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A204: Liver cancer tissues - Hepatocellular carcinoma For research use only (formalin fixed) Specifications: •No. of cases: 35 •Tissue type: Liver cancer tissues – Hepatocellular carcinoma •No. of spots: 2 spots from each cancer case (70 spots) 4 non-neoplastic spots (4 spots) •Total spots: 74 •Corresponding normal tissues with cancers: Yes •Diameter: 1.0 mm Documents: •Product specification: layout, summary of tissue spots •H&E stained images •Detailed pathological information Layout: Page 2 A204 : Liver cancer tissues - Hepatocellular carcinoma For research use only (formalin fixed) Summary of tissue spots No. Sex Age KeyWord E-S grade* TNM Stage 1 1, 2 f 48 hepatocellular carcinoma I T2NxM0 (II) ...

A205 : Liver cancer tissues - Cholangiocarcinoma For research use only (formalin fixed) Specifications: •No. of cases: 46 •Tissue type: Liver cancer tissues – Chalangicarcinoma •No. of spots: 2 spots from each cancer case (92 spots) 4 non-neoplastic spots (4 spots) •Total spots: 96 •Corresponding normal tissues with cancers: No •Diameter: 1.0 mm Documents: •Product specification: layout, summary of tissue spots •H&E stained images •Detailed pathological information Layout: Page 2 A205 : Liver cancer tissues - Cholangiocarcinoma For research use only (formalin fixed) Summary of tissue spot No Sex Age KeyWord Grade TNM Stage 1 1, 2 f 73 Cholangio ca. G1 T1N0M0 (I) 2 3, 4 f 69 ...

A205 : Liver cancer tissues - Cholangiocarcinoma (formalin fixed) For research use only Specifications: •No. of cases: 46 •Tissue type: Liver cancer tissues – Chalangicarcinoma •No. of spots: 2 spots from each cancer case (92 spots) 4 non-neoplastic spots (4 spots) •Total spots: 96 •Corresponding normal tissues with cancers: No •Diameter: 1.0 mm Documents: •Product specification: layout, summary of tissue spots •H&E stained images •Detailed pathological information Layout: Page 2 Summary of tissue spot A205 : Liver cancer tissues - Cholangiocarcinoma (formalin fixed) For research use only No Sex Age KeyWord Grade TNM Stage 1 1, 2 f 73 Cholangio ca. G1 T1N0M0 (I) 2 3, 4 f 69 ...

Published by Oxford University Press on behalf of the International Epidemiological Association International Journal of Epidemiology 2005; 34: 403–404 © The Author 2005; all rights reserved. Advance Access publication 19 January 2005 doi:10.1093/ije/dyi004 Commentary: Liver cancer and the epidemiological and cancer transition theories Omer Gersten The article by Shibuya and Yano 1 in this issue investigates the most common form of liver cancer in Japan, hepatocellular carcinoma (HCC). Using log-linear Poisson regression models and addressing the problem of non-identifiability, the authors attempt to tease out the influence of age, period, and cohort effects on HCC mortality. An important conclusion of the article is that HCC death rates are highest in cohorts born around 1930. Another conclusion at the opposite end of the spectrum also deserves to be stressed. ...

• BRIEF REPORTS • Expression of cyclooxygenase-2 in gastric cancer and its relation to liver metastasis and long-term prognosis Ji-Ren Yu, Yi-Jun Wu, Qi Qin, Ke-Zheng Lu, Sheng Yan, Xiao-Sun Liu, Shu-Sen Zheng ELSEVIER PO Box 2345, Beijing 100023, China World J Gastroenterol 2005;11(31):4908-4911 www.wjgnet.com World Journal of Gastroenterology ISSN 1007-9327 wjg@wjgnet.com © 2005 The WJG Press and Elsevier Inc. All rights reserved. Ji-Ren Yu, Yi-Jun Wu, Ke-Zheng Lu, Sheng Yan, Xiao-Sun Liu, Shu-Sen Zheng, Department of Gastrointestinal Surgery, First Affiliated Hospital, Medical School, Zhejiang University, Hangzhou 310003, Zhejiang Province, China Qi Qin, Department of General Surgery, Children Hospital, Medical School, Zhejiang University, Hangzhou 310003, Zhejiang Province, China Supported by the Natural Science Foundation of Zhejiang ...

Iran Daily July 25, 2005 4 FARMANIEH You have to see to believe it! 240 sq.m., 3 bdrms, 3 svcs, 3 balconies, f. furn., panoramic view, s/p, sauna, jacuzzi $ 2,000 NAJM SHAHRAK-E GHARB Apt./Villa 180 sq.m., 3 bdrms, s/p, quiet area Only $ 1,400 PAYAM ELAHIEH $ 3,000 385 sq.m., 4 bdrms, 5 svcs, 3 master bdrms, big balconies, elegantly furn., fantastic view, s/p, sauna, jacuzzi NAJM PASDARAN 105 sq.m., 2 bdrms, nice furniture, parking space, tel. lines $ 750 or Best Offer PAYAM JORDAN 200 sq.m., 3 bdrms, f. furn. $ 2,600 150 sq.m., 3 bdrms, f. furn. $ 1,700 140 sq.m., 3 bdrms, f. furn. $ 1,400 s/p, sauna, jacuzzi, with each flat SAM ...

World Chin J Digestol 2005 July 15;13(13):1507-1509 ÊÀ½ç»ªÈËÏû»¯ÔÓÖ¾ ISSN 1009-3079 CN 14-1260/R PO Box 2345 Beijing 100023, China Fax: +86-10-85381893 Email: wcjd@wjgnet.com www.wjgnet.com • LIVER CANCER • Effects of inflammatory cytokines on metastasis of liver cancer after apparently curative operation Li Bai, Gao-Ping Mao, Chuan-Ping Cao, Ying-Hui Zhang Li Bai, Gao-Ping Mao, Chuan-Ping Cao, Ying-Hui Zhang, Department of Digestive Diseases, General Air Force Hospital, Beijing 100036, China Correspondence to: Dr. Li Bai, Department of Digestive Diseases, General Air Force Hospital, 30 Fucheng Road, Beijing 100036, China. bai_li@hotmail.com Received: 2005-04-15 Accepted: 2005-05-14 Abstract AIM: To explore the effects of relevant inflammatory cytokines on the metastasis of liver cancer after appar- ently curative operation. ...

NEWS RELEASE Page 1 of 2 THYMITAQ ® COMPLETES ENROLLMENT IN PIVOTAL PHASE III LIVER CANCER STUDY THYMITAQ ® (nolatrexed dihydrochloride) may offer treatment option for patients with inoperable primary liver cancer Berwyn, PA / April 19, 2005 / PR Newswire / -- Eximias Pharmaceutical Corporation (Eximias) announced today that it has completed enrollment in its pivotal Phase III clinical study with THYMITAQ ® in patients with inoperable primary liver cancer (hepatoma, hepatocellular carcinoma or HCC). The Phase III study, coined the ETHECC © trial (Evaluation of THYMITAQ ® in Unresectable Hepatocellular Carcinoma), is comparing survival in a randomized trial of patients with inoperable primary liver cancer treated with THYMITAQ ® , an investigational ...

• CASE REPORT • Metastatic liver cancer : A rare case Bong-Wan Kim, Hee-Jung Wang, In-Ho Jeong, Sang-Ick Ahn, Myoung-Wook Kim ELSEVIER PO Box 2345, Beijing 100023, China World J Gastroenterol 2005;11(27):4281-4284 www.wjgnet.com World Journal of Gastroenterology ISSN 1007-9327 wjg@wjgnet.com © 2005 The WJG Press and Elsevier Inc. All rights reserved. Bong-Wan Kim, Hee-Jung Wang, In-Ho Jeong, Sang-Ick Ahn, Myoung-Wook Kim, Department of Surgery, Ajou University School of Medicine, Suwon, South Korea Correspondence to: Hee-Jung Wang, MD, PhD, Department of Surgery, Ajou University School of Medicine, San-5 Youngtong ku, Wonchon dong, Suwon 442-749, South Korea. wanghj@ajou.ac.kr Telephone: +82-31-219-5011 Fax: +82-31-219-5755 Received: 2004-11-29 Accepted: 2005-01-05 Abstract Hemangiopericytoma is a rare tumor especially when ...

LIVER CANCER Cancer Contr ol Cancer Control Bulletin Issue 30 • January/February 2003 Information for GPs LIVER CANCER SOUTH EAST HEALTH Hepatocellular carcinoma (HCC) and colorectal liver metastases are the most common types of tumours in the liver treated in South Eastern Sydney. Hepatocellular carcinoma In Australia, HCC is a relatively rare cancer , accounting for 1.4% of cancer deaths. Males are 3 times more likely to be diagnosed with primary liver cancer as females and 3.6 times as likely to die from the disease. The incidence of HCC has trebled in the last 20 years, mainly due to the spread of hepatitis B and C virus (HBV and HCV). Five-year survival has improved only marginally in that time and is currently 8% for males and 11% for females. HCC is endemic in developing countries, where three-quarters of the world’s cases ...

Center for Environmental Health Studies (617) 482-9485 44 Farnsworth Street, Boston, MA 02210 http://www.jsi.com Liver Cancer and Exposure to Ionizing Radiation 1 Liver Cancer and (including intra-hepatic bile duct) Exposure to Ionizing Radiation Summary: Moderately strong evidence has been recorded of a possible connection between liver cancer deaths and exposure to ionizing radiation. This evidence is based upon studies conducted at Los Alamos National Laboratory, studies of nuclear workers at other sites, and others exposed to ionizing radiation. These findings are consistent with the National Research Council’s determination that the liver is sensitive to ionizing radiation. Liver cancer is designated as a “specified” cancer under the Energy Employees Occupational Illness Compensation Program Act. Historically, incidence of liver cancer has ...

Last revised: 4/21/05 UM Cancer Center Patient Education Document #0032 Apr05 Ed. Online version: http://www. cancer .med.umich.edu/learn/percpathways.htm University of Michigan Comprehensive Cancer Center Patient Education Resource Center (PERC) INFORMATION GUIDE Liver Cancer The purpose of this information guide is to help patients newly diagnosed with Liver Cancer and their families to find sources of information and support. This list is not meant to be comprehensive, but rather to provide starting points for information seeking. The materials can be found at the Patient Education Resource Center at the University of Michigan Comprehensive Cancer Center in room B1-361. Brochure Available free at the Patient Education Resource Center on Level B-1 National Cancer Institute. What You Need To Know About: Liver Cancer ...

Last Revised: 3/18/2005 UM Comprehensive Cancer Center Patient Education Document # 0015 Mar05 Ed. Online version: http://www. cancer .med.umich.edu/learn/percpathways.htm University of Michigan Comprehensive Cancer Center Patient Education Resource Center (PERC) INFORMATION GUIDE Childhood Cancer : Liver Cancers The purpose of this information guide is to help parents of children newly diagnosed with liver tumors find sources of information and support. This list is not meant to be comprehensive, but rather to provide starting points for information seeking. The materials can be found at the Patient Education Resource Center at the University of Michigan Comprehensive Cancer Center in room B1-361. Book Chapters Available for loan in the Patient Education Resource Center on level B1 room 361 Janes-Hodder, Honna & Keene, ...

research for a cure laboratory without walls National Foundation for Cancer Research Cancer FAQs about liver cancer Frequently Asked Questions about common cancers. Page 2 Cancer FAQs What are the different types of liver cancer ? There are many kinds of tumors than can originate in the liver . Of the four main types that are cancerous (angiosarcomas, cholangiocarcinomas, hepatoblastomas, and hepatocellular carcinomas), hepatocellular carcinoma (also called hepatoma or HCC), is by far the most common, accounting for about 84 percent of all liver cancer cases. HCC starts growing in the hepatocytes, the main type of cell found in the liver . What are the risk factors for liver cancer ? A risk factor is anything that increases a person’s chance of getting a disease. There are several known risk factors ...

• LIVER CANCER • Hepatic artery infusion of antisense oligodeoxynucleotide and lipiodol mixture transfect liver cancer in rats Han-Ping Wu, Gan-Sheng Feng, Yuan Tian ELSEVIER PO Box 2345, Beijing 100023, China World J Gastroenterol 2005;11(16):2408-2412 www.wjgnet.com World Journal of Gastroenterology ISSN 1007-9327 wjg@wjgnet.com © 2005 The WJG Press and Elsevier Inc. All rights reserved. Han-Ping Wu, Gan-Sheng Feng, Department of Interventional Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China Yuan Tian, Laboratory of General Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China Correspondence to: Dr. Han-Ping Wu, Department of Interventional Radiology, Union Hospital, ...

1672 Main St. Ste. E #264 • Ramona, CA 92065 • Tel: 760.789.8928 • Fax: 760.789.8929 • Toll Free: 800.475.1955 • www.proteinbiotechnologies.com HUMAN LIVER CANCER TISSUE MICROARRAY Catalog Number: TMA-018 Each core from each tissue represents one specimen selected and pathologically confirmed. Normal matched or unmatched liver tissue is provided for comparison to the cancer tissue. Cases : 75 Cores : 80 Diameter : 1.5 mm Thickness: 5 µm Standard IHC: Cytokeratin confirmed Layout : 8 x 10 1 2 3 4 5 6 7 8 9 10 A 1 2 3 4 5 6 7 8 9 10 B 11 12 13 14 15 16 17 18 19 20 C 21 22 23 24 25 26 27 28 29 30 ...

N N E E W W S S 4 February 2004 Revolutionary liver cancer treatment to be showcased at Medway The Medway NHS Trust is hosting a ground breaking clinical workshop on 17 February 2004 at the Medway Maritime Hospital, Gillingham which will include two live demonstrations of an exciting new procedure for the diagnosis and treatment of liver cancer . The internationally respected specialist, Professor R Lencioni of Pisa Hospital, Italy, will perform this procedure, which is based on Contrast Enhanced Ultrasound (CEUS) and Radiofrequency Ablation (RFA). The thrust of this new advance is local deposition of thermal energy directly to the tumour cells, which heats and destroys the cancerous tissue. Electrodes shaped like needles are inserted into the liver . This is achieved without making cuts and Ultrasound images allow the ...

LIVER RESECTION FOR TREATMENT OF CANCER MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA Broadcast February 3, 2005 NARRATOR Welcome to a live webcast from Massachusetts General Hospital in Boston. During this live webcast, surgeons will demonstrate a liver resection to treat cancer . Today’s program is part of Massachusetts General Hospital’s ongoing educational efforts to bring the latest information in health care to patients and physicians. During this program, you may send your questions to the OR surgeons at any time. Just click the MDirectAccess button on the screen. SAM YOON, M.D. Good afternoon and welcome to Massachusetts General Hospital. I’m Dr. Sam Yoon. I’m one of the surgical oncologists at the Mass. General Hospital. I’m sitting outside OR 43. Today we’re going to show you portions of a right liver resection or right hepatectomy. The patient today is a 69-year-old woman who actually ...

!"# !$%&'%(!)* #+%,!-./)01%2!34).3#+%5$6.1/ '%7! 6.3!1 Waikato District Health Board Hepatitis and liver cancer Hospitalisations (0-74) Introduction Rationale Methodology Data Coverage Period The period of this data is from 1997 to 2003. Tables that have no years presented in their axes, use data from the entire period span. Method Description Interpretation International Classification of Disease Codes (ICD Version 9 & 10) ICD 9 ICD 10 Findings 1 Ethnicity Volume Trend 2 Age Gender Volume Proportion Profile 3 Age Ethnicity Volume Profile - All years 4 Age Ethnicity Volume Proportion Profile - All years 5 Age Standardised Trend - Waikato District Health Board versus NZ rate per 10,000 persons 6 Maori Age Standardised Trend - Waikato District Health Board versus NZ rate per 10,000 persons 7 Paciifc People ...

!"# !$%&'%(!)* #+%,!-./)01%2!34).3#+%5$6.1/ '%7! 6.3!1 Waikato District Health Board Hepatitis and liver cancer Mortality (0-74) Introduction Rationale Methodology Data Coverage Period Method Description Interpretation International Classification of Disease Codes (ICD Version 9 & 10) ICD 9 ICD 10 Findings 1 Ethnicity Volume Trend 2 Age Gender Volume Proportion Profile 3 Age Ethnicity Volume Profile - All years 4 Age Ethnicity Volume Proportion Profile (All Years) 5 Age Standardised Trend - Waikato District Health Board versus NZ rate per 10,000 persons 6 Maori Age Standardised Trend - Waikato District Health Board versus NZ rate per 10,000 persons 7 Paciifc People Age Standardised Trend - Waikato District Health Board versus NZ rate per 10,000 persons 8 Other Ethnicity Age Standardised Trend - Waikato District ...

!"# !$%&'%(!)* #+%,!-./)01%2!34).3#+%5$6.1/ '%7! 6.3!1 Waikato District Health Board Hepatitis and liver cancer Hospitalisations Introduction Rationale Methodology Data Coverage Period The period of this data is from 1997 to 2003. Tables that have no years presented in their axes, use data from the entire period span. Method Description Interpretation International Classification of Disease Codes (ICD Version 9 & 10) ICD 9 ICD 10 Findings 1 Ethnicity Volume Trend 2 Age Gender Volume Proportion Profile 3 Age Ethnicity Volume Profile - All years 4 Age Ethnicity Volume Proportion Profile - All years 5 Age Standardised Trend - Waikato District Health Board versus NZ rate per 10,000 persons 6 Maori Age Standardised Trend - Waikato District Health Board versus NZ rate per 10,000 persons 7 Paciifc People Age Standardised ...

!"# !$%&'%(!)* #+%,!-./)01%2!34).3#+%5$6.1/ '%7! 6.3!1 Waikato District Health Board Hepatitis and liver cancer Mortality Introduction Rationale Methodology Data Coverage Period Method Description Interpretation International Classification of Disease Codes (ICD Version 9 & 10) ICD 9 ICD 10 Findings 1 Ethnicity Volume Trend 2 Age Gender Volume Proportion Profile 3 Age Ethnicity Volume Profile - All years 4 Age Ethnicity Volume Proportion Profile (All Years) 5 Age Standardised Trend - Waikato District Health Board versus NZ rate per 10,000 persons 6 Maori Age Standardised Trend - Waikato District Health Board versus NZ rate per 10,000 persons 7 Paciifc People Age Standardised Trend - Waikato District Health Board versus NZ rate per 10,000 persons 8 Other Ethnicity Age Standardised Trend - Waikato District Health ...

• LIVER CANCER • Are polymorphisms of N-acetyltransferase genes susceptible to primary liver cancer in Luoyang, China? Xiu-Feng Zhang, Jian-ChaoBian, Xiao-Yan Zhang, Zhu-Mei Zhang, FengJiang, Qi-MinWang, Qi-Jun Wang, Yan-YanCao, Bo-MingTang ELSEVIER PO Box 2345, Beijing 100023, China World J Gastroenterol 2005;11(10):1457-1462 www.wjgnet.com World Journal of Gastroenterology ISSN 1007-9327 wjg@wjgnet.com © 2005 The WJG Press and Elsevier Inc. All rights reserved. Xiu-Feng Zhang, Jian-Chao Bian, Xiao-Yan Zhang, Zhu-Mei Zhang, Feng Jiang, Yan-Yan Cao, Department of Epidemiology, School of Public Health, Fudan University, Shanghai 200032, China Qi-Min Wang, Qi-Jun Wang, Bo-Ming Tang, Department of Epidemiology, Luoyang Center for Disease Control and Prevention, Luoyang 471000, Henan Province, China Supported by the National Natural ...

Tel 800.880.1300 Volume 98 5 Number 10 51 Are deaths from liver cancer , kidney cancer , and leukemia clustered in San Antonio? F. BENJAMIN ZHAN, PHD INTRODUCTION Concerns have arisen that cancer mor- tality rates in San Antonio may be ele- vated (1,2). For example, Bradshaw (2) reported high mortality rates of liver cancer , lung cancer , kidney can- cer, and leukemia per square mile in some areas of San Antonio. However, without consideration of the underly- ing at-risk population and its associ- ated demographic characteristics, mortality rates per square mile alone may give a misleading picture of cancer mortality rates in San Antonio. In addi- tion, to avoid preselection bias, cancer mortality in the entire state of Texas should be analyzed first to determine whether cancer mortality rates are in- deed excessively higher ...

2585 Meadowpine Blvd., Mississauga, Ont., L5N 8H9 www.hemosol.com Tel: 905-286-6200 * FAX: 905-286-6300 Product: HRC 204 Category: Targeted Drug Delivery Indication: Primary Liver Cancer Rationale Hemosol has developed a new and innovative drug delivery system designed to improve the targeted delivery of therapeutic drugs to the liver . This technology utilises a naturally occurring receptor present on liver cells that specifically binds hemoglobin as a means of selectively targeting drugs to the liver . This receptor normally functions to recognise and transport cell-free hemoglobin into the liver once bound to its natural plasma carrier, haptoglobin. The attachment of therapeutic drugs or diagnostic agents to hemoglobin enables selective delivery and uptake across the liver cell membrane as an improved method of targeted drug delivery. The versatility of ...

pg . 21 AD V ANCES in orthomolecular r esear ch Hepatocellular carcinoma ( HCC , also known as primary liver cancer or hepatoma ) is the most common primary, malignant liver tumor, and the fifth most common cancer in the world, with about 430 000 people suffering from it worldwide in 1990. It's as deadly as it is common: almost everyone who develops HCC will die within a year. The single largest risk factor for HCC is viral hepatitis. In fact, if you have chronic hepatitis B infection, your risk of HCC climbs two hundred fold over the rest of the population. (Other risk factors include Hep C , aflatoxin (a toxin produced by some molds in food), some drugs and industrial chemicals (such as vinyl chloride), alcohol abuse , non-viral hepatitis , and the iron-metabolism disorder hemochromatosis ). With the prognosis for HCC so ...

14. Donor and Recipient Tumor Data OPTN/SRTR 2005 Annual Report __ 14-10 Table 14.7 History of Cancer among Deceased Liver Donors 1995 to 2004 „ƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒ† ‚ ‚ Year of Transplant ‚ ‚ ‡ƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒ‰ ‚ ‚ 1995 ‚ 1996 ‚ 1997 ‚ 1998 ‚ 1999 ‚ 2000 ‚ 2001 ‚ 2002 ‚ 2003 ‚ 2004 ‚ ‡ƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒˆƒƒƒƒƒƒƒˆƒƒƒƒƒƒƒˆƒƒƒƒƒƒƒˆƒƒƒƒƒƒƒˆƒƒƒƒƒƒƒˆƒƒƒƒƒƒƒˆƒƒƒƒƒƒƒˆƒƒƒƒƒƒƒˆƒƒƒƒƒƒƒˆƒƒƒƒƒƒƒ‰ ‚ Total Transplants ‚ 60‚ 61‚ 82‚ 86‚ 89‚ 96‚ 96‚ 98‚ 133‚ 141‚ ‡ƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒˆƒƒƒƒƒƒƒˆƒƒƒƒƒƒƒˆƒƒƒƒƒƒƒˆƒƒƒƒƒƒƒˆƒƒƒƒƒƒƒˆƒƒƒƒƒƒƒˆƒƒƒƒƒƒƒˆƒƒƒƒƒƒƒˆƒƒƒƒƒƒƒˆƒƒƒƒƒƒƒ‰ ‚ Type of Cancer ‚ ‚ ‚ ‚ ‚ ‚ ‚ ...

Merseyside and Cheshire Cancer Network Liver Cancer Surgery Surgery for liver cancer is safe and effective: • Operative mortality 1-2% • Median hospital stay 7 days • Median operative blood transfusion: 1 unit • 5 year survival after resection of colorectal cancer liver secondaries is 40% • 10 year survival after resection of colorectal cancer liver secondaries is 25% • Surgery for colorectal cancer liver secondary tumours now accounts for >80% of the activity of the Aintree liver surgery What are the recent developments that are impacting on liver cancer surgery activity? • Historically, <10% of patients with colorectal cancer liver secondaries were thought to be suitable for liver surgery (1,000 patients per year in England) • The recently accepted re-definition of resectability now means that 20% of these patients can now be resected safely with ...

PO Box 2345, Beijing 100023, China World J Gastroenterol 2001;7(6):821-825 Fax: +86-10-85381893 World Journal of Gastroenterology E-mail: wjg@wjgnet.com www.wjgnet.com Copyright © 2001 by The WJG Press ISSN 1007-9327 • ORIGINAL RESEARCH • Expression of liver cancer associated gene HCCA3 Zheng-Xu Wang 1 , Gui-Fang Hu 1 , Hong-Yang Wang 2 , Meng-Chao Wu 2 1 Department of General Surgery, Chinese PLA General Hospital of Lanzhou Military Command, Lanzhou 730050, Gansu Province, China 2 Eastern Hepatobilliary Surgical Hospital, Second Military Medical University, Shanghai 200438, China Supported by the National Natural Science Foundation of China No. 30000077, and Science Funds for Post-doctoral Studies (1999[10]), and Medicial and Health Project Funds of Chinese PLA Lanzhou Command ...

PROFILE JANUARY 2005 22 SCHOLARLY ACTIVITIES SCHOLARLY ACTIVITIES New drug against liver cancer L iver cancer , also known as Hepatocellular Carcinoma or HCC is one of the five most common human cancers in the world and the second leading cause of cancer death in Hong Kong. A joint research team formed among our Department of Applied Biology and Chemical Technology, HKU’s Centre for the Study of Liver Disease and a commercial partner, has broken new ground in developing a drug to fight against liver cancer . The new drug is developed based on the mechanism of arginine depletion which is believed to be effective in inhibiting tumor growth in HCC without affecting the normal cells. Earlier, PolyU researchers have successfully produced a human recombinant arginase that has a prolonged half-life in the circulation to allow therapeutic ...