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Issue Jan2004 Oncology Dept Royal Free Hospital Useful Telephone numbers Listed below are telephone contacts you may wish to use to obtain more information or support Surgical outpatients 0207 830 2826 Oncology outpatients 0207 830 2084 Jex blake ward 0207 830 2718 Chemotherapy suite 0207 830 2273 Information service 0207 472 6739 Counsellors 0207 472 6739 National Cancerbacup 0808 8001234 www.cancerbacup.org.uk Macmillan Cancerline 0808 808 2020 www.macmillan.org.uk We have a leaflet with details of local cancer support organisations- please ask for this. Information leaflet Department of Surgery and Department of Oncology Care and Treatment for Primary Liver Cancer ( Hepatucellular Carcinoma) At the Royal Free Hospital ...

Issue 1 Jan04 Oncology dept Royal Free NHS trust Department of Surgery and Department of Oncology Surgery for Cancer of the liver At the Royal Free Hospital Page 2 Page 3 Benefits Support groups for those affected by cancer Oncology Counselling service A patients guide to Chemotherapy A patients guide to Radiotherapy Other information available: Cancerbacup booklets: Understanding cancer of the liver Primary liver cancer (fact sheet) Other booklets on all aspects of coping with cancer . The Cancerbacup booklets are available on loan from the radiotherapy and oncology information service -0207 472 6739 or direct from Cancerbacup -0808 8001234 (free of charge). We have many more booklets and leaflets on all aspects of coping with cancer in the Information ...

• LIVER CANCER • Specific COX-2 inhibitor NS398 induces apoptosis in human liver cancer cell line HepG2 through BCL-2 Dong-Sheng Huang, Ke-Zhen Shen, Jian-Feng Wei, Ting-Bo Liang, Shu-Sen Zheng, Hai-Yang Xie PO Box 2345, Beijing 100023, China World J Gastroenterol 2005;11(2):204-207 Fax: +86-10-85381893 World Journal of Gastroenterology ISSN 1007-9327 E-mail: wjg@wjgnet.com www.wjgnet.com © 2005 The WJG Press and Elsevier Inc. All rights reserved. ELSEVIER Dong-Sheng Huang, Ke-Zhen Shen, Jian-Feng Wei, Ting-Bo Liang, Shu-Sen Zheng, Hai-Yang Xie, Department of Hepatobiliary Pancreatic Surgery, The First Affiliated Hospital, Zhejiang University, College of Medicine, Hangzhou 310003, Zhejiang Province, China Correspondence to: Dr. Hai-Yang Xie, Department of Hepatobiliary Pancreatic Surgery, The First Affiliated Hospital, College of Medicine, ...

• LIVER CANCER • Survivin antisense compound inhibits proliferation and promotes apoptosis in liver cancer cells De-Jian Dai, Cai-De Lu, Ri-Yong Lai, Jun-Ming Guo, Hua Meng, Wei-Sheng Chen, Jun Gu PO Box 2345, Beijing 100023, China World J Gastroenterol 2005;11(2):193-199 Fax: +86-10-85381893 World Journal of Gastroenterology ISSN 1007-9327 E-mail: wjg@wjgnet.com www.wjgnet.com © 2005 The WJG Press and Elsevier Inc. All rights reserved. ELSEVIER De-Jian Dai, Hua Meng, Department of Surgery, Second Affiliated Hospital of Zhejiang University Medical School, Hangzhou 310009, Zhejiang Province, China Cai-De Lu, Department of Surgery, Lihuili Hospital of Ningbo Medical Center, Ningbo University Medical School, Ningbo 315040, Zhejiang Province, China Ri-Yong Lai, Department of Biochemistry and Molecular Biology, Gannan Medical College, ...

To learn more about our Asian Hepatitis B - Liver Cancer program, please contact us at: Philadelphia Headquarters Office : Center for Asian Health Department of Public Health College of Health Professions Temple University 1415 N. Broad Street, Suite 116 Philadelphia, PA 19122 Tel: 215-787-5431 Fax: 215-787-5436 Email: atecar@astro.temple.edu Website: www.temple.edu/cah New York City Office: Center for Asian Health Temple University 401 Broadway, Suite 2306 New York City, NY 10013 Tel: 212-219-8449 Asian Tobacco Education, Cancer Awareness and Research (ATECAR) and its affiliates provide: tobacco and cancer prevention and intervention activities, and training and research opportunities for Asian Americans. For Information on ATECAR, call 215-787-5431 For Information on Cancer , call Cancer ...

Micronuclei and cell survival in human liver cancer cells irradiated by 25MeV/u 40 Ar 14+ * LI Wen-Jian 1 , GAO Qing-Xiang 2 , ZHOU Guang-Ming 1 and WEI Zeng-Quan 1 1 Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, Gansu Province, China 2 Department of Biology, Lanzhou University, Lanzhou 730000, Gansu Province, China LI Wen-Jian, male, born on 1959-02-22 in Hebei Province, Associate Professor and Deputy Director of the Second Division of Heavy Ion Application. Graduated and obtained a bachelor degree from Hebei University of Technology in 1982, and a master degree from Institute of Modern Physics, Chinese Academy of Sciences in 1992, specialized in the basic study of radiation biological effects and cancer therapy with heavy ions; having 33 papers published. ...

Study on environmental etiology of high incidence areas of liver cancer in China Nian Feng Lin 1 , Jie Tang 1 and Hoteyi S. Mohamed Ismael 2 Subject headings liver neoplasms; etiology; epidemiology; water pollution; environmental carcinogens; nitrosamines; china; geology Lin NF, Tang J, Mohamed Ismael HS.Study on environmental etiology of high incidence areas of liver cancer in China. World J Gastroentero , 2000;6(4):572-576 INTRODUCTION China is a country with a high incidence of liver cancer in some areas [1] . Liver cancer has a wide distribution and threatens human health seriously. A ro ugh estimation shows that out of a population of 1.2 × 10 8 in liver cancer areas patients are more than 1.0 × 10 5 . The environment of the liver cancer area is ...

ISSN 1007-9327 CN 14-1219/R WJG, 1998;4(6):471-474 471 Clinical research advances in primary liver cancer WU Meng-Chao Subject headings liver neoplasms/surgery; hepatectomy; liver neoplasms/therapy Primary liver cancer (PLC) is one of the most common cancers in China. According to the statistics of our country, primary liver cancer claims 20-40 lives per100 000 people annually, with 19.98 per100 000 in cities and 23.59 per 100 000 in rural areas, ranking as the second and the first leading cause of cancer death respectively. Of all the newly enrolled cases in the world each year, 45% are found in the mainland of China. In the southeast areas of high incidence, the situation is even worse that the tumor tends to occur in a younger age group. In China, the research in the diagnosis and treatment of primary liver cancer has undergone four stages: ...

liver cancer Page 1 Growth-inhibiting effects of taxol on human liver cancer in vitro and in nude mice Jin Hui Yuan 1 , Ru Ping Zhang 1 , Ru Gang Zhang 1 , Li Xia Guo 1 , Xing Wang Wang 1 , Dan Luo 2 , Yong Xie 2 and Hong Xie 1 PO Box 2345, Beijing 100023, China World J Gastroentero, 2000; 6(2):210-215 Fax: +86-10-85381893 World Journal of Gastroenterology E-mail: wjg@wjgnet.com www.wjgnet.com Copyright 2000 by the WJG Press ISSN 1007-9327 Subject headings paclitaxel; liver neoplasms; apoptosis; mitoics; in vitro ; DNA; RNA; microscopy, wection; mice, nude Yuan JH, Zhang RP, Zhang RG, Guo LX, Wang XW, Luo D, Xie Y, Xie H. Growthinhibiting effects of taxol on human ...

Abstract. Des- Á -carboxyprothrombin (DCP), also known as a protein induced by vitamin K absence or antagonist II, is an abnormal prothrombin. The level of serum DCP is used in clinical diagnosis and prognosis of patients with hepato- cellular carcinoma (HCC). Our previous immunohistochemical study showed that DCP is expressed not only in cancer tissues but also in the surrounding non- cancer tissues of HCC patients. However, clinical significance of DCP expression in non- cancer tissues of HCC patients remains unclear. In this study, we examined the relationship between histochemical expression of DCP in cancer and/or non- cancer tissues and the clinical outcome of the HCC patients. A retrospective study was performed of 132 patients each with a single primary HCC nodule. Expression of DCP in tissues was evaluated with immunohistochemical staining using anti-DCP antibody ...

September 2004 Children with Leukaemia Biomarkers of exposure to environmental and endogenous leukaemogens Biomarkers of exposure to environmental and endogenous leukaemogens David Shuker Department of Chemistry The Open University Milton Keynes Page 2 September 2004 Children with Leukaemia Page 3 September 2004 Children with Leukaemia Introduction Introduction • Most cancers are preventable • DNA damage appears to be involved in carcinogenesis • How can we put these two facts together to make progress in the battle against cancer ? Page 4 September 2004 Children with Leukaemia Page 5 September 2004 Children with Leukaemia “Nobody wants dirt on their DNA” ...

Background information regarding Austin Health’s new liver cancer treatment What is the treatment for? Certain advanced and inoperable liver cancers. How does it work? The treatment involves using microscopic radiation beads called SIR-Spheres ® that are injected directly into the liver cancers to destroy tumours within the liver that are otherwise inaccessible and inoperable, while minimising harmful side effects to surrounding healthy tissue. For information on the treatment visit www.sirtex.com Can any one with liver cancer have this treatment? Not everyone is suitable for this treatment and must undergo tests in hospital to determine their suitability. How do I find out if I am suitable for this treatment? Visit www.sirtex.com and printout the information to take to your oncologist ( cancer doctor) to discuss your options. ...

All-Ireland cancer statistics 1994-96 50 Liver and intrahepatic bile ducts 8. MALIGNANT CANCER OF THE LIVER AND INTRAHEPATIC BILE DUCTS (summary) ICD-O.2 C22 ICD-10 C22 ICD-9 155 Key facts • Average of 113 new cases per year, 1994-96: 43 cases in females, 70 in males. • Average of 192 deaths per year: 80 in females, 112 in males. • Age-standardised incidence and mortality rates about twice as high in males as in females. • 11th most common cause of cancer deaths in males, 12th in males. • Incidence rates in Northern Ireland (NI) about 130% higher for females, 50% for males, than the Republic (RoI). • Incidence rates well below EU 1995 averages. Summary statistics Table 8.1 Incidence 1994-96 Primary, malignant cancer of the liver and intrahepatic bile ducts is uncommon. On average each ...

The 1997-2001 average annual age-adjusted incidence rate for invasive cancers of the liver and intrahepatic bile duct was almost three times higher in males than in females (7.1 compared to 2.4 per 100,000), and blacks of both sexes had rates that were more than twice as high as the comparable rates for whites. There were 632 cases of liver /intrahepatic bile duct cancers diagnosed and reported among residents of Pennsylvania for 2001. This was the second highest annual figure recorded between 1992 and 2001. The annual age-adjusted incidence rates by sex and race for ten years (1992 through 2001) showed increasing rates among males, especially black males, and females of both races. The 1997-2001 average annual age-specific incidence rates show that black males have usually had the highest risks. During the period of 1997-2001, nearly 61 percent of the cases were diagnosed among residents 65 years of age or older. In 2001, over 46 ...

PO Box 2345, Beijing 100023, China World J Gastroenterol 2004;10(13):1867-1871 Fax: +86-10-85381893 World Journal of Gastroenterology E-mail: wjg@wjgnet.com www.wjgnet.com Copyright © 2004 by The WJG Press ISSN 1007-9327 • LIVER CANCER • Endostatin gene therapy for liver cancer by a recombinant adenovirus delivery Li Li, Jia-Ling Huang, Qi-Cai Liu, Pei-Hong Wu, Ran-Yi Liu, Yi-Xin Zeng, Wen-Lin Huang Li Li, Jia-Ling Huang, Ran-Yi Liu, Pei-Hong Wu, Yi-Xin Zeng, Wen-Lin Huang, Cancer Center, Sun Yat-sen University, 651 Dongfeng RoadEast, Guangzhou 510060,GuangdongProvince,China Qi-Cai Liu, Experimental Medical Research Center, Guangzhou Medical College, 195 Dongfeng Road West, Guangzhou 510182, Guangdong Province, China Supported by the National High Technology Research and Development Program of China (863 Program), No. 2003AA216061 ...

INTRODUCTION The use of alternative therapy in cancer patients has become increasingly popular, although this approach has not been scientifically tested and has the potential to interact with con- ventional treatment (1-6). To date, there have been no studies prospectively investigating the use of alternative therapies in breast cancer patients receiving adjuvant chemotherapy, or determining the risk of abnormal liver function in concomi- tantly treated patients. Also, there are few published reports focusing on hepatotoxicity from chemotherapy with adriamy - cin or the CMF (cytoxan+methotrexate+5-fluorouracil) regi- men in adjuvant chemotherapy trial (7, 8). We previously found that 34% of patients who had received adjuvant adri- amycin followed by CMF chemotherapy for breast cancer developed abnormal liver functions (9). Since many of our patients were also taking various kinds of ...

INTRODUCTION Ginseng has been used as a medicinal plant for more than 2000 yr in Asian countries. In fact, various pharmacological activities have been found in ginseng extract or its consti- tuents. Among them, anti-carcinogenic effect seems to be especially important, since development of effective method for cancer prevention is urgent problem not only in Asian countries but also in all over the world. Inhibitory effect of red ginseng extracts on pulmonary carcinogenesis has already been well documented (1). And tendency of suppression on liver carcinogensis has also reported (1). Thus, at first, we have extended the study on inhibitory effect of red ginseng extracts in liver carcinogensis using other experimental mod- els. Furthermore, anti-carcinogenic activity of white gin- seng extracts, besides red ginseng extracts, was also investi- gated. MATERIALS AND METHODS ...

PO Box 2345, Beijing 100023, China World J Gastroenterol 2004;10(10):1402-1408 Fax: +86-10-85381893 World Journal of Gastroenterology E-mail: wjg@wjgnet.com www.wjgnet.com Copyright © 2004 by The WJG Press ISSN 1007-9327 • LIVER CANCER • Construction of human liver cancer vascular endothelium cDNA expression library and screening of the endothelium-associated antigen genes Xing Zhong, Yu-Liang Ran, Jin-Ning Lou, Dong Hu, Long Yu, Yu-Shan Zhang, Zhuan Zhou, Zhi-Hua Yang Xing Zhong, Yu-Liang Ran, Dong Hu, Long Yu, Yu-Shan Zhang, Zhuan Zhou, Zhi-Hua Yang , Department of Cell and Molecular Biology, Cancer Institute (Hospital), Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing ,100021, China Jin-Ning Lou, Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing 100029, China Supported ...

PO Box 2345, Beijing 100023, China World J Gastroenterol 2004;10(9):1246-1249 Fax: +86-10-85381893 World Journal of Gastroenterology E-mail: wjg@wjgnet.com www.wjgnet.com Copyright © 2004 by The WJG Press ISSN 1007-9327 • GASTRIC CANCER • Role of nucleostemin in growth regulation of gastric cancer , liver cancer and other malignancies Si-Jin Liu, Zi-Wei Cai, Ya-Jun Liu, Mei-Yu Dong, Li-Qiu Sun, Guo-Fa Hu, Ying-Yun Wei, Wei-De Lao Si-Jin Liu, Guo-Fa Hu, Ying-Yun Wei, Wei-De Lao, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100080, China Zi-Wei Cai, Li-Qiu Sun, Institute of Biology of Self-protection, Mudanjiang Medical College, Mudanjiang 157011, Heilongjiang Province, China Ya-Jun Liu, Department of Spine, Beijing Jishuitan Hospital, Peking University, Beijing 100035, China Mei-Yu Dong, Tianjin ...

Rachel's Environment & Health News #73 - Study Of Dioxin-Exposed Humans Reveals Cancer , Birth Defects, Liver And Cardiovascular Damage April 17, 1988 A new study of Vietnam veterans, conducted by Air Force physicians, links dioxin exposure to increases in cancer , birth defects, psychological damage, liver damage, cardiovascular deterioration, and degeneration of the endocrine system. The new work stops short of saying dioxin exposures CAUSED the observable health damage among dioxin-exposed vets, but it explicitly reverses the conclusions of a 1984 Air Force study which said dioxin exposures had been shown to be harmless. The study is continuing, and will begin using sensitive new blood tests to determine past exposures to dioxin; future study may be able to pin down, or rule out, direct causal effects. In the meantime, advocates of mass burn incinerators and other dioxinproducing ...

Abstract. We have demonstrated anti-proliferation and anti-metastasis effects of both interferon- · and a histone deacetylase inhibitor, sodium butyrate, on human liver cancer cell lines. In this study, invasive ability of human liver cancer cell lines through the matrix-coated membrane was examined and inhibitory effect of interferon- · and sodium butyrate was investigated. Among six human liver cancer cell lines, HLE and HLF showed high invasive ability using the Matrigel invasion assay. This invasion ability was significantly inhibited by pretreatment of the cells with 1000 IU/ml of interferon- · or 2 mM of sodium butyrate. Gelatin zymography and the matrix metalloproteinase-2 and -9 activity assay showed that these two cell lines produce active- and pro-matrix metalloproteinase-2 and -9, and their activity was significantly reduced by ...

PO Box 2345, Beijing 100023, China World J Gastroenterol 2004;10(5):654-659 Fax: +86-10-85381893 World Journal of Gastroenterology E-mail: wjg@wjgnet.com www.wjgnet.com Copyright © 2004 by The WJG Press ISSN 1007-9327 • LIVER CANCER • Anti- liver cancer activity of TNF-related apoptosis-inducing ligand gene and its bystander effects Chao He, Wei-Feng Lao, Xiao-Tong Hu, Xiang-Ming Xu, Jing Xu, Bing-Liang Fang Chao He, Wei-Feng Lao, Xiao-Tong Hu, Jing Xu, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310016, Zhejiang Province, China Xiang-Ming Xu, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China Bing-Liang Fang, Department of Thoracic and Cardiovascular Surgery, M.D. Anderson Cancer Center, Huston, 77030, USA Supported by the National Natural ...

Genetic Profiling of Colorectal Cancer Liver Metastases by Combined Comparative Genomic Hybridization and G-Banding Analysis Chieu B. Diep, 1 Luis A. Parada, 2 Manuel R. Teixeira, 3 Mette Eknæs, 1 Jahn M. Nesland, 4 Bertil Johansson, 2 and Ragnhild A. Lothe 1 * 1 Department of Genetics, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo, Norway 2 Department of Clinical Genetics, Lund University Hospital, Lund, Sweden 3 Department of Genetics, Portuguese Oncology Institute, Porto, Portugal 4 Department of Pathology, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo, Norway The majority of genetic studies of colorectal carcinogenesis have focused on changes found in primary tumors. Despite the ...

Abstract. To uncover mechanisms underlying progression of colorectal carcinogenesis and to identify genes associated with liver metastasis, we analyzed expression profiles of 14 primary colorectal cancers (CRCs) with liver metastases, and compared them with profiles of 11 non-metastatic carcinomas and those of 9 adenomas of the colon. A hierarchical cluster analysis using data from a cDNA microarray containing 23,040 genes indicated that the cancers with metastasis had different expression profiles from those without metastasis, although a number of genes were commonly up-regulated in primary cancers of both categories. We documented 54 genes that were frequently up-regulated and 375 that were frequently down-regulated in primary tumors with metastases to liver , but not in tumors without metastasis. Subsequent quantitative PCR experiments confirmed that PRDX4, CKS2, MAGED2 , and an EST (GenBank ...

74 A SYSTEM FOR THE TREATMENT OF LIVER CANCER BY TARGETED HYPERTHERMIA USING MAGNETIC MICROSPHERES S. K. Jones 1 P. Moroz 2 and B. N. Gray 1 1 Sirtex Medical Ltd, North Ryde, NSW 1670, Australia, 2 University of Western Australia, Crawley, WA 6009, Australia ABSTRACT: Sirtex Medical Limited is developing new technology to treat liver cancer by induced hyperthermia using magnetic microspheres. Eighty to ninety percent of patients presenting with primary or secondary liver cancer have inoperable disease and a poor prognosis [1-4]. The median survival for patients with non-resectable hepatocellular carcinoma is three to six months [5,6], and six to 12 months for patients with non-resectable hepatic colorectal metastases [7]. These patients must rely largely on various forms of chemotherapy, radiotherapy ...

Cancer of the Liver Liver cancer can be due to malignant changes in the liver cells themselves—called primary liver cancer—or it can be due to a cancer spreading from another site to the liver—called secondary liver cancer. This message focuses on primary liver cancer, and does not address secondary liver cancer. Cancer that has spread to the liver from another site retains the characteristics and behavior of the original tumor—whether it is breast, colon, pancreatic, stomach, or some other cancer. In North and South America and in Europe, primary liver cancers account for only one to two percent of malignant tumors. However, in parts of Africa and Asia, they are much more common, accounting for 20 to 30 percent of malignancies. Liver cancer is four times as common in men as in women. In Western countries, it occurs most commonly in people in their 40s and 50s, but in Africa and Asia it may occur one or two decades ...

P.O.Box 2345, Beijing 100023, China World J Gastroenterol 2003;9(4):706-709 Fax: +86-10-85381893 World Journal of Gastroenterology E-mail: wjg@wjgnet.com www.wjgnet.com Copyright © 2003 by The WJG Press ISSN 1007-9327 • LIVER CANCER • Right trisectionectomy for primary liver cancer Jing-An Rui, Shao-Bin Wang, Shu-Guang Chen, Li Zhou Jing-An Rui, Shao-Bin Wang, Shu-Guang Chen, Li Zhou, Department of General Surgery, Peking Union Medical College Hospital, Beijing 100032, China Correspondence to: Prof. Jing-An Rui, Department of General Surgery, Peking Union Medical College Hospital, Beijing 100032, China. rlzhou@mail.bjmu.edu.cn Telephone: +86-10-62091034 Fax: +86-10-62358270 Received: 2002-11-19 Accepted: 2003-01-02 Abstract AIM: To evaluate the value of right trisectionectomy, previously named right trisegmentectomy, ...

P.O.Box 2345, Beijing 100023,China World J Gastroenterol 2003;9(2):193-200 Fax: +86-10-85381893 World Journal of Gastroenterology E-mail: wjg@wjgnet.com www.wjgnet.com Copyright © 2003 by The WJG Press ISSN 1007-9327 • REVIEW • Current treatment for liver metastases from colorectal cancer Lian-Xin Liu, Wei-Hui Zhang, Hong-Chi Jiang Lian-Xin Liu, Wei-Hui Zhang, Hong-Chi Jiang, Department of Surgery, the First Clinical College, Harbin Medical University, Harbin 150001, Heilongjiang Province, China Supported by Youth Natural Science Foundation of Heilongjiang Province Correspondence to: Dr Lian-Xin Liu, Department of Surgery, First Clinical College, Harbin Medical University, No. 23 Youzheng Street, Nangang District, Harbin 150001, Heilongjiang Province, China. liulianxin@sohu.com Telephone: +86-451-3643849-5885 Fax: +86-451-3670428 ...

• Active liver disease (jaundice) • Breast lumps and possible breast cancer • Migraines • Diabetes • Hypertension If none of these are found Depoprovera may be given. If there are any “Yes” answers, you should carefully consider the risks and benefits of Depoprovera use for the particular client. Timing of injection Injectable contraceptives should be given: • Within the first 7 days of the menstrual cycle • Any time during the menstrual cycle if it is certain that the woman is not pregnant. She has no signs or symptoms of pregnancy (e.g. breast tenderness, nausea) and: • Has not had sexual intercourse since her last menses, or • Has been using another reliable contraceptive method consistently and correctly • After the 7th day, only with a back up method preferably condoms, which should be used for 24 hours Postpartum • Breastfeeding mothers: If the women is ...

P.O.Box 2345, Beijing 100023,China World J Gastroenterol 2003;9(10):2341-2343 Fax: +86-10-85381893 World Journal of Gastroenterology E-mail: wjg@wjgnet.com www.wjgnet.com Copyright © 2003 by The WJG Press ISSN 1007-9327 • BRIEF REPORTS • Effect of resveratrol on cell cycle proteins in murine transplantable liver cancer Liang Yu, Zhong-Jie Sun, Sheng-Li Wu, Cheng-En Pan LiangYu, Zhong-JieSun,Sheng-LiWu,Cheng-EnPan, Department of Hepatobiliary Surgery, First Hospital of Xi’an Jiaotong University, Xi’an 710061, Shaanxi Province, China Supported by Traditional Chinese Medicine Bureau Foundation of Shaanxi Province, No. 2001-035 Correspondence to: Dr. Liang Yu, Department of Hepatobiliary Surgery, First Hospital of Xi’an Jiaotong University, Xi’an 710061, Shaanxi Province, China. yuliang@163.com Telephone: +86-29-5324009 Received: ...