[121]
LYMPHOMA PCP.
[15,8 KB]
From [www.scgh.health.wa.gov.au] Last viewed: 07.09.2006
LYMPHOMA PCP.
ELIGIBILITY CRITERIA
INCLUSION CRITERIA:
To be eligible for inclusion in this trial, all of the below boxes should be ticked.
• Biopsy proven diagnosis of low grade non-Hodgkin’s lymphoma including the following
histological subtypes:
Follicular lymphoma ,
Follicular mixed small-cleaved and large cell,
Diffuse small lymphocytic lymphoma ,
Lymphoplasmacytic lymphoma ,
Splenic marginal zone lymphoma ,
Extranodal marginal zone lymphoma of MALT type,
Nodal marginal zone B-cell lymphoma
Low grade B cell lymphoma not otherwise specified.
• Previously untreated disease.
• Able to undergo study procedures / treatment.
• ECOG performance status grade < 2.
• > 18 years of age.
• Available for follow-up for a minimum of 12 months.
• Able to provide informed consent.
EXCLUSION CRITERIA:
To be eligible for ...
[122]
Microsoft PowerPoint - PathoBiology of Malignant Lymphoma at NCI
[8788,2 KB]
From [www.nci.edu.eg] Last viewed: 07.09.2006
Patho-Biology of
Malignant Lymphoma
at NCI
Nadia Mokhtar, Ph.D.
NCI, Cairo University
Page 2
Prevalence of NHL: rank
among all cancer types
5
th
5
th
USA
3
rd
3
rd
Egypt
11
th
10
th
World
FEMALES
MALES
REGION
Page 3
Page 4
ML
10.1%
Total Malignancy
NHL
HL
69.7%
30.3%
Nodal
70.8%
Extra Nodal
29.2%
Cancer Pathology Registry 1998-2000
(n=1095)
Lymphoma : Leukemia Ratio 1.2:1
Male: Female Ratio 2.5:1
Page 5
T 12%
B88%
Immunophenotyping
Page 6
B
...
[123]
EBMT Lymphoma Registry
[279,7 KB]
From [www.ebmt.org] Last viewed: 07.09.2006
March 2004
Total registrations
46,624
New registrations
6915
(since EBMT 2002)
Total number of centres
522
New centres
12
EBMT Lymphoma Registry
Page 2
March 2004
Lymphoma transplants:
by year of transplant
0
1000
2000
3000
4000
5000
6000
7000
8000
1978 1979 1980 1981 1982 1983 1984 1985 1986 1987 1988 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001
2002+
Year of transplant
No. of transplants
Page 3
March 2004
Lymphoma transplants:
Classical vs reduced intensity conditioning
0
100
200
300
400
500
600
700
800
900
1000
<1995
1995 1996 1997 1998 1999 2000 2001 2002
2003+
Year ...
[124]
Lymphoma book
[7992,3 KB]
From [www.lymphoma.org.uk] Last viewed: 07.09.2006
Page 2
Page 3
1
Acknowledgements
Our thanks to Reta Johnstone and Catriona Gilmour Hamilton
for putting this information together, mostly drawn from the
Lymphoma Association’s booklets ‘Treatment choices in low
grade follicular lymphoma ’ written by Professor John
Sweetenham and ‘Lymphomas’ written by Catriona Gilmour
Hamilton. Patients’ views and some of the quotations included
here were taken from a questionnaire asking people what it is
like to live with follicular lymphoma ; this was carried out by the
Lymphoma Association in 2000.
Thanks also go to our reviewers, Professors Martin Dyer and
John Sweetenham, and Dr Robert Marcus; and to three
individuals with personal experience of lymphoma , Keith and
Aline Nowell and Lesley-Anne Robins.
Sponsor
With grateful thanks to GlaxoSmithKline for assistance with ...
[125]
Mass Youth Soccer and Leukemia & Lymphoma Society Join Teams for ...
[28,2 KB]
From [www.mayouthsoccer.org] Last viewed: 07.09.2006
The official online magazine of the Massachusetts Youth Soccer Association; April 2004
shop adidas.com
Kicks for Cancer
2004 Young Referees
of the Year
KNVB Programs in the
Boston Area
Mass Youth Soccer
Olympic Development
Teams Announced
TOPSoccer News
Prevention of ACL
Injuries
Coach's Clipboard
Soccer News Blurbs
and Blips
Approved
Tournaments
Referee Courses
Mass Youth Soccer and Leukemia & Lymphoma
Society Join Teams for the Fight Against Cancer
Soccer Kicks for Cancer is a soccer development, community outreach and
fundraising program developed by US Youth Soccer and The Leukemia &
Lymphoma Society. Soccer players raise funds for research and patient
programs by getting donations for the
number of “touches” they make on the
soccer ball at home over a ten day
period. ...
[126]
Mass Youth Soccer and Leukemia & Lymphoma Society Join Teams for ...
[36,3 KB]
From [www.mayouthsoccer.org] Last viewed: 07.09.2006
The official online magazine of the Massachusetts Youth Soccer Association; May 2004
shop adidas.com
ODP Mini Camp
Mass Boys ODP Trip
to Portugal
High Performance
Sports: Periodization
Training
Kicks for Cancer
KNVB Programs in the
Boston Area
TOPSoccer - Share
the Joy of Soccer!
Coach's Clipboard
Soccer News Blurbs
and Blips
Approved
Tournaments
Referee Courses
Mass Youth Soccer and Leukemia & Lymphoma
Society Join Teams for the Fight Against Cancer
Soccer Kicks for Cancer is a soccer development, community outreach and
fundraising program developed by US Youth Soccer and The Leukemia &
Lymphoma Society. Soccer players raise funds for research and patient
programs by getting donations for the
number of “touches” they make on the
soccer ball at home over a ten day
period. ...
[127]
LYMPHOMA
[155,2 KB]
From [www.fda.gov] Last viewed: 07.09.2006
LYMPHOMA
RESEARCH
-FOUNDATION
July 30, 2004
The Honorable Lester Crawford, D.V.M, Ph.D
Acting Commissioner
Food and Drug Administration
Parklawn Building
5600 Fishers Lane
Room 1471
Rockville, MD 20857
RE: Docket No. 2004-N-0181
Dear Dr. Crawford:
The Lymphoma Research Foundation (LRF) is the nation’s largest lymphoma -focused voluntary health
organization devoted exclusively to funding lymphoma research and providing patients and healthcare
professionals with critical information on the disease. We appreciate the opportunity to comment on the
report, “Innovation/Stagnation: Challenge and Opportunity on the Critical Path to New Medical
Products,” and to offer recommendations to improve the development of new cancer therapies.
We appreciate FDA’s effort to identify problems in the development of new therapies and to invite
proposals from the public ...
[128]
Lymphoma: Non-Hodgkins Disease - Overview
[15,3 KB]
From [www.cancer.med.umich.edu] Last viewed: 07.09.2006
Lymphoma : Non-Hodgkins Disease - Overview
© copyright 2004 U-M Comprehensive Cancer Center
The University of Michigan Health System web site does not provide specific medical advice and does not
endorse any medical or professional service obtained through information provided on this site or any links
to this site.
Use of the UMHS web site does not replace medical consultation with a qualified health or medical
professional to meet the health and medical needs of you or others.
While the content of the UMHS web site is frequently updated, medical information changes rapidly and
therefore, some information may be out of date, and/or contain inaccuracies or typographical errors.
Lymphoma is the third most common cancer in children in the United States.
Approximately 10 percent of cancers in children less than 15 years of age are
lymphomas. Two broad categories of lymphoma are recognized -- ...
[129]
Orbital MALT Lymphoma: A Case Report
[254,0 KB]
From [cogprints.org] Last viewed: 07.09.2006
Published Quarterly
Mangalore, S outh I ndia
I SS N 0972-5997
Volume 3; I ssue 2; April - June 2004
Case Report
Orbital MALT Lymphoma : A Case Report
Shobha G Pai, MS, DOMS, Associate Professor*
Sumana J Kamath, MS, Associate Professor*
Manjunath M Kamath, MS, DOMS, Associate Professor*
Aarthi R Rau, MD, Assistant Professor,**
Jay Kumar Chhablani, MBBS, Postgraduate Student*
*Dept. of Ophthalmology, Kasturba Medical College Hospital, Attavar, MANGALORE
**Dept. of Pathology, Kasturba Medical College, MANGALORE
Address for Correspondence:
Dr. Shobha G Pai, MS, DOMS,
Associate Professor, Dept. of Ophthalmology,
Kasturba Medical College Hospital, Attavar,
MANGALORE, INDIA. Pin: 575001
E-mail: drsgpai@rediff.com
Citation: Pai SG, Kamath SJ, Kamath MM, Rau AR, Chhablani JK. Orbital MALT
Lymphoma : A Case Report. Online J Health Allied ...
[130]
A potential survival strategy for human follicular lymphoma cells
[315,7 KB]
From [www.bioch.ox.ac.uk] Last viewed: 07.09.2006
1. The Glycobiology Institute, Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, U.K. 2. Molecular Immunology Group, Tenovus Laboratory, Cancer Sciences Division, Southampton University Hospitals
Trust, Southampton SO16 6YD, UK. 3. Clinical Universitaria de Navarra, University of Navarra, 31003, Pamplona, Spain.
A potential survival strategy for human follicular lymphoma cells
involving oligomannose glycans in the antigen binding site of IgG
Radcliffe, C.M.
1
, Arnold, J.N.
1
, Suter, D.M.
1
, Wormald, M.R.
1
, Harvey, D.J.
1
, Bendandi, M.
3
, Dwek, R.A.
1
, Stevenson, F.K.
2
Rudd, P.M.
1
INTRODUCTION : FL cells express a strikingly high incidence of glycosylation sites in the variable regions of their
surface immunoglobulins (Igs), a feature ...
[131]
H:\JLP\lymphoma errata.wpd
[72,8 KB]
From [www.facs.org] Last viewed: 07.09.2006
About Non-Hodgkin’s Lymphoma
About 54,370 new cases of non-Hodgkin lymphoma (NHL) will occur this year in the United States.
Lymphomas are cancers that begin by the malignant transformation of a lymphocyte in the lymphatic
system. The prefix "lymph" indicates their origin in the malignant change of a lymphocyte and the suffix
"oma" is derived from the Greek word meaning "tumor".
Lymphomas, including Hodgkin lymphoma , result from an acquired injury to the DNA of a lymphocyte.
Scientists know that the damage to the DNA occurs after birth and, therefore, is acquired rather than
inherited. The change or mutation of DNA in one lymphocyte produces a malignant transformation. This
mutation results in the uncontrolled and excessive growth of the lymphocyte, and confers a survival
advantage on the malignant lymphocyte and the cells that are formed from its multiplication. The
accumulation of these dividing cells results in ...
[132]
Diffuse Large B-Cell Lymphoma
[1014,4 KB]
From [utm-ext01a.mdacc.tmc.edu] Last viewed: 07.09.2006
MDACC
Diffuse Large B-Cell Lymphoma
a
(Page 1 of 5)
(V1; 8/8/03)
No
No
Note: If available, clinical trials should be considered
as preferred treatment options for eligible patients.
Yes
Yes
No
Yes
Low Risk
High Risk
PATHOLOGIC
DIAGNOSIS
INITIAL
EVALUATION
Hematopathology review of all slides with at
least one paraffin block representative of the
tumor. Rebiopsy if consult material is
nondiagnostic.
Adequate immunophenotyping to establish diagnosis
b
> Paraffin panel: CD45 (LCA),CD20 (26/Pan B),
CD3;(optional - cytokeratin)
or
> Cell surface marker analysis by flow cytometry:
kappa/lambda, CD45, CD3, CD5, CD19, CD10,
TdT, CD14, CD13, CD33, CD20
Additional immunohistochemical studies to
establish lymphoma subtype
> ...
[133]
Non-Gastric MALT Lymphoma
[286,9 KB]
From [utm-ext01a.mdacc.tmc.edu] Last viewed: 07.09.2006
(Page 1 of 1)
CLINICAL
STAGE
LOCAL TREATMENT
(V1; 9/26/03)
No
No
Note: If available, clinical trials should be considered
as preferred treatment options for eligible patients.
Yes
Yes
No
Yes
Low Risk
High Risk
Non-Gastric MALT
a
Lymphoma
Stage IE - II
Clinical Trial
or
Locoregional Radiotherapy with or without Rituxan
Surgery for certain sites (lung, breast [with or
without Radiotherapy], skin
c
, thyroid,
colon/small bowel)
Stage III - IV
low grade
Stage IE - IV,
MALT
a
lymphomas
coexistent with large cell
lymphoma
b
Treat per Diffuse Large B-Cell
Lymphoma Guidelines (Page 1)
a
MALT = mucosal - associated lymphoid tissue.
b
DLBCL coexistent with MALT cell lymphoma is ...
[134]
Hodgkin's Lymphoma
[1890,8 KB]
From [utm-ext01a.mdacc.tmc.edu] Last viewed: 07.09.2006
Hodgkin's Lymphoma
(Page 1 of 11)
(Draft 2 5/22/03)
Draft 3 6/3/03
DRAFT 8/5/03
D evelopment
C redits
DIAGNOSIS
WORKUP
History and physical including:
-B symptoms
-ETOH intolerance
-Pruritus
-Fatigue
-Performance status
-Exam of nodes
-Spleen, liver
CBC, differential, platelets
LDH, Liver Function Tests including
Alkaline phosphatase, SGOT, SGPT, and
albumin, BUN, creatinine
Beta-2-microglobulin
HIV 1 and HIV 2
Chest X-ray
CT Neck, chest, abdomen and pelvis
PET or gallium scan especially if equivocal CT
Bilateral bone marrow biopsies
Pulmonary function studies if clinically indicated
MUGA or echocardiogram
Counseling: Fertility, psychosocial if clinically
indicated
FNA alone is generally
insufficient
Core needle biopsy
may be adequate if
diagnostic, but
recommend ...
[135]
LYMPHOMA
[88,8 KB]
From [www.catie.ca] Last viewed: 07.09.2006
CATIE Fact SHEET
Lymphoma , page 1 of 3
Fact SHEET
LYMPHOMA
What is lymphoma ?
Lymphoma is a term used to described several
different cancers that can affect the lymphatic
system. In HIV-positive people, lymphoma is
linked to immune deficiency. The risk of
developing lymphoma seems to increase as the
immune system weakens. There are two general
types of lymphomas: Hodgkin’s disease and
non-Hodgkin’s lymphoma (NHL). Although both
types can affect people living with HIV, NHL is
classified as an AIDS-defining illness.
Lymphoma originates in a type of white blood
cell called a B-cell. These cells may start to
grow rapidly and develop into tumours that can
spread in the lymphatic system. The lymphatic
system is made up of vessels that branch out
into all parts of the body. These vessels carry
lymph, a clear, watery fluid that contains the ...
[136]
MEET THE EXPERT ON NON-HODGKIN LYMPHOMA:
[56,8 KB]
From [www.cancereducation.com] Last viewed: 07.09.2006
1
MEET THE EXPERT ON NON-HODGKIN LYMPHOMA :
N
EW
I
NSIGHTS AND
T
REATMENTS
LLS 04-05 Sullivan
6/10/04
MR. SULLIVAN:
My name is Larry Sullivan. I was diagnosed with non-Hodgkin lymphoma
approximately 3 years ago. It was discovered by myself while shaving. I felt
a lump, went to the doctor, had a fine-needle biopsy, CAT scans, and it was
identified as indolent non-Hodgkin lymphoma . The treatment options presented
to me at the time were to do nothing, just watch and wait, or to actively pursue
the disease. I chose with my doctor to pursue it, and the options that were made
available to me were radiation or Rituxan
®
(Rituximab), which was emphasized,
and that is the one that we chose.
At that time, I had two enlarged lymph nodes that were identified, and both of
them were removed and proved to be non-Hodgkin ...
[137]
Expression ofMAdCAM-1andPNAdin Inflamma toryand MALT Lymphoma ...
[757,2 KB]
From [www.jsltr.org] Last viewed: 07.09.2006
Expression ofMAdCAM-1andPNAdin Inflamma
toryand MALT Lymphoma Tissues of Ocular
Adnexa, Thyroid, SalivaryGland and Lung
-
Yi-XuanLiu,NobuyaOhara,TadashiYoshino,Gui-ShanJinandTadaatsuAkagi
Mucosa-associatedlymphoidtissue(MALT)lymphomasusuallyarisefromacquiredMALT induced
bychronic inflammation or autoimmuneprocesses. In MALT ofthegastrointestinal tract lymphocyte
homing mechanisms operate primarily through interactions between integrin, expressed on mucosal
lymphocytes, and MAdCAM-1, expressed on endothelium of high endothelial venules (HEV). In the
present study,theexpression ofMAdCAM-1andperipherallymphnodevascularaddressin(PNAd)was
examined immunohistochemicallyin normal,inflamed and MALT lymphoma tissues ofvarious organs.
It was shown that MAdCAM-1was expressed on HEV in thegastrointestinaltract and thyroid that are
inflamed or affected with MALT lymphomas,but not in theocularadnexa,lung,and salivarygland. ...
[138]
Sara Kaiser Biochem 118 June 1, 2004 Non-Hodgkin’s Lymphoma
[67,0 KB]
From [biochem118.stanford.edu] Last viewed: 07.09.2006
Sara Kaiser
Biochem 118
June 1, 2004
Non-Hodgkin’s Lymphoma
Non-Hodgkin’s Lymphoma is currently the fifth most common cancer in the
United States. For reasons as yet undetermined by scientists, it has become increasingly
more common over the last several decades. Fortunately, the future of Non-Hodgkin’s
Lymphoma looks to be promising, as research for new treatments has proved fruitful in
the last decade.
Lymphoma refers to cancer of the lymphatic system, and is broken up into two
types: Hodgkin’s and Non-Hodgkin’s. Hodgkin’s disease is identified by “specific cells
- Reed-Sternberg cells - that are not found in any other cancerous lymphomas or cancers”
(NHL
1
)Both of these diseases involve a mutation among B lymphocytes – a type of white
blood cell - which causes them to divide much more rapidly than normal cells.
Unfortunately, it is not currently known what causes this mutation, ...
[139]
Remission of lymphoma after drug withdrawal in rheumatoid arthritis
[1080,1 KB]
From [www.mja.com.au] Last viewed: 07.09.2006
500
MJA
Vol 177
4 November 2002
NOTABLE CASES
The Medical Journal of Australia ISSN: 0025-729X 4 November
2002 177 9 500-501
©The Medical Journal of Australia 2002 www.mja.com.au
Notable Cases
A 63-year-old man with rheumatoid arthritis presented with pain and swelling of his right buttock.
Imaging and tissue biopsy revealed a diffuse large B-cell, non-Hodgkin’s lymphoma . The disease-
modifying drugs he was taking, cyclosporin and methotrexate, were stopped, and the lymphoma
resolved spontaneously without the use of chemotherapy.
(MJA 2002; 177: 500-507)
R
HEUMATOID ARTHRITIS
is a common disorder. Its various
articular and extra-articular manifestations are well
described, but less well known is the association between
rheumatoid arthritis and malignancy. There is an intrinsic
risk of lymphoma , particularly non-Hodgkin’s lymphoma ...
[140]
LYMPHOMA OF SPINE PRESENTING AS POTT’S DISEASE : A CASE REPORT ...
[207,6 KB]
From [medind.nic.in] Last viewed: 07.09.2006
Case Report
Ind. J. Tub. 2000, 47, 107
LYMPHOMA OF SPINE PRESENTING AS POTT’S
DISEASE : A CASE REPORT
Veena Maheshwari
1
, Kiran Alam
2
, Shah Aiam Khan
3
*, Ghazala Mehdi
2
and A.A. Iraqi
4
*
(Original version received on 16.9.99; Revised version received on 15.1.2000; Accepted on 29.2.2000)
Summary: A rare case of primary non-Hodgkin’s lymphoma of spine in a 40 year old female, initially diagnosed and treated
as Pott’s disease is presented.
INTRODUCTION
Lymphomas and leukemias rarely involve the
vertebral column. The clinical manifestations of
lymphoma can closely mimic tuberculous
spondylitis
1
. Lymphoma of bone is usually
secondary to lymphoma of lymphoid tissue.
CASE REPORT
A 40 year old female presented with pain ...
[141]
Intra-Arterial Chemotherapy for CNS Lymphoma
[56,7 KB]
From [www.radiology.osu.edu] Last viewed: 07.09.2006
Intra-Arterial Chemotherapy
for CNS Lymphoma
Intra-Arterial Chemotherapy Treatment Schedule:
• Intra-arterial chemotherapy requires a hospital stay for 2 nights after the first treatment.
You will be discharged on the 3 day between 9:00 and 10:00 in the morning. You will be
rd
discharged the 2 day after subsequent treatments are completed.
nd
• You will be scheduled for admission to the hospital every 4-5 weeks. After every 2 cycles
of chemotherapy, a MRI will be done to see how effective the treatment was on the tumor.
Dr. Newton will go over the MRI scans with you. If your MRI is done at another facility,
please bring to your doctor’s appointment the old and new scan for comparison. If your
MRI is done at OSU, please bring all the films with you to see Dr. Newton. The MRI
department should send them with you.
• On the day of admission, please report to The James Cancer ...
[142]
Primary Calcified T-Cell Lymphoma of the Urinary Bladder: A Case ...
[3490,9 KB]
From [www.kjronline.org] Last viewed: 07.09.2006
252
Korean J Radiol 4(4), December 2003
Primary Calcified T-Cell Lymphoma of
the Urinary Bladder: A Case Report
Primary malignant lymphoma of the urinary bladder is extremely rare, and to
our knowledge, no case described in the radiologic literature has been accompa-
nied by calcification. We report a case in which the condition was associated with
calcification, and describe the pelvic CT and MR imaging findings.
rimary lymphoma of the urinary bladder accounts for less than 1% of the
neoplasms occurring in this organ. A few cases have been reported in the
radiology literatures (1 3), but in no instance has been described associ-
ated calcification. We report the CT and MR imaging findings in a patient with urinary
bladder lymphoma involving internal calcification.
CASE REPORT
A 30-year-old woman presented with a two-month history of gross hematuria and
dysuria. ...
[143]
LYMPHOMA
[366,4 KB]
From [meds.queensu.ca] Last viewed: 07.09.2006
Lymphoma - page 1
LYMPHOMA
Lecture date
2004 Mar 31
Course
Meds 412 - Phase 2A
Lecturer
Dr. David Lee
Notes updated
2004 Feb 28
W
HAT ARE LYMPHOMAS
?
Lymphomas are B- and T-cell neoplasms that typically result in the
enlargement of lymph nodes; however, the spleen, bone marrow and
other tissues may also be infiltrated.
L
YMPH OMA VS
L
EUKEMIA
In general, those neoplasms which predominantly affect lymph nodes or
tissues are referred to as lymphomas, and those affecting the bone
marrow with circulating neoplastic cells in the blood as leukemias.
This distinction is both fuzzy and somewhat artificial because any
lymphoid neoplasm can have both solid and circulating components to
them.
C
ONCEPTUALIZING LYMPHOID NEOPLASMS AS EXPANSIONS OF
DEVELOPMENTAL STAGES IN LYM PHOPOIESIS ...
[144]
Lymphoma Today
[30,1 KB]
From [www.lymphoma.org] Last viewed: 07.09.2006
SPRING 2004
VOLUME 3 NUMBER 1
Lymphoma Today
LRF Announces $1,065,000 in
New Research Awards
Passing The Torch of LRF Leadership
The highest priority of the research program of the Lymphoma Research Foundation (LRF)
is to support and encourage the efforts of top fellows and scientists at the nation’s lead-
ing academic institutions to expand their research efforts and accelerate the process of
developing successful treatments and ultimately a cure for lymphoma .
John M. Pagel, MD, PhD; of the Fred Hutchinson Cancer Research
Center in Seattle, WA will receive $ 225,000 in total for his project titled
Pretargeted Radioimmunotherapy for CD20+ Non-Hodgkin’s Lymphoma .
The overall objective of this project is to improve the efficacy and decrease
the toxicity of radioimmunotherapy for patients with relapsed non-
Hodgkin’s lymphomas by dramatically improving the ratio of radiation
...
[145]
Leukemia, Lymphoma, and Myeloma Leukemia, Lymphoma, and Myeloma
[235,7 KB]
From [www.sylvester.org] Last viewed: 07.09.2006
.
Your Treatment Team
Your Treatment Team
LEADING
THE SEARCH
FOR A
CANCER CURE
Sylvester Comprehensive Cancer Center
1475 NW 12th Avenue • Miami, Florida 33136
305-243-1000
1-800-545-2292
www.sylvester.org
An Equal Opportunity/Affirmative Action University
.
Leukemia,
Lymphoma ,
and Myeloma
UM/Sylvester’s leukemia, lymphoma , and
myeloma treatment team includes highly
trained hematologist/oncologists and radiation
oncologists, all widely recognized for their work
in the field. The team is supported by a group
of basic science and clinical researchers who
work diligently to learn more about these
diseases—their detection and treatment, as
well as options to improve each patient’s
quality of life.
As is true with all cancer specialties at
UM/Sylvester, the blood-related ...
[146]
The growth of cutaneousT-cell lymphoma is stimulated by immature ...
[524,7 KB]
From [www.transimmune.net] Last viewed: 07.09.2006
IMMUNOBIOLOGY
The growth of cutaneousT-cell lymphoma is stimulated
by immature dendritic cells
Carole L. Berger, Douglas Hanlon, Daniel Kanada, Madhav Dhodapkar, Vivian Lombillo, Nianci Wang, Inger Christensen,
Gregory Howe, Jill Crouch, Paul El-Fishawy, and Richard Edelson
In the initial stage of cutaneous T-cell
lymphoma (CTCL), proliferating CTCL
cells are concentrated in the epidermis in
close association with an immature den-
dritic cell (DC), the Langerhans cell. Be-
cause long-term in vitro culture of CTCL
cells has proven difficult, the in vivo
association with the major antigen-pre-
senting cell (APC) of the epidermis has
been postulated to play a role in directly
stimulating the clonal T-cell proliferation.
We report that CTCL cells can be repro-
ducibly grown in culture for 3 months
when cocultured with immature DCs.
CTCLcells retain ...
[147]
WHAT’S LYMPHOMA?
[674,6 KB]
From [www.lymphomation.org] Last viewed: 07.09.2006
Patients Against Lymphoma
Patients helping Patients
1305 Mason Avenue
Staten Island, NY 10306
Phone: 718-980-0635 | Fax: 801-409-5736
KarlS@Lymphomation.org
www.Lymphomation.org
W
e are guided by our scientific advisors,
the peer-reviewed literature, medical
professionals fighting lymphoma , and
patient questions .
We continuously improve our
website in response to
visitor questions and patient needs .
by linking you directly to reputable
sources of information,
such as ClinicalTrials.gov.
Visit us at
www.Lymphomation.org
What’s Lymphoma ?
L
ymphoma is a cancer that affects blood
cells called lymphocytes – immune cells that
normally protect you from illness.
Damage to genes in these cells can sometimes
lead to abnormal cell behavior which makes ...
[148]
LEUKEMIA and LYMPHOMA TESTS
[193,5 KB]
From [www.bumc.bu.edu] Last viewed: 07.09.2006
LEUKEMIA and LYMPHOMA TESTS
FOR LAB USE ONLY:
Date Received:
Center For Human Genetics, Inc.
Sample Type:_
Boston University School of Medicine
Time: _
700 Albany Street, Suite 408, Boston, MA 02118-2394
Lab No.: __
Director: Aubrey Milunsky, M.D., D.Sc.
Telephone: (617) 638-7083, Fax: (617) 638-7092
PATIENT:
NAME:
Male
DOB:
ADDRESS:
PHONE:(day)
Female
(eve)
PHYSICIAN:
NAME:
PHONE:
ADDRESS:
FAX:
E-MAIL:
(Check all that Apply)
Disease
Probe
Location or rearrangement
CML: bcr-M (major) breakpoint
bcr/abl
t(9;22)(q34;q11.2)
CM and ALL, bcr-M and bcr-m (minor) break-points
bcr/abl-ES
t(9;22)(q34;q11.2)
M3 AML and M3 AML variant
PML/RARA
t(15;17)(q22;q21)
M2 AML
AML1/ETO
t(8;21)(q22;q22)
M4 and M4Eo AML, Rarely in M2 or M5 AML
...
[149]
Unusual caseof cutaneous T-cell lymphoma with a prominent ...
[812,5 KB]
From [www.jsltr.org] Last viewed: 07.09.2006
Unusual caseof cutaneous T-cell
lymphoma with a prominent
reactivepopulation of B lymphocytes
Yoshihiro Nozawa ,Kazuhiro Tasaki ,Mikio Ohtsuka ,Keiji Iwatuki ,
Kunihiko Tominaga and Masafumi Abe
Department ofPathology
Department ofDermatology,School ofMedicine,Fukushima Medical University,Fukushima,Japan.
Surgical PathologyDivision,Takeda General Hospital,Aizuwakamatu,Japan
A 58-year-old Japanese woman presented an eruption in the region of the back and the upper
extremities, a subcutaneous nodule on the right breast, and a left cervical lymphadenopathy. The
excision biopsy specimens, of a subcutaneous nodule and a lymph node, showed a vaguely nodular
growth pattern comprising a smallCD20 IgD lymphocyteinfiltratearoundclustersofmedium-sizedor
largeCD3 lymphoid cells,in which histologicaldistinction between malignant lymphoma and reactive
lymphoidhyperplasiawasdifficult. Southern-blotanalysisrev...
[150]
Spectrum of Malignant Lymphoma in Sarawak General Hospital
[230,7 KB]
From [www.jsltr.org] Last viewed: 07.09.2006
Spectrum of Malignant Lymphoma
in Sarawak General Hospital
Suat-Cheng Peh ,HenryR Gudum ,Yan-Chin Tai ,
Fei-Ling Wong and Jamil Dolkadir
Departments ofPathology,UniversityofMalaya,Kuala Lumpur
UniversityofMalaysia,Sarawak
Departments ofPathology,UniversityofMalaya,Kuala Lumpur
Departments ofPathology,UniversityofMalaya,Kuala Lumpur
Sarawak General Hospital,Kuching,Malaysia
Recent epidemiological studies reported changing trend of lymphoid neoplasia in the past few
decades. Previous studyoflymphomas from East Malaysia from 1981to 1983showed a pattern similar
to other Asian countries,except for low incidence ofperipheral T-cell lymphoma in Sarawak.Current
studyanalyzed materialsfrom 1996to 1998,with theaim to elucidatepossiblechangeindiseasepattern,
ifany,inSarawak 15yearslater. A totalof70re-confirmedlymphomacaseswereclassifiedusing WHO
proposedlistoflymphoidneoplasms. Therewere61(87.1%)non...