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Select Journal or Resource Vol. 294 No. 12, September 28, 2005 Featured Link • E-mail Alerts Original Contribution Effect of Smoking Reduction on Lung Cancer Risk Nina S. Godtfredsen, MD, PhD; Eva Prescott, MD, DMSc; Merete Osler, MD, PhD, DMSc JAMA. 2005;294:1505-1510. Context Many smokers are unable or unwilling to completely quit smoking. A proposed means of harm reduction is to reduce the number of cigarettes smoked per day. However, it is not clear whether this strategy decreases the risk for tobacco-related diseases. Objective To assess the effects of smoking reduction on lung cancer incidence. Design, Setting, and Participants Observational population-based cohort study with up to 31 years of follow-up from the Copenhagen Centre for Prospective Population Studies, which administrates data from 3 longitudinal studies conducted in Copenhagen and suburbs, ...

Incidence and Mortality Rate Trends Lung cancer is the second most common cancer and the most common cause of cancer -related death in both men and women in the United States. The overall mortality rate for lung and bronchus cancer rose steadily through the 1980s and peaked around 1990. While incidence and mortality rates for men have dropped in the last decade, this trend has not been observed for women. Mortality rates are highest among African American males, followed by White males. It is estimated that approximately $9.6 billion* is spent in the United States each year on treatment of lung cancer . *In 2004 dollars, as reported in Brown ML, Riley GF, Schussler N, and Etzioni RD. Estimating health care costs related to cancer treatment from SEER-Medicare data. Medical Care 2002 Aug; 40 (8 Suppl): IV-104-17. Source for incidence ...

888 16th Street NW Suite 800 Washington DC 20006 202-463-2080 800-298-2436 hotline lungcanceralliance.org NO MORE EXCUSES. NO MORE LUNG CANCER . Lung cancer is the leading cause of cancer death in the United States. Lung cancer causes 30% of all cancer deaths. Lung cancer is the leading cancer killer among Caucasians, African-Americans, Asians and Hispanic males. Lung cancer will kill more people this year than: • breast cancer • prostate cancer • colon cancer • liver cancer • kidney cancer • melanoma combined Lung cancer will kill 3 times as many men as prostate cancer this year. Lung cancer will kill nearly twice as many women as breast cancer this year. Over 50% of new lung cancer cases will be diagnosed at a very late stage—Stage IIIb or IV—and only 5% of them will ...

September 2, 2005 LUNG CANCER ALLIANCE TAKES LANDMARK ACTION; SEEKS LUNG CANCER RESEARCH AND EARLY DETECTION FUND FROM TOBACCO INDUSTRY The Lung Cancer Alliance (LCA) took landmark action today by requesting leave to file an Amicus Brief before the United States District Court to add lung cancer research and early detection to the remedies that the court is considering in the case of the United States of America vs. Philip Morris, USA, Inc and other tobacco companies. The court is currently considering only funding for tobacco control and smoking cessation programs as remedies to prevent and restrain future wrongdoing by the tobacco company defendants. In the brief, LCA argues that in addition to these remedies, the defendants should be required to contribute to a fund to support independent scientific research on the aetiology, diagnosis, treatment and cure of lung cancer ...

(formalin fixed) A716: Test slide - Lung cancer tissues with corresponding normal tissues For research use only Specifications: • No. of cases: 6 • Tissue type: Test slide, lung cancer tissues with corresponding normal tissues • No. of spots: 1 spot from each cancer case (6 spots) 6 non-neoplastic spots (6 spots) • Total spots: 12 • Corresponding normal tissues with cancers: Yes • Diameter: 1. 0 mm Documents : • Product specification: layout, summary of tissue spots • H&E stained images • Detailed pathological information Layout: Page 2 (formalin fixed) A716: Test slide - Lung cancer tissues with corresponding normal tissues For research use only Summary of tissue spots No. Coordinate Sex Age Organ KeyWord 1 ...

The Australian Lung Foundation / Lung Cancer Consultative Group Travel Awards Four travel awards in the amount of $500 each will be granted to Advanced Trainees, clinical nurses or allied health professionals to attend the inaugural Australian Lung Cancer Conference, hosted by the Australian Lung Foundation on 30 June-2 July 2006 in Cairns, Queensland. Four similar awards are being offered in the names of the four founding sponsors of the Australian Lung Foundation’s Lung Cancer Consultative Group: Sanofi Aventis Award ($500), Eli Lilly Award ($500), AstraZeneca Award ($500), and Bristol-Myers Squibb Award ($500). Each award will also include complimentary delegate registration to the Conference. The awards are open to Advanced Trainees, registered clinical nurses and allied health professional working at any recognized Australian health care facility. Priority will be given to those submitting ...

Lung Cancer Information The Marie Keating Foundation has been established to provide cancer information and awareness free of charge to general public throughout Ireland. Our Units carry information on Breast, Testicular, Prostate, Bowel, Lung , Skin and Cervical cancer . Our service is provided through our registered Nurses on board the Units, leaflet information, teaching aids, presentations, exhibitions and seminars. The Marie Keating Foundation offers Medical and Nursing Scholarships. Our future projects include Marie Keating Foundation waiting rooms within Cancer Care Hospitals. As the Marie Keating Foundation is not government funded we depend on private and corporate donations. We at the Marie Keating Foundation would like to thank Breast Check, The Irish Cancer Society, Action Cancer Northern Ireland, Cancer Research UK and health care professionals specializing ...

1 S2M-2003 Lung Cancer Awareness Month RCN SCOTLAND PARLIAMENTARY BRIEFING Introduction It is estimated that one in three people in Scotland will develop some form of cancer during their lifetime. Lung cancer is the most common form of cancer in Scotland and smoking is its primary cause, estimated to account for around 90% of all cases. If a person stops smoking, the risk of lung cancer goes down quite quickly. There is also an increasing body of evidence to show that passive smoking increases the risk of lung disease and cancer . It also effects people disproportion- ately in terms of social class, with those from areas of high social deprivation twice as likely to be diagnosed with lung cancer as those from the least deprived areas. Those from less deprived areas are also more likely ...

***MEDIA ADVISORY*** XYOTAX™ New Drug Application On behalf of lung cancer patients, survivors, their caregivers, and those at risk for the disease, the Lung Cancer Alliance is encouraged to learn of Cell Therapeutics Inc.’s (CTI) decision to submit a new drug application (NDA) for XYOTAX to target survival in women with lung cancer . “We applaud CTI for its interest in better understanding this devastating disease – since lung cancer patients are faced with so few treatment options,” said Laurie Fenton, President of the Lung Cancer Alliance. “While we recognize that there are many more steps to go in this process before we learn for certain whether this drug will improve survival rates for women – we are heartened that CTI would take such initiative. We will continue to monitor this research closely.” Lung cancer will kill nearly twice as many women as breast cancer this year. More research ...

Lung Cancer Can Strike Nonsmokers Dana Reeve, widow of Christopher Reeve, highlights growing incidence of malignancy unconnected to smoking By Amanda Gardner HealthDay Reporter WEDNESDAY, Aug. 10 (HealthDay News) -- The news that Dana Reeve, the widow of "Superman" actor Christopher Reeve, has lung cancer proves the disease can -- and does -- strike anyone. She is only 44 years old. And never smoked. Her revelation Tuesday followed by two days the lung - cancer death of ABC news anchor P Jennings at age 67. eter Jennings was both a smoker and an ex-smoker: He quit for 20 years but admitted starting again after the Sept. 11, 2001, terrorist attacks. While Jennings' ordeal was probably due to cigarettes, Reeve's struggle is less understandable. Some 85 percent to 90 percent of lung cancer cases occur in smokers, said Dr. Ruth Oratz, an associate professor ...

WOMEN’S HEALTH in Primary Care Vol. 8, No. 3/APRIL 2005 149 T he American Cancer Society estimates that about 46% of new lung cancers in 2005 will be in women 1 —a statistic that seems unre- markable until one considers that just 30 years ago the disease was more than three times as common in men as in women. Yet although the de- gree to which women have “caught up” to men in- evitably inspires ironic references to the old “You’ve come a long way, baby” cigarette ad slogan, a recent analysis of national epidemiologi- cal data by Fu and colleagues 2 does reveal some mildly encourag- ing trends regarding lung cancer in women—depending on one’s per- spective. Below, we examine some of these trends, from both a glass- half-empty and a glass-half-full point of view. L UNG CANCER INCIDENCE ...

MRSEC The Internships in Public Science Education program ( ipse@chem.wisc.edu ) is funded by a grant from the National Science Foundation. This program is a collaboration between the University of Wisconsin Materials Research Science and Engineering Center on Nanostructured Materials and Interfaces and the James Lovell Museum of Science, Economics & Technology in Milwaukee, Wisconsin All materials are copyright © 2002 The Board of Regents of the University of Wisconsin System. Attention Scientists: New Lung Cancer Treatment Needed A patient has lung cancer and she has tried various treatments to cure her cancer including chemotherapy and homeopathic therapies. Her cancer is very resistant to traditional treatments. A new cancer drug has been developed and looks very promising for curing lung cancer resistant to current treatments. However, this drug is very harmful to many ...

Where to Start Sources of Information on Lung Cancer Suggestions for resources when you begin to look for information about lung cancer . Prepared by the Ninon Bourque Patient Resource Library The Ottawa Hospital Regional Cancer Centre 501 Smyth Road, Ottawa, ON, K1H 8L6 613-737-7700 ext 70107 These resources are provided for information purposes only and are not intended as a substitute for medical care. Inclusion of a resource does not imply endorsement by The Ottawa Hospital. If you have any questions about your healthcare, please consult your healthcare provider. If you would like to have more information about this topic, please contact the Ninon Bourque Patient Resource Library at 613-737-7700 ext. 70107 or consumerhealth@ottawahospital.on.ca . Brochure Lung cancer : what you need to know . An 11-page booklet providing information about lung cancer ...

The Impact of PET on the Management of Lung Cancer : The Referring Physician’s Perspective Marc A. Seltzer, MD 1 ; Cecelia S. Yap, BS 1 ; Daniel H. Silverman, MD, PhD 1 ; Joubin Meta, BS 1 ; Christiaan Schiepers, MD, PhD 1 ; Michael E. Phelps, PhD 1 ; Sanjiv S. Gambhir, MD, PhD 1 ; Jyotsna Rao, MD 2 ; Peter E. Valk, MD 2 ; and Johannes Czernin, MD 1 1 Department of Molecular and Medical Pharmacology, Ahmanson Biological Imaging Clinic/Nuclear Medicine, UCLA School of Medicine, Los Angeles, California; and 2 Northern California PET Imaging Center, Sacramento, California 18 F-FDG PET is a molecular whole-body imaging modality that is increasingly being used for diagnosing, staging, and restaging cancer . The ...

254 · July 27, 2000 The New England Journal of Medicine PREOPERATIVE STAGING OF NON–SMALL-CELL LUNG CANCER WITH POSITRON-EMISSION TOMOGRAPHY R EMGE M. P IETERMAN , M.D., J OHN W.G. VAN P UTTEN , M.D., J ACOBUS J. M EUZELAAR , M.D., E DUARD L. M OOYAART , M.D., W ILLEM V AALBURG , P H .D., G ERARD H. K OËTER , M.D., V ACLAV F IDLER , P H .D., J AN P RUIM , M.D., AND H ARRY J.M. G ROEN , M.D. A BSTRACT Background Determining the stage of non–small- cell lung cancer often requires ...

Center for Environmental Health Studies (617) 482-9485 44 Farnsworth Street, Boston, MA 02210 http://www.jsi.com Lung Cancer and Exposure to Ionizing Radiation 1 Lung Cancer and Exposure to Ionizing Radiation Summary : Studies conducted at the Los Alamos National Laboratory and other nuclear facilities suggest an increased likelihood of developing lung cancer for workers who have been exposed to ionizing radiation. These findings are consistent with the determination of the National Research Council’s BEIR V committee that lung tissue if sensitive to ionizing radiation. Lung cancer is a “specified” cancer under the Energy Employees Occupational Illness Compensation Program Act. Historically, lung cancer incidence and mortality ranked among the lowest in the state for both Los Alamos and Rio Arriba Counties. Incidence means new cases of ...

Radon and Lung Cancer in New Hampshire Making The Connection Making The Connection for Risk Communication for Risk Communication Megan Tehan, Epidemiologist Megan Tehan, Epidemiologist Matthew Cahillane, Program Manager Matthew Cahillane, Program Manager April 22, 2005 April 22, 2005 Page 2 Presentation Overview What is radon? What is radon? What are its health effects? What are its health effects? Awareness, attitudes and actions of Awareness, attitudes and actions of NH citizens NH citizens Associating radon with lung cancer for Associating radon with lung cancer for better risk communication better risk communication Page 3 What is Radon? Radioactive gas Radioactive ...

Copyright Priory Lodge Education Ltd. 2005 First Published 17 th June 2005 Case report : pineal metastasis from lung cancer Dr. K.W. Lam 1 MRCS , Dr F C Cheung 2 FRCS , FHKAM , Dr K M Ko 1 FRCS , FHKAM Department of Cardiothoracic Surgery 1 ,Department of Neurosurgery 2 , Queen Elizabeth Hospital, 30 Gascoigne Road, Hong Kong. Correspondence : Dr K.W. Lam , fax : 00852- 2958-5673 , email : pkwlam1@yahoo.com Department of Cardiothoracic Surgery, Queen Elizabeth Hospital , 30 Gascoigne Road, Kowloon, Hong Kong Running title Metastasis to the pineal gland from carcinoma of lung are rare. 2 This is a case report of a 57 year old lady presented with progressive diplopia, nausea and headache. CT brain revealed pineal metastasis from ...

Pharmacor NON-SMALL-CELL LUNG CANCER Page 2 Non-Small-Cell Lung Cancer Pharmacor 2 YOU NEED TO KNOW: How are treatment paradigms evolving in non-small-cell lung cancer (NSCLC)? In light of recent clinical trial evidence, what is the future of gefitinib in this market? How will novel agents be incorporated into current treatment regimens? INTRODUCTION: The marketplace for therapies to treat NSCLC, one of the most common and deadly forms of cancer , is undergoing rapid change. Our research has revealed three major forces that will continue to drive market expansion: an increase in the number of patients deemed eligible for chemotherapy; the rapid uptake of novel targeted therapies; and increasing use of newer, branded agents in chemotherapy regimens. Despite recent advances in treatment, however, NSCLC carries a huge burden ...

Lung Cancer Lung cancer is the leading cause of cancer deaths for both men and women — an estimated 163,510 people will die of lung cancer in 2,005. But death rates are declining in both men and women. Tobacco use is the most important risk factor for lung cancer . PREVENTION • Don’t use tobacco in any form. • If you use tobacco, quit. • Create smoke-free environments in your community. RISK • People who use tobacco in any form • People who have had exposure to substances such as arsenic, radon and asbestos People whose occupation exposes them to radiation • People exposed to second-hand smoke • All people exposed to air pollution and environmental smoke SYMPTOMS In the early stages, there may be no symptoms. Later these signs may appear: • Persistent cough • Sputum (spit) streaked with blood • Chest pain • Recurring pneumonia or ...

TRENDS IN LUNG CANCER MORBIDITY AND MORTALITY AMERICAN LUNG ASSOCIATION EPIDEMIOLOGY AND STATISTIC UNIT RESEARCH AND PROGRAM SERVICES MAY 2005 Page 2 TABLE OF CONTENTS Trends in Lung Cancer Morbidity and Mortality Introduction Lung Cancer Mortality Trends, 1979-2002 Lung Cancer Incidence Trends, 1973-2002 Lung Cancer Trends in Hospital Discharges, 1979-2002 Lung Cancer Survival Rates Trends, 1960-2001 Lung Cancer Types and Stage Distribution, 1995-2001 Smoking-Attributable Lung Cancer Deaths, 1997-2001 Lifetime Risk of Being Diagnosed with and Dying from Lung Cancer , 2000-2002 References List of Tables Table 1: Lung Cancer : Number of Deaths By Race and Sex, 1979-1998, 1999-2002 Table 2: Lung Cancer : Age-Adjusted Mortality Rates By Race and Sex, 1979-1998, 1999-2002 Table 3: Lung ...

TRENDS IN LUNG CANCER MORBIDITYAND MORTALITY PART II GRAPHS AMERICAN LUNGASSOCIATION EPIDEMIOLOGY & STATISTICS UNIT RESEARCH AND PROGRAM SERVICES MAY 2005 Page 2 30 35 40 45 50 55 60 65 Ag e Ad ju st ed Deat h Rat e p e r 100,000 Perso n s 1940 2000 1979 1980 1981 1982 1983 1984 1985 1986 1987 1988 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 33.6 34.8 35.1 35.9 36.4 37.0 37.6 37.8 38.5 38.8 39.3 39.9 39.6 39.3 39.3 38.7 38.3 37.9 37.3 37.0 35.7 35.9 34.8 34.4 47.8 49.8 50.3 51.7 52.6 53.6 54.6 55.2 56.4 57.1 58.1 59.3 ...

MARK K. FERGUSON, M.D. Professor, Cardiac & Thoracic Surgery The Role of the Surgeon in Diagnosing and Treating Lung Cancer Since the first successful resections were performed for lung cancer 75 years ago, substantial progress has been made in the surgical management of lung cancer . As a result, despite numerous advances in our understanding of the pathobiology of this disease and the resultant development of therapies, surgery remains one of the mainstays of curative therapy for lung cancer . Techniques such as flexible fiberoptic bronchoscopy and sputum cytology remain the basic tools for lung cancer diagnosis.Advances in radiology have led to the introduction of low dose helical computed tomography for screening for lung cancer , which is effective in identifying small lung nodules not evident on plain chest radiographs. Such nodules are not amenable to bronchoscopic biopsy, ...

7 Minimally Invasive Approaches to Surgery for Lung and Esophageal Cancer Mark K. Ferguson, MD Professor, Section of Cardiac and Thoracic Surgery Department of Surgery University of Chicago (773) 702-3551 mferguso@surgery.bsd.uchicago.edu Video-assisted thoracic surgery (VATS) was introduced in the late 1980s to facilitate lung biopsy, pleural procedures, and a variety of other small operations that traditionally were done through an open thoracotomy. Since then, the scope of VATS has expanded to include more major procedures such as resection of mediastinal tumors, thoracic spine surgery, and operations for benign esophageal disease. During the past 5 years, a few pioneers have used VATS techniques to perform lobectomy and esophagectomy for cancer . These efforts have been controversial because of concerns over whether use of these ...

Key statistics on smoking • Cigarette smoking remains the single largest cause of preventable death and disease in Australia. Tobacco is a major risk factor for several cancers, chronic obstructive pulmonary disease, cardiovascular diseases, respiratory diseases, asthma, low birth weight babies and sudden infant death syndrome. 1 • In Western Australia, the Department of Health has estimated that in 2001, tobacco caused 1445 premature deaths from smoking-related illness. 2 It is estimated that in 1998-1999, the direct and indirect costs of tobacco use to the Western Australian community were $1.6 billion. 3 • Over the last 20 years, the prevalence of smoking among adults in Western Australia decreased from 32% in 1984 to around 19% in 2001. 4 • Research shows that about a half of all persistent ...

Lung Cancer When it comes to cancer , knowledge is good medicine. More men and women die of lung cancer than any other type of cancer in the United States. In recent years, more women have died from lung cancer than even breast cancer , because more women continue to smoke. Cigarette smoking is by far the most important preventable cause of lung cancer . Tobacco is linked to 87 percent of all lung cancer cases. Other factors include exposure to: • Industrial substances (such as chemicals and asbestos) • Radiation exposure from occupational, medical and environmental sources • Air pollution • Radon exposure People who smoke cigarettes and have exposure to other risk factors have an even greater chance of developing cancer of the lung . Second-hand tobacco smoke increases lung cancer risk for nonsmokers. The good news is studies show that after quitting, damaged lung tissue ...

1 LUNG CANCER SUMMARY INTRODUCTION WHO GETS LUNG CANCER ? WHAT ARE THE MORTALITY AND SURVIVAL FIGURES FOR LUNG CANCER ? HOW HAVE LUNG CANCER INCIDENCE AND MORTALITY CHANGED OVER TIME? WHAT ARE THE RISK FACTORS FOR LUNG CANCER ? HOW CAN LUNG CANCER BE PREVENTED OR CONTROLLED? WHERE TO FIND MORE INFORMATION DEFINITIONS INTRODUCTION More than 3,100 Wisconsin residents were diagnosed with lung cancer and 2,660 residents died from lung cancer in 2000 (Table 1). Lung cancer is the second most common cancer among women (second to breast cancer ) and men (second to prostate cancer ) and is the leading cause of cancer deaths in Wisconsin. This paper summarizes information about primary lung cancer incidence, mortality, risk factors, prevention and current research. Table 1. Lung Cancer Incidence and ...

•Secondhand smoke, also called Environmental Tobacco Smoke (ETS), is recognized as the third preventable cause of death in the U.S., preceded by active smoking and alcohol consumption. [1] •Secondhand smoke exposure at home, work, or both combined is asso- ciated with fatal coronary heart disease. [2] More than 35,000 heart disease deaths can be attributed to secondhand smoke. [3] •Annually secondhand smoke is responsible for an estimated 3000 lung cancer deaths, 35,000 cardiovascular disease deaths, and 2,300 sudden infant deaths. [4] •The Environmental Protection Agency (EPA) estimates that annually, there are 26,000 new cases of asthma in children and 300,000 cases of bronchi- tis and pneumonia in children, which are directly attributable to second hand smoke. [3] •There is a high risk for heart disease for non-smokers married to a current smoker. [2] Never smokers who are currently living with ...

INDIAN JOURNAL OF MEDICAL & PAEDIATRIC ONCOLOGY Vol. 26 No.1, 2005 3 Editorial Approximately one third of all cancer -related deaths are due to lung cancer , which accounts for more deaths each year than breast, prostate, and colon cancer combined. The median survival of patients with untreated metastatic non–small- cell lung cancer (NSCLC) is only four to five months and one year survival rate is about 10 percent. 1 Chemotherapy for advanced NSCLC cancer is often considered ineffective or excessively toxic. However, meta-analysis has demonstrated that compared to supportive care, chemotherapy provides improvement in survival in patients with advanced non–small- cell lung cancer . 2 In addition, randomized studies comparing chemotherapy with the “best supportive care” have shown that chemotherapy reduces symptoms ...