AllDocs -> cancers

FRIDAY Joint Symposium: MOGA / ANTIGER Neuroendocrine Tumours – Recent Advances in DIAGNOSIS AND Management 18 Neuroendocrine GEP-tumors: Advances in Diagnosis and Treatment By Kjell Öberg, M.D., Ph.D. Professor Endocrine Oncology Dept. of Endocrine Oncology, Uppsala University Hospital, Uppsala, Sweden Neuroendocrine tumors of the gastrointestinal tract and pancreas constitute about 2 % of all malignant tumors. They include a number of different tumors, derived from cells of the diffuse neuroendocrine cell-system. The largest group of neuroendocrine tumors are the so called carcinoids with an incidence of about 2.5/100 000 per year. The old classification of neuroendocrine GEP-tumors is based on the embryonic origin, but there is a new WHO- classification taking into the consideration the tumor biology of different subtypes of neuroendocrine tumors. The tumors exhibit substantial differences in ...

cancer 1581 Wharton Department of Statistics Data Mining Bob Stine Department of Statistics www-stat.wharton.upenn.edu/~bob Wharton Department of Statistics 2 Overview Applications Marketing: Direct mail advertising (Zahavi example) Biomedical: finding predictive risk factors Financial: predicting returns and bankruptcy Role of management Setting goals Coordinating players Critical stages of modeling process Picking the model <-- My research interest Validation Wharton Department of Statistics 3 Predicting Health Risk Who is at risk for a disease? Costs False positive: treat a healthy person False negative: miss a person with the disease Example: detect osteoporosis without need for x-ray ...

GASTROINTESTINAL CANCER Prof. Dr. M. Peeters Dept of Gastroenterology/Oncology University Hospital Ghent On this thirty-ninth annual meeting of the American Society of Clinical Oncology in Chicago, Illinois, 524 abstracts on Gastrointestinal Cancer (GI) were published in the abstract book. Approximately 170 GI cancer papers were, either orally or as poster, presented at the meeting itself. Not only was the quantity excellent. Also the quality was outstanding this year. Mature data from several large, randomized trials became available and were discussed. For example, convincing results on the role of novel agents in the treatment of metastatic colorectal cancer were presented. The conclusions will certainly influence our clinical practice in the near future. It was absolutely necessary to make a selection in the presented material for this paper. We decided ...

Web Immagini Gruppi Directory News altro » Ricerca avanzata Preferenze Cerca nel Web Cerca solo le pagine in Inglese Spiacenti, nessun contenuto associato a questo URL Web La ricerca di - cache:ZQbbGkEQLGcJ:www.jsps.go.jp/j-grantsinaid/12_kiban/gaiyo_17/data/en/se17_imai_en.pdf gastrointestinal cancer filetype:pdf OR filetype:doc OR filetype:ppt OR filetype:xls OR filetype:rtf - non ha prodotto risultati in nessun documento. Suggerimenti: Assicurarsi che tutte le parole siano state digitate correttamente. Provare con parole chiave diverse. Provare con parole chiave più generiche. Provare con ...

Several recent longitudinal studies have reported an association between various markers of periodontal disease and heart disease. 1 The association between periodontal disease and stroke has also been examined. 2 Although a majority of these studies found a positive association between poor oral health and cardiovascular diseases, study limitations have raised questions regarding the nature of this association. Specifically, authors have raised concerns that rather than periodontal disease being a true risk factor, the findings are due to the inadequate measurement of and control for tobacco smoking history. 3 Since smoking is strongly correlated with both periodontal and heart disease, residual confounding could produce falsely elevated risk estimates. In addition, several authors have cited the imprecision and subjective nature of the measurements used ...

Novartis International AG Novartis Communications CH-4002 Basel Switzerland Tel + 41 61 324 2200 Fax + 41 61 324 3300 Internet address: http://www.novartis.com *In the US: Gleevec ® (imatinib mesylate) 1/2 MEDIA RELEASE • COMMUNIQUE AUX MEDIAS • MEDIENMITTEILUNG Glivec ® approved in Japan for treatment of life-threatening gastrointestinal cancer Basel, Switzerland, 17 July 2003 – Novartis announced today that health authorities in Japan have approved Glivec ® (imatinib)* for the treatment of patients with KIT (CD117) positive gastrointestinal stromal tumors (GISTs), a life-threatening cancer . Historically, GISTs have been very difficult to treat due to their resistance to treatment with available chemotherapy and radiation therapy. Previously, surgery ...

Novartis International AG Novartis Communications CH-4002 Basel Switzerland Tel + 41 61 324 2200 Fax + 41 61 324 3300 Internet address: http://www.novartis.com *In the US: Gleevec ® (imatinib mesylate) 1/2 MEDIA RELEASE • COMMUNIQUE AUX MEDIAS • MEDIENMITTEILUNG Glivec ® approved in Japan for treatment of life-threatening gastrointestinal cancer Basel, Switzerland, 17 July 2003 – Novartis announced today that health authorities in Japan have approved Glivec ® (imatinib)* for the treatment of patients with KIT (CD117) positive gastrointestinal stromal tumors (GISTs), a life-threatening cancer. Historically, GISTs have been very difficult to treat due to their resistance to treatment with available chemotherapy and radiation therapy. Previously, surgery was ...

PO Box 2345, Beijing 100023, China World J Gastroenterol 2006 February 7; 12(5):815-817 www.wjgnet.com World Journal of Gastroenterology ISSN 1007-9327 wjg@wjgnet.com © 2006 The WJG Press. All rights reserved. CASE REPORT Small gastrointestinal stromal tumor concomitant with early gastric cancer : A case report Ying-Lung Lin, Jeh-En Tzeng, Chang-Kou Wei, Chih-Wen Lin www.wjgnet.com Ying-Lung Lin, Jeh-En Tzeng, Chang-Kou Wei, Chih-Wen Lin, Department of Family Medicine, Pathology, General Surgery, Radiology, Buddhist Dalin Tzu Chi General Hospital, Chia Yi, Taiwan, China Correspondence to: Dr Jeh-En Tzeng, Department of Pathology, Buddhist Dalin Tzu Chi General Hospital, 2, Min Sheng Road, Dalin, Chia Yi, Taiwan, China. p121521@tzuchi.com.tw Telephone: +886-5-2648000-5725 Received: 2005-06-07 Accepted: 2005-08-03 Abstract ...

07. Gastrointestinal Cancer including Liver OP170 LOSS OF THE „COXSACKIE UND ADENOVIRUS RECEPTOR (CAR)“ EXPRESSION CORRELATES WITH POOR CLINICAL OUTCOME, TUMOR DEDIFFERENTIATION, INCREASED PROLIFERATION, AND OCCURRENCE OF DISTANT METASTASIS IN GASTRIC ADENOCARCINOMAS Anders, M. 1 ; Vieth, M. 3 ; Koschel, A. 1 ; Wiedenmann, B. 2 ; Röcken, C. 4 ; Ebert, M. 5 ; Kemmner, W. 6 ; Höcker, M. 1 1 Laboratory for Angiogenesis and Tumor Metastasis, Charité, Campus Virchow-Klinikum, Berlin; 2 Department of Internal Medicine, Divisions of Gastroenterology and Hepatology, Charite Medical School - Campus Virchow, Berlin; 3 Institut für Pathologie, Bayreuth; 4 Otto-von-Guericke-Universität, ...

07. Gastrointestinal Cancer including Liver OP171 ROLE OF SRC-FAMILY KINASES IN GASTROINTESTINAL STROMAL TUMORS Bauer, S. 1 ; Demetri, G.D. 3 ; Fletcher, J.A. 2 1 Westdeutsches Tumorzentrum, Universitätsklinikum, Essen; 2 Brigham & Womens Hospital, Harvard Medical School, Boston, MA, USA; 3 Dana Farber Cancer Institute, Boston, MA, USA Background: Inhibition of KIT oncoproteins by imatinib mesylate (IM) induces clinical responses in most GIST patients. However, many patients develop IM-resistance due to secondary KIT mutations and none of the novel KIT inhibitors inhibits all known IM-resistance mutations. Src-family kinases (SFK) are important signaling intermediates in related kinase-driven tumor models (ALL, CML) and dual-specific Src/Abl-inhibitors show promising activity in IM-resistant ...

07. Gastrointestinal Cancer including Liver OP169 COMBINATION ANALYSIS OF ACTIVATOR PROTEIN-1 FAMILY MEMBERS, SP1AND AN ACTIVATOR PROTEIN-2 ? -RELATED FACTOR BINDING TO DIFFERENT REGIONS OF THE UROKINASE RECEPTOR (U-PAR) GENE IN RESECTED COLORECTAL CANCERS Schewe, D. 1 ; Biller, T. 2 ; Maurer, G. 3 ; Assangani, I. 2 ; Leupold, J. 2 ; Lengyel, E. 4 ; Post, S. 5 ; Allgayer, H. 2 1 Dr. von Haunersches Kinderspital, Ludwig-Maximilians-Universität, München; 2 Abteilung für experimentelle Chirurgie und Molekulare Onkologie, Universitätsklinikum, Mannheim; 3 Chirurgische Klinik Grosshadern, Ludwig-Maximilians-Universität, München; 4 Department of Obstetrics and Gynecology, University ...

07. Gastrointestinal Cancer including Liver OP168 EGFR REACTIVATES TELOMERASE IN IMMORTALIZED SQUAMOUS EPITHELIAL CELLS THROUGH PI3K/AKT-MEDIATED PHOSPHORYLATION AND TRANSCRIPTIONAL REGULATION VIA HIF-1ALPHA Heeg, S. 1 ; Heeg, S. 1 ; von Werder, A. 1 ; Doebele , M. 1 ; Quante, M. 1 ; Scheffer, E. 1 ; Goessel, G. 1 ; Fulda, C. 1 ; Kunert , H. 1 ; Nakagawa, H. 2 ; Beijersbergen, R. 3 ; Blum, H.E. 1 1 Medizinische Klinik, Universität, Freiburg; 2 Gastroenterology Division, University of Pennsylvania, Philadelphia, PA, USA; 3 Netherlands Cancer Center, Amsterdam, Netherlands Introduction: In our cellular model ...

Summer 2005 Issue 1 Gastrointestinal Cancer Rapid Medical Donation Program Newsletter Inside: Meet The Lab 2 Participant Family Corner 3 Contact Information 4 Related Programs - NFPTR 6 Related Programs - Breast Cancer Medical Donation 6 The Johns Hopkins University School of MedicineKnowledge, For The World I write to you today with two goals-to introduce both myself and my laboratory to you, and to provide an update of the tremendous impact your loved one has made by participating in the Johns Hopkins Gastrointestinal Cancer Rapid Medical Donation Program (GICRMDP). Who am I? Born and raised in Bayshore, New York, I learned at the early age of 10 how devastating a cancer diagnosis can be when my father passed away of advanced colorectal cancer . When he was diagnosed, the cancer had already ...

gastrointestinal cancer 1126 6Th FRAMEWORK PROGRAMME OF THE EUROPEAN COMMUNITY FOR RESEARCH, TECHNOLOGICAL DEVELOPMENT AND DEMONSTRATION ACTIVITIES PRIORITY 5: Food Quality and Safety 5.4.8 Area: Environmental health risks 5.4.8.1 (T44) Effects of environmental exposure to complex chemical mixtures SPECIFIC TARGETED RESEARCH PROJECT (STREP) High and low risk of gastrointestinal cancer incidence and chemical exposure related to dietary behaviour Acronym ?EUROHEALTHYFOOD? PROPOSING AGENCY Polo Oncologico ?Regina Elena?, Roma PARTNERS Istituto Zooprofilattico delle Regioni Lazio e Toscana Università degli Studi di Roma ?Tor Vergata? Regione Lazio ? Agenzia di Sanità Pubblica Regione Lazio Assessorato alla Sanità ? Servizi Veterinari Regione Toscana ...

Urology Urological Emergencies in Clinical Practice Hashim , Hashim, Reynard , John, Cowan , Nigel C. 2004, Approx. 185 p. 61 illus., 5 in color., Softcover ISBN: 1-85233-811-3 Männersprechstunde - das Praxishandbuch zu Beratung, Prävention und Therapie Böhm , Michael; Jockenhövel , Friedrich; Weidner , Wolfgang (Eds.) 2004, 418 p. 100 illus. 15 in color, Hardcover ISBN: 3-540-00915-9 English translation Medical Consultation for Men - The Handbook for Advice, Prevention and Therapy Men are the focus in this book - Männersprechstunde has been written for all doctors involved in health care of men. Whether urologist, internist or general practitioner - substantiated information on prevention and therapy of diseases affecting the elderly man plus practical tips from experienced clinicians ...

I Gastrointestinal (GI) malignancies account for a large percentage of the cancer burden in the United States. Although the majority of cancer cases are sporadic, approximately 5% to 10% of cancer results from inherited genetic mutations. There are several hereditary cancer syndromes of the GI tract that have been identified. To date, the genetics of colorectal cancer and its associated hereditary cancer syndromes have been characterized in detail, and effective screening modalities and recommendations have been incorporated into standards of care. Today, scientists are beginning to understand the genetic basis of pancreatic and gastric cancer , and in some cases have identified a number of their associated inherited cancer syndromes. Information about cancer genetics and hereditary cancer syndromes not only will provide advanced practice ...

ANNUAL RESEARCH REPORT 1998 143 Gastrointestinal Cancer Unit Gastrointestinal Cancer Unit, RMT Sutton (in association with the ICR Section of Medicine) HOSPITAL-BASED CLINICAL RESEARCH Head of Unit D Cunningham MD FRCP T he GI Unit is one of the largest clinical units in the Trust seeing between 900 and 1000 new patients a year with gastro- intestinal malignancies. The Unit enters over 70% of patients into prospective clinical trials, many of which are multicentred UK trials coordinated by the MRC or UKCCCR. New drug development, in collaboration with the CRC Centre for Cancer Therapeutics, and metabolic imaging are also major components of the Unit’s work. We have coordinated the RASCAL group which has shown that the presence of mutations in K-ras conveys an increased risk of relapse following potentially ...

Pilot Projects Program Grant Application Gastrointestinal Cancer Pilot Project Grant Application Instructions Deadline: November 21, 2005 Page 2 Pilot Projects Program Grant Application Abramson Cancer Center of the University of Pennsylvania and the University of Pennsylvania’s NIH Center for Molecular Studies in Gastrointestinal and Liver Diseases Deadline: November 21, 2005 Submission & Budget Guidelines The Abramson Cancer Center of the University of Pennsylvania and the UPenn NIH Center for Gastrointestinal and Liver Diseases announces the availability of Pilot Project Grants for faculty to conduct cancer -related research projects. Investigator Eligibility • Full-time University faculty who have not held extramural support (R29, RO1, PO1) are eligible to apply for the Gastrointestinal Cancer Pilot ...