Although these polyps are not cancerous themselves, having them ...

A family with colon cancer : genetic testing and decision-making David Yandell ScD January 2003 Copyrighted October 4, 2000 This case was developed for use in the Integrated Genetics, Epidemiology, Ethics Program for the University of Vermont College of Medicine. Sale or publication without the permission of the University of Vermont College of Medicine is prohibited. 11/23/01 1 Page 2 A Family with Colon Cancer : Testing and Decision-making Goal: Using familial colon cancer as a model, examine the key issues of testing for genetic predisposition to disease in high-risk individuals and family members. References : Solomon, et al. Current Status of Genetic Testing for Colorectal Cancer Susceptibility. Oncology, 2002; 16(2): 162-180. Nassbaum, McInnes, Willard. Genetics in Medicine. Thompson & Thompson, 6 ...

page 1 of 2 All images and text in this document are the sole property of the University of Maryland. For more information contact the Office of the Associate Director, 301.405.2462 (MAES) Maryland Agricultural Experiment Station 1201 Symons Hall, University of Maryland, College Park, MD 20742 “Maryland Dividends” Maryland Agricultural Experiment Station College of Agriculture & Natural Resources Premiums returned on investments in research, education and outreach. 19 December 2002 magnuson2 For more information about this research project please contact: Bernadene Magnuson Assistant Professor Nutrition and Food Sci 3301 Marie Mount Hall, Univ of Maryland College Park, MD, 20472 301.405.4523 bm150@umail.umd.edu Research Team: Dr. Bernadene Magnuson (U of M), Youngjoo Kwon (U of M), and Dr. Minnie Malik (U of M), and Dr. ...

Corporate Medical Policy Colon Cancer Screening File Name: colon_cancer_screening Policy Number: SUR6164 Origination: 12/2000 Last Review: 6/2002 Next Review: 6/2004 Description of Procedure or Service When colorectal cancer is diagnosed at an early, localized state, five-year survival is 90%, yet only 37% of incident cases are diagnosed while still localized. The same methods used to detect colorectal cancers at early, curable stages can also identify and remove adenomas, which give rise to colorectal cancer . Methods for early detection can therefore actually prevent colorectal cancer . Definitions of Early Detection Methods are as follows: ? Fecal Occult Blood Test (FOBT) - FOBT is a laboratory procedure that refers to the implementa- tion of the protocol for collecting and testing six samples from three consecutive stools ...

Colon Cancer Complementary Therapy: Suggested Supplementation If you have any questions regarding your treatment options, contact your Physician or Oncologist. To review the complete Colon Cancer Complementary Therapy, visit http://www.canceroption.com ImmuneOption 2 scoops, in water or juice, 3 times daily with meals (6 scoops total a day) BETAGlucan CAOP 1 capsule, 3 times daily, take 30 minutes before meals (3 capsules total a day) ImmuneEssential CAOP 3 drops, sublingual for 5 minutes, 7 times daily (Oral - refrigerate bottle) (21 drops total a day; use applicator) FloraPlusOption ½ teaspoon, 1 time a day in pure water, individuals (refrigerate bottle) experiencing diarrhea may take 2 to 3 times a day (1½ teaspoons total a day) Vita-C Option 3 to 8 rounded teaspoons (6,000 to 16,000 mg) in 32 ounces of purified ...

Colon and Rectal Cancer Treatment Guidelines for Patients Version II / June 2002 Page 2 The mutual goal of the National Comprehensive Cancer Network (NCCN) and the American Cancer Society (ACS) partnership is to provide patients and the general public with state-of-the- art cancer treatment information in understandable language. This information, based on the NCCN’s Clinical Practice Guidelines, is intended to assist you in the dialogue with your doctor. These guidelines do not replace the expertise and clinical judgment of your doctor. Each patient’s situation must be evaluated individually. It is important to discuss the guidelines and all infor- mation regarding treatment options with your doctor. To ensure that you have the most up-to- date version of the guidelines, consult the Web sites of the ACS (www. cancer .org) or NCCN (www.nccn.org). ...

HEALTH STATUS INDICATOR PROJECT ~ A PROJECT OF THE HEALTH CARE COST SUMMIT 40 21. Colon Cancer Death Rate Table 21A: Average Annual Five Year Age-Adjusted** Death Rates Location Indicator 1990-1994 1991-1995 1992-1996 1993-1997 1994-1998 1995-1999 1996-2000 Erie City Total Age-Adjusted Rate 20.8 20.1 20.6 20.3 20.5 19.8 20.3 Total White Age-Adjusted Rate 20.2 20.0 21.1 21.2 21.5 20.5 21.4 Total Black Age-Adjusted Rate 27.6 15.7 7.7 5.4 6.9 8.7 5.6 Erie County Total Age-Adjusted Rate 21.2 19.6 19.2 17.9 18.6 17.0 17.7 Total White Age-Adjusted Rate 21.0 19.6 19.4 18.2 19.0 17.3 18.1 Total Black Age-Adjusted Rate 22.6 10.4 4.1 2.0 3.2 4.9 4.8 Pennsylvania Total Age-Adjusted Rate 23.2 22.7 22.5 21.9 21.5 21.2 -- White Age-Adjusted Rate 22.9 22.4 22.2 21.6 21.2 ...

About Colon Cancer By Jefferson Hurley, M.D. Colon cancer , uncontrolled growth of harmful cells in the large intestine, is the second leading cause of cancer deaths in the United States. Although the occurrence of colon cancer is quite high, it is a largely preventable disease. The following steps can be taken to help identify your risk of colon cancer . The first step to conquering colon cancer is to know its associated risk factors: ? Age greater than 50 years ? Personal or family history of colon cancer , polyps, or inflammatory bowel disease ? Prior endometrial, ovarian or breast cancer ? Eating a high-fat and a low-fiber diet The second step is to be able to identify the signs and symptoms: ? Rectal bleeding ? Blood in the stool ? Change in bowel habits (pain, frequent constipation) If you experience ...

(over) colorectal, detection, rectal Cancer of the Colon and Rectum The lower portion of the digestive system is the colon . It also is called the large bowel or large intestine. The colon is the last 5 to 6 feet of the intestine. The last 8 to 10 inches of the colon is the rectum. After food is digested, solid wastes move through the colon and rectum to the anus, where they are passed out of the body. Symptoms: When disease affects the colon or rectum, several symptoms may appear. A person should see a doctor if any of these symptoms last two weeks or longer. C Diarrhea or constipation C Stools that are narrower than usual C Bloating, fullness or cramps C Frequent gas pains C Loss of weight for no reason C Constant tiredness C Blood in or on the stool (bright red or very dark red) ...

Colorectal cancer is the second leading cause of cancer deaths in the United States. It generally strikes men and women over age 50, and often has no symptoms. The good news is that early detection through colorectal screening could save your life! The SuburbanHospital Healthcare SystemandMobile Medical Care, Inc. (MobileMed) are workingwiththe Montgomery County Cancer Crusade, anewprogramdevelopedthroughtheStateof Maryland'sCigaretteRestitutionFundProgram.Thegoal istohelpcombatcancer anddecrease the burdenof tobacco-relateddiseases, particularlyinuninsuredor medicallyunder-servedpopulations. Individuals whomeet certainfinancial eligibilityrequirements may receive free evaluations, screeningandfollow-uptreatment. Tolearnmore, please call SuburbanOn-Call at (301) 896-3939, option1. Get a check up. Your life maydependonit. Male or female over age 50? Family or personal history? ...

colon cancer "Virtual colonoscopy" brings comfort to colon cancer surveillance 11/01/01 By: Reuters Health By Pam Harrison LISBON (Reuters Health) - A "virtual colonoscopy" procedure has arrived that is far more satisfactory to colorectal cancer patients than traditional colonoscopy. Dr. Enilio Bria, a fellow in medical oncology at the University of Rome, and colleagues followed patients who had previously undergone surgical excision of colorectal cancer , performing spiral CT examinations over 3 years. "[Previously] p atients were being followed with a schedule that consisted of annual conventional colonoscopy, liver ultrasound and chest-X ray," the investigators note. Their findings were presented here during the European Cancer Conference. During the standard spiral CT examinations, images of the thorax, the abdomen and the pelvis were captured as patients alternated ...

Case #4 Sentinel Node Biopsy in Colon Cancer David M. Ota, MD, FACS Milwaukee, WI Page 2 65 yo female with sigmoid adenoca. CXR, liver US and CEA are normal. Sigmoid colectomy done and final path report shows T3 with 6 negative lymph nodes(T3N0M0). Page 3 Pathologic Understaging of CRC reality or fiction? Page 4 Colon Cancer 5 yr survival stage I 90-95% stage II 80% stage III 50-60% Page 5 Stage II Colon Ca 1016 pts in 5 adjuvant trials 5 yr survival obs 80% FU+LV 82% Impact Invest JCO 1999 Page 6 Stage III improved survival with FU+LV Some Stage II are understaged Page 7 Standard Technique ...

USC CLINICAL GENETICS UNDERSTANDING YOUR FAMILY HISTORY OF COLON CANCER UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE DEPARTMENT OF OBSTETRICS AND GYNECOLOGY DIVISION OF GENETICS Location: Two Medical Park Suite 301 Columbia, SC 29203 Phone: 803-779-4928 ext. 228 Toll free in SC: 800-544-9866 Fax: 803-434-6852 (laboratory) Fax: 803-434-4596 (genetic counselors) E-mail: uscgenetics@medpark.sc.edu Web: www.med.sc.edu/uscgenetics 13 C olorectal cancer is the third most common cancer diagnosed in the United States. In 2000 alone, an estimated 135,000 new cases were diagnosed. The chance that a person will develop colorectal cancer in his or her lifetime approaches 6%. Family History: Most cases of colorectal cancer occur by chance in individ- ...

colon cancer BIOL 207 Biology of Cancer 3/18/02 Lecture 14: " Colon Cancer " Reading: Scientific American special issue pp. 92-93 Lecture: 1. Risk factors 2. Screening tests 3. Hereditary diseases associated with colon cancer Path of digestion (organ system handout--digestive system) mouth pharynx esophagus stomach small intestine large intestine ( colon , rectum, anus) Colon cancer : Primary tumor colon or rectum, secondary tumor usually liver. Second leading cancer killer after lung cancer . Risk factors: heredity ~10% of cases presence of polyps= benign growths in intestinal lining smoking colitis or Crohn?s disease (diseases of GI tract) industrial or urban area? ...

HERBS/SUPPLEMENTS FOR COLON CANCER TREATMENT/PREVENTION BARLEY: Likely effective when used orally for reducing blood cholesterol, lipid and sugar levels, and reducing the risk of colon cancer . The fiber content of barley is responsible for the observed reduction of cholesterol levels in healthy and hypercholesterolemic people, the reduction of blood sugar and insulin levels in healthy people, and the reduction of the colon cancer risk in rats (6). BETA-CAROTENE: Beta-carotene is safe for most people when used in doses up to 300 mg per day (14,15). However, higher doses are more likely to cause side effects such as yellowing of the skin (9). POSSIBLY UNSAFE when used orally in people who smoke. Beta-carotene 20 mg daily for 5-8 years seems to increase the risk of lung and prostate cancer , intracerebral hemorrhage, and cardiovascular and total mortality in people who smoke ...

[ CANCER RESEARCH 62, 1030–1035, February 15, 2002] Circulating Insulin-like Growth Factor-I Levels Regulate Colon Cancer Growth and Metastasis Yiping Wu, Shoshana Yakar, Ling Zhao, Lothar Hennighausen, and Derek LeRoith 1 Section of Cellular and Molecular Physiology, Cellular Endocrinology Branch [Y. W., S. Y., D. L.] and Laboratory of Genetics and Physiology [L. Z., L. H.], National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, Maryland 20892-1758 ABSTRACT It has been shown previously that slight elevations in serum levels of insulin-like growth factor-I (IGF-I) are correlated with an increased risk for developing prostate, breast, colon , and lung cancer . The aim of this study was to determine the role of serum IGF-I levels in the process of stimulating tumor growth and metastasis in a mouse model of colon cancer ...