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• BRIEF REPORTS • Raman spectra of single cell from gastrointestinal cancer patients Xun-Ling Yan, Rui-Xin Dong, Lei Zhang, Xue-Jun Zhang, Zong-Wang Zhang ELSEVIER PO Box 2345, Beijing 100023, China World J Gastroenterol 2005;11(21):3290-3292 www.wjgnet.com World Journal of Gastroenterology ISSN 1007-9327 wjg@wjgnet.com © 2005 The WJG Press and Elsevier Inc. All rights reserved. Xun-Ling Yan, Rui-Xin Dong, School of Physics Science and Information Engineering, Liaocheng University, Liaocheng 252059, Shandong Province, China Lei Zhang, Xue-Jun Zhang, Zong-Wang Zhang,Surgery of Liaocheng People’s Hospital, Liaocheng 250059, Shandong Province, China Supported by the National Natural Science Foundation of China, No. 60471049 and the Natural Science Foundation of Shandong Province of China, No. Y2004G09 Correspondence to: Xun-Ling Yan, School ...

The Epidermal Growth Factor Receptor As a Target for Gastrointestinal Cancer Therapy Karen L. Tedesco, MD A. Craig Lockhart, MD Jordan D. Berlin, MD * Address * Vanderbilt University Medical Center, 777 Preston Research Building, Nashville, TN 37232, USA. E-mail: jordan.berlin@vanderbilt.edu Current Treatment Options in Oncology 2004, 5: 393 –403 Current Science Inc. ISSN 1527-2729 Copyright © 2004 by Current Science Inc. Opinion statement The epidermal growth factor receptor (EGFR) is a member of the family of transmem- brane protein kinase receptors known as the erbB or HER receptor family. When acti- vated, EGFR phosphorylates and activates other intracellular proteins that affect cell signaling pathways, cellular proliferation, control of apoptosis and angiogenesis. EGFR signaling is best thought of as a network ...

gastrointestinal cancer 1581 Oral Neoplasia Reference: Chapter 18 Cancer of the Gastrointestinal Tract, A. Cancer of the Oral Cavity, in: Small Animal Clinical Oncology, 3rd ed., Withrow SJ, MacEwen EG. pp. 305 - 318 Click to add sub-title General Information Oral Neoplasia 6% of all canine cancers; 4th most common only 3% of all feline cancers Malignant vs Benign histologic differences are often confusing e.g. fibrosarcoma and fibroma are often histologically similar in appearance if a lesion is rapidly growing, or recurrent (after removal), or invading bone, or pigmented, or ulcerated, then treat lesion as if malignant! Five Most Common Oral Tumors in the Dog Squamous Cell Carcinoma (SCC) Malignant Melanoma (MM) Fibrosarcoma (FSC) Osteosarcoma ...

Abstract: Significant benefits have been gained with pre or peri-operative nutritional support in surgical patients with malnutrition. Recent studies have also shown that some enteral formulas including certain nutrients like glutamine could provide more benefit than the standard formulas. In this prospective-randomized study, the effects of perioperative oral supplement with enteral formulas containing glutamine in comparison with a standard enteral formula in patients who were operated on for GI malignancies were examined. Thirty-two patients were divided into two groups: the study group was given oral supplement with an elemental diet (Alitraq ® ) for 7 days preoperatively and 10 days postoperatively as 30-35% of total daily requirement (standard hospital diet: 65- 70%), while the control group received a polymeric formula (Ensure ® ) as the ...

Received: 10 December 1998 Accepted: 25 May 1999 Abstract Background: Principles of the treatment of gastrointestinal cancer with gene therapy evolved from the advent of techniques in mo- lecular biology, from increasing in- sights into the molecular basis of tu- morigenesis and from the need to de- velop more efficient treatment mo- dalities. Any gene therapy approach has to take two major tasks into con- sideration: the therapeutic gene has to be delivered into the target cell population with high efficiency, specificity and safety, and has to act in a way that provides a benefit to the patient. Discussion: Data on 22 clinical trials on malignancies of the gastrointestinal tract are available. They utilize a variety of gene-deliv- ery methods and target cell popula- tions, and there is considerable vari- ety among their strategies. Gene transfer ...

FRIDAY Joint Symposium: MOGA / ANTIGER Neuroendocrine Tumours – Recent Advances in DIAGNOSIS AND Management 18 Neuroendocrine GEP-tumors: Advances in Diagnosis and Treatment By Kjell Öberg, M.D., Ph.D. Professor Endocrine Oncology Dept. of Endocrine Oncology, Uppsala University Hospital, Uppsala, Sweden Neuroendocrine tumors of the gastrointestinal tract and pancreas constitute about 2 % of all malignant tumors. They include a number of different tumors, derived from cells of the diffuse neuroendocrine cell-system. The largest group of neuroendocrine tumors are the so called carcinoids with an incidence of about 2.5/100 000 per year. The old classification of neuroendocrine GEP-tumors is based on the embryonic origin, but there is a new WHO- classification taking into the consideration the tumor biology of different subtypes of neuroendocrine tumors. The tumors exhibit substantial differences in ...

Version 1.0 08/12/1999 June 20, 2003 EORTC Data Center Av. E. Mounier 83/11 1200 Brussels, Belgium Direct phone: + 32 2 774 16 11 Fax: + 32 2 772 35 45 EORTC GASTROINTESTINAL TRACT CANCER AND RADIOTHERAPY GROUP INTEREST FORM Randomised phase II/III study comparing Gemcitabine followed by Gemcitabine plus concomitant radiation (50.4 Gy) versus control after curative pancreaticoduodenectomy for pancreatic head cancer “40013/22012” I, the undersigned declare that I have read the proposed study outline and I am interested in entering patients in the study YES NO I understand that this procedure is not binding me/my center to the study but I realize that preliminary interest will be used to evaluate the potential accrual of the proposed trial and set up the study infrastructure Expected accrual per YEAR: patients ...

Web Immagini Gruppi Directory News altro » Ricerca avanzata Preferenze Cerca nel Web Cerca solo le pagine in Inglese Spiacenti, nessun contenuto associato a questo URL Web La ricerca di - cache:RpHqojNEAaoJ:www.cancervic.org.au/cancer1/professionals/key_published_articles/05-gastrointestinal.pdf allintitle: gastrointestinal cancer filetype:pdf OR filetype:doc OR filetype:ppt OR filetype:xls OR filetype:rtf - non ha prodotto risultati in nessun documento. Suggerimenti: Assicurarsi che tutte le parole siano state digitate correttamente. Provare con parole chiave diverse. Provare con parole chiave più ...

B.C. Cancer Agency Protocol Summary GIFUC Page 1 of 3 BCCA Protocol Summary for Palliative Chemotherapy for Upper Gastrointestinal Tract Cancer (Gastric, Esophageal, Gall Bladder Carcinoma and Cholangiocarcinoma) and Metastatic Anal Cancer using Infusional Fluorouracil and Cisplatin Protocol Code GIFUC Tumour Group Gastrointestinal Contact Physician GI Systemic Therapy ELIGIBILITY : Metastatic or unresectable adenocarcinoma of the upper gastrointestinal tract (stomach, esophagus, gall bladder, bile ducts) Metastatic squamous cell or cloacogenic carcinoma of the anal canal ECOG 0-2 EXCLUSIONS : CNS metastases Uncontrolled high blood pressure, unstable angina, symptomatic congestive heart failure, myocardial infarction within the preceding 6 months, serious uncontrolled cardiac dysrhythmia Inadequate hepatic ...

March 2003, Vol. 32 No. 2 219 Peritoneal Carcinomatosis from GI Cancer —D G Jayne * Senior Lecturer & Honorary Consultant Surgeon Academic Surgical Unit St. James’s University Hospital & University of Leeds, UK (formerly Colorectal Fellow, Singapore General Hospital, Singapore) Address for Reprints: Dr David Jayne, Academic Surgical Unit, Level 8, Clinical Sciences Building, St. James’s University Hospital, Beckett Street, Leeds LS9 7TF, United Kingdom. E-mail: meddgj@leeds.ac.uk The Molecular Biology of Peritoneal Carcinomatosis from Gastrointestinal Cancer D G Jayne,* MBBCh, MD, FRCS Abstract Introduction: Peritoneal carcinomatosis is a frequent form of disease progression in gastrointestinal cancer , and all too often is a preterminal event with a median survival of only 6 months. Despite the introduction of aggressive surgical and ...

TUMOR M2-PK IN THE DIAGNOSIS OF GASTROINTESTINAL CANCER B.K. NGOUMOU, J. RUPP, P.D. HARDT, H. SCHNELL-KRETSCHMER and H.-U. KLOER Third Medical Department, Justus-Liebig-University, Giessen, Germany Introduction: Tumor M2-PK is the dimeric isoform of the tetrameric glycolytic enzyme pyruvate kinase. It is strongly overexpressed in tumor cells due to their modified metabolic state. It can be quantified in EDTA plasma with a commercially available ELISA test kit. Recent reports indicate that Tumor M2-PK is a marker for renal cell carcinoma and lung cancer [1,2]. It has also been investigated in pancreatic cancer and gastric cancer with promising results [3]. This study was designed to evaluate the use of this marker in gastrointestinal cancer . Because elevation of tumor markers sometimes can be observed in inflammatory ...

PRACTICAL GASTROENTEROLOGY • MARCH 2004 52 INTRODUCTION N umerous studies have been done to examine what role diet plays in protection against gastrointesti- nal cancers. In order to make the best suggestions for physicians and patients, a careful review of the data is provided. The area of diet and cancer prevention is evolving, and, at the current time, much of the data is epidemiological or from basic science animal models. Some of the data is from humans in retrospective for- mat, prospective cohorts, and a few randomized placebo controlled studies. In order to understand the evolution and how suggestions are being formed, it is essential to review all of the studies available as each type has value. This article provides a review of the best data available and makes suggestions based on the literature at hand in regards to nutrients, diet, and cancer preven- ...

Summer 2005 Issue 1 Gastrointestinal Cancer Rapid Medical Donation Program Newsletter Inside: Meet The Lab 2 Participant Family Corner 3 Contact Information 4 Related Programs - NFPTR 6 Related Programs - Breast Cancer Medical Donation 6 The Johns Hopkins University School of MedicineKnowledge, For The World I write to you today with two goals-to introduce both myself and my laboratory to you, and to provide an update of the tremendous impact your loved one has made by participating in the Johns Hopkins Gastrointestinal Cancer Rapid Medical Donation Program (GICRMDP). Who am I? Born and raised in Bayshore, New York, I learned at the early age of 10 how devastating a cancer diagnosis can be when my father passed away of advanced colorectal cancer . When he was diagnosed, the cancer had already ...

gastrointestinal cancer Laparoscopic Ultrasound in Upper Gastrointestinal Cancer Staging Jesper Durup,MD,PhD and Claus Hovendal,MD,PhD Dept of Surgical Gastroenterology, Odense University Hospital, Denmark Introduction: Besides having a correct diagnosis accurate pretherapeutic staging and assessment of resectability in upper gastrointestinal malignancies (UGIM) are important in order to group the patients for different treatment strategies. One of the most important clinical tasks is to identify the patients that cannot be operated. Unnecessary laparotomies in patients with non-resectable UGIM will increase mortality and morbidity as well as reduce the quality of life in their short remaining life time period. In this chapter we will discuss the use of Laparoscopic Ultrasound (LUS) regarding the pretherapeutic identification of non-resectable UGIM, and comment ...

Cancer Therapy Vol 3, page 525 525 Cancer Therapy Vol 3, 525-530, 2005 Incidence of gastrointestinal toxicity during estramustine phosphate therapy for prostate cancer is associated with the single-nucleotide polymorphisms in the cytochrome P450 1A1 (CYP1A1) gene Research Article Mohammed Rafiqul Islam Mamun 1 , Motofumi Suzuki 1 , Satoru Takahashi 1 , Kazuo Hara 2 , Takeshi Ozeki 3 , Yasuhiko Yamada 3 , Takashi Kadowaki 4 , Yoshitsugu Yanagihara 5 , Shuji Kameyama 6 , Yoichi Minagawa Ito 7 , Takumi Takeuchi 1 and Tadaichi Kitamura 1, * 1 Department of Urology, Graduate School of Medicine, The University ...

Dog AKC Number __ Please check all applicable boxes Cancer Hemangiosarcoma Affected Littermate Affected Produced affected offspring Lymphoma Affected Littermate Affected Produced affected offspring Mast cell Affected Littermate Affected Produced affected offspring Osteosarcoma Affected Littermate Affected Produced affected offspring Other _ Affected Littermate Affected Produced affected offspring Cardiac disorders Subaortic stenosis Affected Littermate Affected Produced affected offspring Dermatological disorders Atopic dermatitis Affected Littermate Affected Produced affected offspring Gastrointestinal disorders Bloat Affected Littermate Affected Produced affected offspring Megaesophagus Affected ...

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Pilot Projects Program Grant Application Gastrointestinal Cancer Pilot Project Grant Application Instructions Deadline: November 21, 2005 Page 2 Pilot Projects Program Grant Application Abramson Cancer Center of the University of Pennsylvania and the University of Pennsylvania’s NIH Center for Molecular Studies in Gastrointestinal and Liver Diseases Deadline: November 21, 2005 Submission & Budget Guidelines The Abramson Cancer Center of the University of Pennsylvania and the UPenn NIH Center for Gastrointestinal and Liver Diseases announces the availability of Pilot Project Grants for faculty to conduct cancer -related research projects. Investigator Eligibility • Full-time University faculty who have not held extramural support (R29, RO1, PO1) are eligible to apply for the Gastrointestinal ...

Mouse Models for gastrointestinal cancer Raju Kucherlapati Colorectal cancer ( CRC) is one of the most common cancers in the Western hemisphere. In the United States alone, nearly 150,000 new cases of CRC are reported every year and 56,000 deaths are attributed to this cancer. The most frequent form of CRC is sporadic colorectal cancer. Nearly 85% of CRC is sporadic in origin. The second most frequent (5%) cases of colorectal cancer are referred to as hereditary non-polyposis colon cancer ( HNPCC). The least frequent form (1/12000) of colorectal cancer is familial adenomatous polyposis (FAP). Several genes that are involved in the initiation and progression of CRC have been identified. FAP is inherited as an autosomal dominant disorder. Individuals with FAP develop large numbers of adenomas in their colon and rectum during their late teens or early twenties. The adenomas are capable of progressing ...

Urology Urological Emergencies in Clinical Practice Hashim, Hashim, Reynard, John, Cowan, Nigel C. 2004, Approx. 185 p. 61 illus., 5 in color., Softcover ISBN: 1-85233-811-3 Männersprechstunde - das Praxishandbuch zu Beratung, Prävention und Therapie Böhm, Michael; Jockenhövel, Friedrich; Weidner, Wolfgang (Eds.) 2004, 418 p. 100 illus. 15 in color, Hardcover ISBN: 3-540-00915-9 English translation Medical Consultation for Men - The Handbook for Advice, Prevention and Therapy Men are the focus in this book - Männersprechstunde has been written for all doctors involved in health care of men. Whether urologist, internist or general practitioner - substantiated information on prevention and therapy of diseases affecting the elderly man plus practical tips from experienced clinicians help the reader advise and treat ...

Molecular pathogenesis of epigenetic alterations in gastrointestinal cancer and its application to diagnosis and treatment Kohzoh Imai (Sapporo Medical University, President) ?Outline of survey? Epigenetic alterations such as DNA methylation and histone modification play an important role in inactivation of tumor suppressor genes. However, it remains unclear how methylation contributes to tumor formation and progression. In addition, precise mechanisms of methylation dependent gene silencing are not fully understood. This study aims to understand the molecular mechanisms how epigenetic alterations contribute to tumorigenesis of gastrointestinal cancers. We also try to apply epigenetic alterations to develop novel methods for diagnosis and therapy. To this end, we try to understand molecular mechanisms how DNA methyltransferase inhibitors suppress cancer cells by screening pro-apoptotic ...

The Twelfth International Conference on Gastrointestinal Cancer : Announcement and Call for Abstracts Pancreas, Biliary Tract, Hepatoma, and Hepatic Metastasis The Twelfth International Conference on Gastrointestinal Cancer : Announcement and Call for Abstracts Pancreas, Biliary Tract, Hepatoma, and Hepatic Metastasis October 20-22, 2005 University of Virginia – Charlottesville,Virginia October 20-22, 2005 University of Virginia – Charlottesville,Virginia Presented by: The University of Virginia Health System • The George Washington University Medical Center Université Victor Ségalen • Institut Bergonié Sponsored by: The Office of Continuing Medical Education,University of Virginia School of Medicine Page 2 Who Should Attend? This international conference ...