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Secondary central nervous system metastases in children with neuroblastoma I. Astigarraga, MD, PhD * , R. Lejarreta, MD, A. Navajas, MD, PhD, A. Fernandez- Teijeiro, MD, I. Imaz, MD, J.L. Bezanilla, MD Pediatric Oncology Unit, Department of Pediatrics, and Pathology Service, Hospital de Cruces, Baracaldo (Vizcaya), Spain Keywords neuroblastoma; nervous system neoplasms; brain metastases; child Abstract Cerebral and meningeal involvement in patients with primary extracranial neuroblastoma ( NB) is unusual although it is generally present in disseminated disease. The intensification of chemotherapy that has prolonged survival in these children has changed the pattern of relapse presentation, as occurs with isolated central nervous system (CNS) disease. We report 4 patients with secondary CNS metastases. Three infants of 16, 14, and 10 months of age, diagnosed with primary abdominal ...

Secondary central nervous system metastases in children with neuroblastoma I. Astigarraga, MD, PhD * , R. Lejarreta, MD, A. Navajas, MD, PhD, A. Fernandez- Teijeiro, MD, I. Imaz, MD, J.L. Bezanilla, MD Pediatric Oncology Unit, Department of Pediatrics, and Pathology Service, Hospital de Cruces, Baracaldo (Vizcaya), Spain Keywords neuroblastoma ; nervous system neoplasms; brain metastases; child Abstract Cerebral and meningeal involvement in patients with primary extracranial neuroblastoma (NB) is unusual although it is generally present in disseminated disease. The intensification of chemotherapy that has prolonged survival in these children has changed the pattern of relapse presentation, as occurs with isolated central nervous system (CNS) disease. We report 4 patients with secondary CNS metastases. Three infants of 16, 14, and 10 months of age, diagnosed with primary abdominal ...

[CANCER RESEARCH 64, 1675–1686, March 1, 2004] Stromal Matrix Metalloproteinase-9 Regulates the Vascular Architecture in Neuroblastoma by Promoting Pericyte Recruitment Christophe F. Chantrain, 1 Hiroyuki Shimada, 2 Sonata Jodele, 1 Susan Groshen, 3 Wei Ye, 3 David R. Shalinsky, 4 Zena Werb, 5 Lisa M. Coussens, 6 and Yves A. DeClerck 1 Departments of 1 Pediatrics and Biochemistry and Molecular Biology and 2 Pathology, Keck School of Medicine, University of Southern California and The Saban Research Institute, Childrens Hospital Los Angeles, Los Angeles, California; 3 Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, ...

ENDOSCOPIC-ASSISTED CRANIONASAL RESECTION OF OLFACTORY NEUROBLASTOMA Anthony Po-Wing Yuen, FRCS, 1 Yiu Wah Fan, FRCS, 2 Ching Fai Fung, FRCS, 2 Kwan Ngai Hung, FRCS 2 1 Division of Otorhinolaryngology, Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong. E-mail: pwyuen@hkucc.hku.hk 2 Division of Neurosurgery, Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong Accepted 18 January 2005 Published online 2 May 2005 in Wiley InterScience (www.interscience.wiley.com). DOI: 10.1002/hed.20193 Abstract: Background. Cranionasal resection was first de- scribed in 1997 for the surgical resection of olfactory neuro- blastoma. The endoscopic transnasal approach is used in cranionasal resection to replace the more invasive craniofacial resection. ...

Web Immagini Gruppi Directory News altro » Ricerca avanzata Preferenze Cerca nel Web Cerca solo le pagine in Inglese Spiacenti, nessun contenuto associato a questo URL Web La ricerca di - cache:puEA8ECsNFQJ:web.hku.hk:8400/facmed/press/2005-07-21/Cranionasal_Resection_of_Olfactory_Neuroblastoma.pdf allintitle: neuroblastoma filetype:pdf OR filetype:doc OR filetype:ppt OR filetype:xls OR filetype:rtf - non ha prodotto risultati in nessun documento. Suggerimenti: Assicurarsi che tutte le parole siano state digitate correttamente. Provare con parole chiave diverse. Provare con parole chiave più generiche. ...

Gen. Physiol. Biophys. (2004), 23, 231—239 231 Calcium-Dependent Proliferation of NG108-15 Neuroblastoma Cells B. Rouzaire-Dubois and J. M. Dubois Laboratoire de Neurobiologie Cellulaire et Moleculaire, CNRS, 91198 Gif-sur-Yvette Cedex, France Abstract. While there is increasing evidence that Ca 2+ plays an important role in regulating cell proliferation, the precise mechanisms have not been clearly eluci- dated so far. In order to gain insight into how Ca 2+ controls cell division, the rate of proliferation, cell volume, viability and attachment to the culture support were measured in NG108-15 neuroblastoma cells in the presence of various extracellular Ca 2+ concentrations ([Ca 2+ ] o ). Culture medium [Ca 2+ ] o was decreased from 1.8 mmol/l to various values down ...

Negative Regulation of Neuroblastoma Cell Growth by Carbohydrate-dependent Surface Binding of Galectin-1 and Functional Divergence from Galectin-3* Received for publication, June 5, 2001, and in revised form, July 12, 2001 Published, JBC Papers in Press, July 12, 2001, DOI 10.1074/jbc.M105135200 Jürgen Kopitz‡, Carolina von Reitzenstein‡, Sabine André§, Herbert Kaltner§, Johannes Uhl‡, Volker Ehemann ¶ , Michael Cantz‡ , and Hans-Joachim Gabius§ From the ‡ Institut für Pathochemie und Neurochemie and the ¶ Pathologisches Institut, Klinikum der Ruprecht-Karls- Universität, Im Neuenheimer Feld 220, D-69120 Heidelberg, Germany and the § Institut für Physiologische Chemie, Tierärztliche Fakultät, Ludwig-Maximilians-Universität, Veterinärstr. 13, D-80539 München, Germany The cell density-dependent growth inhibition of hu- man SK-N-MC neuroblastoma ...

At the age of three, I was diagnosed with Neuroblastoma (Stage IV). I underwent chemotherapy and full body radiation. Since the cancer, I have acquired some severe problems that I have to deal with. They include a bilateral hearing loss, diabetes, and chronic headaches. My mom is a single mother who takes care of her two children while working three or more jobs at a time and without any help whatsoever. Even when I was sick, she was always there. It’s hard for her to come up with enough money to help feed, clothe, and shelter our family let along pay the everyday bills. We really don’t have anything left over and it has become really tight since I started college last fall. The hardest part about attending college is the fact that I feel guilty taking what little is left over to buy books and I couldn’t even do that! My inspiration to be a nurse practitioner came from a friend of mine who died from a brain tumor ...

American Journal of Epidemiology Copyright © 2001 by the Johns Hopkins University Bloomberg School of Public Health All rights reserved 106 Vol. 154, No. 2 Printed in U.S.A. Parental Occupational Exposures and Neuroblastoma de Roos et al. ORIGINAL CONTRIBUTIONS Parental Occupational Exposures to Chemicals and Incidence of Neuroblastoma in Offspring Anneclaire J. De Roos, 1,6 Andrew F. Olshan, 1 Kay Teschke, 2 Charles Poole, 1 David A. Savitz, 1 Julie Blatt, 3 Melissa L. Bondy, 4 and Brad H. Pollock 5 To evaluate the effects of parental occupational chemical exposures on incidence of neuroblastoma in offspring, the authors conducted a multicenter case-control study, using detailed exposure information that allowed examination of ...

[CANCER RESEARCH 60, 712–721, February 1, 2000] Integrins v 3 and v 5 Are Expressed by Endothelium of High-Risk Neuroblastoma and Their Inhibition Is Associated with Increased Endogenous Ceramide 1 Anat Erdreich-Epstein, Hiroyuki Shimada, Susan Groshen, Ming Liu, Leonid S. Metelitsa, Kwang Sik Kim, Monique F. Stins, Robert C. Seeger, and Donald L. Durden 2 Divisions of Hematology-Oncology [A. E-E., M. L., L. S. M., R. C. S., D. L. D.] and Infectious Diseases [K. S. K., M. F. S.], Neil Bogart Memorial Laboratories, and Departments of Pediatrics and Pathology [H. S.], Children’s Hospital Los Angeles, University of Southern California School of Medicine, Los Angeles, California 90027; and Department of Preventive Medicine [S. G.], University of Southern California School of Medicine and the Children’s Cancer Group, Arcadia, California 91066 ...

Neuroblastoma Incidence in Illinois: 1986-1997 Neuroblastoma is one of the most commonly diagnosed solid tumors in young children. The disease originates from neural cell ectoderm that gives rise in the developing fetus to the sympathetic nervous system, the adrenal medulla, and the adrenergic and cholinergic neuroblasts along the sympathetic chain and cranial ganglia. The annual incidence rate among children under 15 years of age in the United States is nine to 11 cases per million (1). In Illinois, according to data reported to the Illinois State Cancer Registry from 1986 through 1997, the annual incidence rate was 10.5 per million. Neuroblastoma incidence at state and county levels has been reported previously for 1986 through 1994 by the Illinois State Cancer Registry (2). The current study updates the previous report through adding three more recent years of data to the original analysis. During the 12-year period ...

Neuroblastoma Protocol applies to the examination of specimens from patients with neuroblastoma and related neuroblastic tumors. Protocol date: July 2005 No AJCC/UICC staging system Procedures • Cytology (No Accompanying Checklist) • Incisional Biopsy (Needle or Wedge) (No Accompanying Checklist) • Resection Authors Stephen J. Qualman, MD Department of Laboratory Medicine, Children’s Hospital, Columbus, Ohio Jay Bowen, MS Department of Laboratory Medicine, Children’s Hospital, Columbus, Ohio Patrick L. Fitzgibbons, MD Department of Pathology, St. Jude Medical Center, Fullerton, California Susan L. Cohn, MD Department of Pediatrics, Northwestern University, Chicago, Illinois Hiroyuki Shimada, MD, PhD Department of Pathology and Laboratory Medicine, Children’s Hospital Los Angeles, Los Angeles, California For the Members of the ...

Dear Lunch for Life Sponsor, The Children’s Neuroblastoma Cancer Foundation would like to give you the opportunity to be one of our sponsors for the 2004 Lunch for Life Campaign. This campaign is set to launch on September 1, 2004, and although the campaign runs throughout the year, we are planning special events throughout the Pediatric Cancer Awareness Month of September. What is Lunch for Life? Lunch for Life gives kids an opportunity to help other kids just like themselves. These are kids who love to play outside, swim, fly kites, and play games, but because their young lives have been turned upside down by the words "You have cancer," they no longer can enjoy the activities of a "normal" child. Their lives are filled with doctor visits, injections, chemotherapy, radiotherapy, long days of hospitalization and countless hours of pain and, unfortunately, suffering. Until a cure is found, this scene will continue to ...