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LifePro Financial Services Inc. 225 West Plaza – Solana Beach, CA 92075 – PH: 888-543-3776 – FAX: 619-793-5990 – Email: greg@lifeproinc.com Cancer – Lymphoma Proposed Insured Name: M F Date of Birth or Age Face Amount: __ Max. Premium; $__/yr. UL WL Term Survivorship Do you currently smoke cigarettes? Y N If no, did you ever smoke: Never Quit (Date): Do you currently use any other tobacco products (i.e. nicotine patches, cigars, pipe, chew): Y N If yes, please provide details: When did you last use any form of tobacco:__(Month) __(Year) Type used last: Agent: _ Agent Phone: __ LifePro Finacial Services, Inc. – Phone: 888-543-3776 – FAX: 619-793-5999 – email: greg@lifeproinc.com (1) Exact classification of the malignant lymphoma : Modern Classification Terminology: Small lymphocytic (SL) Follicular small cleaved cell (FSC) Follicular, mixed, small cleaved ...

Cancer – Hodgkin’s Lymphoma LifePro Financial Services Inc. 225 West Plaza – Solana Beach, CA 92075 – PH: 888-543-3776 – FAX: 619-793-5990 – Email: greg@lifeproinc.com Proposed Insured Name: M F Date of Birth or Age Face Amount: __ Max. Premium; $__/yr. UL WL Term Survivorship Do you currently smoke cigarettes? Y N If no, did you ever smoke: Never Quit (Date): Do you currently use any other tobacco products (i.e. nicotine patches, cigars, pipe, chew): Y N If yes, please provide details: When did you last use any form of tobacco:__(Month) __(Year) Type used last: Agent: Agent Phone: LifePro Finacial Services, Inc. – Phone: 888-543-3776 – FAX: 619-793-5999 – email: greg@lifeproinc.com (1) Type of Hodgkin’s Lymphoma : Lymphocyte predominance Nodular sclerosis Mixed Cellularity Lymphocyte depletion Other: __ (2) Date of initial diagnosis: __ Date of last treatment: __ ...

Last Dance – Malignant Lymphoma in Ferrets Bruce H. Williams, DVM Diplomate, American College of Veterinary Pathologists Email: williamsb@afip.osd.mil Lymphoma – a swift silent killer. One day your ferret appears happy and healthy; the next day you notice a small hard lump under the jaw or by the leg. After a quick trip to the vet, you learn the sad truth – your beloved friend will soon be a cherished memory. In this third article on neoplasia in ferrets, let’s look at lymphoma - what it is, how it progresses so quickly, and why the results are so often tragic. Lymphoma is a neoplasm , an abnormal proliferation of cells beyond the body’s normal control mechanisms. In this case, lymphocytes, the cells which populate lymph nodes and control and execute many functions of the body’s immune system are the cells whose proliferation ...

MALT Lymphoma By Titaree Suwannalai Advisor Kanjana Shotelersuk Page 2 Background ? MALT lymphoma --> lymphoma arising from mucosa-associated lymphoid tissue ? 8% of all NHL ? Recently re-classified as “ Extranodal marginal zone lymphoma of MALT type “ ? Marginal zone lymphoma ( MZL ) in WHO/ REAL classicifications --> encompassed 3 closedly related lymphoma – Nodal Page 3 Clinical Features – Primary splenic – Extranodal lymphoma of MALT type ? Composed of mature B cell , lacking expression of CD5 and CD 10 ? Overlapping morphologic features, but distinct clinical behaviors ? Cytogenetic/ molecular genetic --> distinctiveness ...

lymphoma What is the current role of Allogeneic Stem Cell Transplantation in Lymphoma ? What is the current role of Allogeneic Stem Cell Transplantation in Lymphoma ? UNDEFINED Theoretical Justification for Allogeneic Transplantation Tumor free graft Undamaged Stem Cells Avoidance of MDS/secondary AML Graft versus lymphoma effect Problems with Allogeneic Transplantation in Lymphoma Lack of suitable donors High Treatment Related Mortality Regimen related toxicity Infection GVHD Increased Costs NHL and Transplant Relapsed diffuse large B-cell Relapsed follicular center (low grade) Newly diagnosed and relapsed mantle cell Newly diagnosed and relapsed peripheral T-cell NHL Standard treatment ...

Lymphoma 17 17.1. INTRODUCTION AND SUMMARY Table 17.1. Summary of incidence and mortality statistics: lymphoma INCIDENT CASES DEATHS males females both sexes males females both sexes All cancers (invasive, in situ and uncertain) (ICD-O-2 C00 to C80, M-9590 to M-9723) 1997 cases 265 232 497 117 101 218 % of all cancers 2.5% 2.1% 2.3% 2.9% 2.9% 2.9% Incidence and mortality rates (per 100,000 persons per year) crude rate 14.6 12.6 13.6 6.5 5.5 6.0 World age-standardised rate 12.5 9.6 5.1 3.6 European age-standardised rate 16.5 12.5 7.3 5.2 cumulative risk (0-74) 1.3% 1.0% 0.6% 0.4% mortality/incidence ratio 0.442 0.435 0.439 Time trends (all cancers) 1994 cases ...

lymphoma Cutaneous T-Cell Lymphoma Shachar Peles M.D. Hematology & Oncology Grand Rounds September 26, 2003 Case Presentation 52 year old Left forearm rash for 4 years Intermittent erythematous patches Left forearm rash flared up – nodular, rapidly progressing Case Presentation PMH: Polio – age 4 Cyst removal near parotid 30 yrs ago Meds: Centrum Silver, Gingko All: NKDA SH: 1ppd x 25 years. Social Etoh. FH: F – died age 92 – CHF M – Alzheimer’s ...

lymphoma Primary CNS Lymphoma Geoffrey L. Uy Case Presentation A 47 y/o WF who presented to BJH with a 1 ½ year history of visual problems. She complained of flashing lights and headaches for several days at a time and was initially diagnosed with migraines. Despite close follow-up with multiple specialists, her vision problems progressed over this time. In addition to flashing lights, she c/o floaters and blurred vision. She was eventually diagnosed with AZOOR (acute zonal occult outer retinopathy). In May 2003, she developed left sided weakness along with gait instability. CSF revealed 13 RBC, 1 RBC, glucose 73, protein 33, no malignant cells Primary ...

A Project of the New Mexico AIDS Education and Training Center. Partially funded by the National Library of Medicine and the New Mexico Department of Health Fact Sheets can be downloaded from the Internet at http://www.aidsinfonet.org New Mexico AIDS InfoNet www.aidsinfonet.org Fact Sheet Number 512 LYMPHOMA WHAT IS LYMPHOMA ? Lymphoma is a cancer of white blood cells called B-lymphocytes. They multiply rapidly and form tumors. Lymphoma of the brain or spinal cord is called central nervous system (CNS) lymphoma . AIDS-related lymphoma is sometimes called Non-Hodgkin’s Lymphoma (NHL). Hodgkin’s Disease, another type of lymphoma , is rare in people with HIV. In 1985, the Centers for Disease Control added NHL to the list of diseases that define AIDS. The longer you live with a ...

Neurological Signs due to Spinal Lymphoma in a Ferret Jennifer M. Mateleska, DVM and Joerg Mayer, Dr. Med.vet., MSc. Lymphoma is one of the most common neoplasias seen in ferrets and can affect ferrets of all ages. The disease can involve numerous tissues, most often including peripheral and visceral lymph nodes, liver, spleen, bone marrow, kidney, lung, mediastinum, and intestine. Less often, the nervous system, stomach, pancreas, adrenal glands, and skin are involved. Clinical signs of lymphoma in ferrets are often vague and can mimic those seen in other diseases. Viral involvement has been suggested, but there is no significant evidence of this to date. Presentation A six-year-old castrated male ferret named Fred presented to the Exotics Service at Tufts University School of Veterinary Medicine with a three-day history of lethargy and hind limb paresis. There was no known history ...

Survey and Audit of HIV- Related Lymphoma in North Thames Dr Gary Brook On behalf of the N Thames HIV/GUM Audit & Education Committee Page 2 Method • Survey and Audit Forms were mailed to 26 HIV Care-Provider Units in North Thames in April 2003 • The Survey looked at lymphoma management policies for the units • The Audit asked for information on all lymphoma cases in the last two years to a maximum of 10 Page 3 Results: Survey • 10/26 units participated: 38.5% • Reasons given for non-participation included: – difficulties in identifying the cases due to lack of specific clinic codes – Lack of feedback from oncology units – Lack of time, especially in the light of two recent BHIVA national audits Page ...

SPECIAL SERIES ARTICLE FINE NEEDLE ASPIRATION; DIAGNOSIS OF NODAL HODGKIN’S LYMPHOMA (PART II) A.R. Khan; Shuab Omer; Sumia Rashid; Syed Besina Abstract: 6620 lymph nodes were aspirated over 11 yr. period (Jan. 1991 - Dec. 2001) yielding 345 lymphomas. This included 90 cases of HL (26%). Out of these only 76 cases (84.4%) were diagnosed by FNA irrespective of sub typing. A suspicion of disease arose in 6 cases (6.7%). Smears were negative with picture of reactive lymphadenitis in another 8 cases (8.9%). This was attributed to scanty material in the aspirates. Subtyping attempted showed a correlation with histology in 50 cases (>55%). The cytohistopathologic correlation was best seen in lymphocyte predominant and mixed cellularity subtypes. Diagnosis and sub typing of NSHL was more difficult. There was only one case of lymphocyte depletion reticular disease correctly diagnosed on FNA. Most ...

Lymphoma Discrimination by Computerized Triple Matrix Analysis of List Mode Data from Three-Color Flow Cytometric Immunophenotypes of Bone Marrow Aspirates R. Bartsch, 1 M. Arland, 2 St. Lange, 2 Ch. Kahl, 1 G. Valet, 3 and H.-G. Ho ¨ffkes 2 * 1 Division of Hematology/Oncology, Department of Medicine, Otto-von-Guericke-University of Magdeburg, Germany 2 Klinikum Fulda, Medizinische Klinik III, Fulda, Germany 3 Max-Planck-Institute of Biochemistry, Martinsried, Germany Received 19 November 1999; Revision Received 16 May 2000; Accepted 17 May 2000 Background: The goal of this study was to evaluate a self-learning algorithm for the computer classification of information extracted from flow cytometric immunophe- notype list mode ...

Strategic Plan For Addressing the Recommendations of the Leukemia, Lymphoma , and Myeloma Progress Review Group LLM-PRG Strategic Plan October 2002 1 Page 2 Message From the Director October 2002 In 2001, hematologic cancers-- as a group the fourth most common cancer -- claimed the lives of 60,300 Americans, drained the financial and emotional resources of hundreds of thousands, and continued to resist our best efforts to find a cure. Despite these tragic consequences, we are nevertheless increasing our scientific knowledge of this group of blood-related cancers and are using that knowledge to help reduce the burden. This year the death toll from hematologic cancers is expected to be 58,300 Americans. Continued scientific inquiry will yield unprecedented amounts of vital information essential to eliminating these diseases. ...

lymphoma Lymphoblastic Lymphoma By Mohamed Bayoumy, M.D. Epidemiology Lymphoma (Hodgkin’s and non-Hodgkin’s) is the third most common childhood malignancy. Non-Hodgkin’s lymphoma (NHL) accounts for approximately 7% of cancers in children less than 20 years of age. In the United States, there are about 800 new cases of NHL diagnosed each year. Incidence is approximately 10 per 1,000,000. Epidemiology Although there is no sharp age peak, occurs most commonly in the second decade of life, and occurs less frequently in children less than 3 years of age. NHL is the most frequent malignancy in children with AIDS, and it often occurs before the age of 4 years in those who have vertical transmission of the virus. Screening for HIV should be considered for all children with NHL. Prognosis More than 70% of ...

ABOUT US Patients Against Lymphoma is a not-for- profit organization founded in July of 2002 with the help and encouragement of many individuals – all directly affected by lymphoma . Better therapies are needed urgently to improve the survival and quality of life of patients living with lymphomas. Presently, ~27,200 die of lymphoma each year in the United States , and many forms of lymphoma are incurable with the harsh chemo- and radio- therapies that are often given repeatedly with diminishing benefit. Lymphoma is a cancer that affects blood cells called lymphocytes , immune cells that protect you from viruses and bacteria, and even cancer. Damage to these cells can sometimes lead to abnormal cell behavior preventing the cells from dying when they should, or causing sustained rapid cell division. These malignant ...

Immunobiology of Cutaneous T Cell Lymphoma ( Berger, Cresswell, Edelson, Girardi, Glusac, Hanlon, Heald) For the past 17 years Richard Edelson, Chairman of the Department of Dermatology, has coordinated a broad based research program directed at the elucidation of the basic and clinically relevant properties of cutaneous T cell lymphoma (CTCL) cells. This program now has several interrelated components, integrating the contributions of investigators both inside and outside of Dermatology. The uniquely large referred CTCL patient base at Yale has facilitated a substantial number of clinical trials aimed at finding better treatments both for patients with "early" as well as with advanced disease. Richard Edelson, M.D. and Carole Berger, Ph.D. (Dermatology) have collaborated for over twenty years on studies of the biologic features of CTCL cells. Substantial progress has been made in identifying tumor specific ...

a report by M V a n G l a b b e k e and I T e o d o r o v i c EORTC Data Center, Brussels I n t r o d u c t i o n For the last 30 years, the European Organisation for Research and Treatment of Cancer (EORTC) Lymphoma Group has successfully faced the challenge of conducting large international randomised trials in aggressive as well as indolent subtypes of non-Hodgkin’s Lymphoma (NHL). The present paper summarizes the achieved results, and the objectives of on-going projects of the group. I n d o l e n t S u b t y p e s For follicular disease, the group has mainly focussed on the evaluation of new agents. In 1985 a randomised trial was started comparing maintenance treatment with interferon-alpha for one year versus no further treatment in patients with stages III or IV low-grade NHL who had reached a response to cyclophosphamide, ...

NH LYMPHOMA BOTH SEXES TABLE 1A. -- Characteristics of persons reported to the Connecticut Tumor Registry with an initial non-Hodgkin's lymphoma , 1935-82+ _ Category Male Female Total _ No. with first primary cancer* 3,539 3,195 6,734 No. who developed a second primary cancer 196 123 319 Average age at diagnosis of first cancer, yr 56 60 58 Average yr of diagnosis of first cancer 1966 1967 1967 Person-yr of follow-up 14,378 12,854 27,231 Average follow-up, yr 4.1 4.0 4.0 Percent given radiotherapy for first cancer 52.0 50.5 51.3 _ + ICD-O morphology codes = 9590-9642,9690-9701,9750. * Number excludes all persons who survived less than 2 mo after the diagnosis of their first primary cancer or who developed a simultaneous cancer during this period. First primary cancers diagnosed only at autopsy or by death certificate are also excluded as are in situ cancers. TABLE 1B. -- Microscopic ...

NH LYMPHOMA BOTH SEXES TABLE 1A. -- Characteristics of persons reported to the Danish Cancer Registry with an initial non-Hodgkin's lymphoma , 1943-80+ _ Category Male Female Total _ No. with first primary cancer* 3,655 2,886 6,541 No. who developed a second primary cancer 105 102 207 Average age at diagnosis of first cancer, yr 57 60 58 Average yr of diagnosis of first cancer 1966 1967 1966 Person-yr of follow-up 12,462 10,443 22,905 Average follow-up, yr 3.4 3.6 3.5 Percent given radiotherapy for first cancer 63 63 63 _ + ICD-7 codes = 200, 202. * Number excludes all persons who survived less than 2 mo after the diagnosis of their first primary cancer or who developed a simultaneous cancer during this period. First primary cancers diagnosed only at autopsy or by death certificate are also excluded as are in situ cancers. TABLE 1B. -- Microscopic confirmation among persons ...

Facts About Lymphoma Page 2 All organs are made up of cells. • Normally, cells grow and die in an orderly way. • If a cell turns into a cancer, the cell multiples and accumulates. This growth causes tumors to form. In lymphoma , cancer develops in the lymphatic system. The lymphatic system: • is the part of the immune system – the body’s defense against infection • runs throughout the whole body. Normal Cells Cancerous Cells Lymphoma is a type of cancer This booklet is designed to provide information in regard to the subject matter covered. It is distributed by The Leukemia & Lymphoma Society with the understanding the Society is not engaged in rendering medical or other professional services. Page 3 -2- Parts ...

ELIGIBILITY FORM FLUDARABINE TREATMENT FOR PATIENTS WITH FOLLICULAR LYMPHOMA AND OTHER LOW GRADE NON-HODGKIN’S LYMPHOMA AND WALDENSTROM’S MACROGLOBULINEMIA (This form should be completed before the first dose is dispensed) 1. PATIENT SURNAME 2. GIVEN NAME _ 3. DATE OF BIRTH __ __ __ __ __ __ Day Month Year 4. HEALTH INSURANCE NUMBER __ 5. CENTRE (Circle correct response) 1 Hamilton 2 Kingston 3 London 4 Ottawa Civic 5 Ottawa General 6 Sudbury 7 Thunder Bay 8 Toronto-Sunnybrook 9 Windsor 10 PMH 11 Other (specify below) Other : __ 6. ATTENDING PHYSICIAN __ If not a Cancer Centre physician, please indicate your phone number __ 7. ELIGIBILITY (Patient must meet criteria a or b) a. The patient has stage III-IV follicular or other ...

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Lymphoma Antibody Beth Ruyak/Host “Hi, I’m Beth Ruyak. Each year hundreds of promising medical drugs and products are developed at research institutes throughout the country, but only a handful ever makes it to your local pharmacy. Now one lymphoma treatment developed at the UC Davis Cancer Center shows a lot of potential --- and in the near future, it may help not only cancer patients but people suffering from autoimmune diseases as well.” THESE MICE MAY HOLD THE KEY TO CANCERAT LEAST A TYPE OF CANCER. THEY’RE AN INTEGRAL PART OF DR. JOSEPH TUSCANO’S RESEARCH LAB AT U-C DAVIS CANCER CENTER. Dr. Joseph Tuscano/Oncologist, UC Davis Cancer Center “We’ll take a human tumor and put it in a mouse, and then treat it with the product to see if the tumor shrinks or not, and if the animals live longer or are cured of their disease.” THE “PRODUCT” THAT DR. TUSCANO IS TALKING ABOUT IS SOMETHING THAT HE AND ...

Radioimmunotherapy Radioimmunotherapy Treatment for Lymphoma Treatment for Lymphoma Page 2 What is Lymphoma ? What is Lymphoma ? Originates in Lymphocytes, either T or B cells Originates in Lymphocytes, either T or B cells type of white blood cell Cancer type of white blood cell Cancer Indolent lymphomas Indolent lymphomas low low - - grade or follicular. grade or follicular. live for 10 years or more live for 10 years or more it is usually not curable. it is usually not curable. Aggressive forms Aggressive forms large cell lymphoma large cell lymphoma cured with current treatment regimens cured with current treatment regimens Page 3 Why is it so devastating? ...

Rev. Inst. Med. trop. S. Paulo 43 (5):283-286, September-October, 2001. (1) Centro de Pesquisa Hospital Evandro Chagas/Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brasil. (2) Hospital Universitário Clementino Fraga Filho/Universidade Federal do Rio de Janeiro, RJ, Brasil. (3) Instituto Nacional do Câncer Correspondence to: Antonio Carlos Francesconi do Valle, Centro de Pesquisa Hospital Evandro Chagas/Fundação Oswaldo Cruz, Av. Brasil 4365, 22045-900 Rio de Janeiro, RJ, Brazil. Tel./ fax: (55-21) 590-9988. e.mail: afvalle@cpqhec.fiocruz.br CASE REPORT ADULT T-CELL LEUKEMIA/ LYMPHOMA ASSOCIATED WITH HTLV-1 INFECTION IN A BRAZILIAN ADOLESCENT Antonio Carlos Francesconi do VALLE(1), Maria Clara Gutierrez GALHARDO(1), Ana Claudia Celestino LEITE(1), Abelardo Queiroz Campos ARAÚJO(1), Tullia CUZZI-MAYA(1), Juan Piñeiro MACEIRA(2) & Jane de Almeida DOBBIN(3) SUMMARY We present the ...

Variation in gene expression patterns in follicular lymphoma and the response to rituximab Sean P. Bohen* †‡ , Olga G. Troyanskaya § , Orly Alter § , Roger Warnke ¶ , David Botstein § , Patrick O. Brown* ‡ , and Ronald Levy † Departments of *Biochemistry, † Medicine, ¶ Pathology, and § Genetics, and ‡ Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305 Contributed by David Botstein, December 24, 2002 Analysis of the patterns of gene expression in follicular lymphomas from 24 patients suggested that two groups of tumors might be distinguished. All patients, whose biopsies were obtained before any treatment, were treated with rituximab, a monoclonal ...

lymphoma February 2003 Total registrations 39709 New registrations 4595 (since EBMT 2002) Total number of centres 510 New centres 35 EBMT Lymphoma Registry February 2003 EBMT Lymphoma Registry Diagnosis Definitions T-Cell lymphoma : Angioimmunoblastic T-cell lymphoma (AILD) Peripheral T-cell lymphoma (all variants) Anaplastic large cell lymphoma (ALCL), T- and null-cell types &nb...