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Last Revised: 3/5/2003 UM Cancer Center Patient Education Document #0007 Mar03 Ed. Online version: http://www.cancer.med.umich.edu/learn/percpathways.htm University of Michigan Comprehensive Cancer Center Patient Education Resource Center (PERC) INFORMATION GUIDE Childhood Cancer: Neuroblastoma The purpose of this information guide is to help parents of children newly diagnosed with Neuroblastoma find sources of information and support. This list is not meant to be comprehensive, but rather to provide starting points for information seeking. The materials can be found at the Patient Education Resource Center at the University of Michigan Comprehensive Cancer Center in room B1-361. Article Available in the Patient Education Resource Center level B1 room 361 Reynolds, Patrick C. Treating High-Risk Neuroblastoma at the ...

1 The transcription factor EGR-1 promotes apoptosis of neuroblastoma cells. Short title: Role of EGR-1 in neuroblastoma cell death. Miguel Pignatelli *‡ , Rosario Luna-Medina *‡ , Arturo Pérez-Rendón * , Angel Santos † & Ana Perez-Castillo * ‡ Both authors contributed equally to this paper * .- Instituto de Investigaciones Biomédicas, Consejo Superior de Investigaciones Científicas- Universidad Autónoma, 28029-Madrid. † .- Departamento de Bioquímica y Biología Molecular, Facultad de.Medicina, Universidad Complutense, Madrid. Requests for reprints: - Ana Perez-Castillo. Instituto de Investigaciones Biomédicas, Consejo Superior de Investigaciones Científicas-Universidad Autónoma, 28029-Madrid. Spain. Phone: 34-91-5854625, Fax: 34-91-5854587, E-mail: aperez@iib.uam.es . Or ...

Clinical Categories of Neuroblastoma Are Associated with Different Patterns of Loss of Heterozygosity on Chromosome Arm 1p Jaume Mora,* Nai-Kong V. Cheung,* Brian H. Kushner,* Michael P. LaQuaglia, ‡ Kim Kramer,* Melissa Fazzari, † Glenn Heller, † Lishi Chen, § and William L. Gerald § From the Departments of Pediatrics, * Biostatistics, † Pediatric Surgery, ‡ and Pathology, § Memorial Sloan-Kettering Cancer Center, New York, New York Deletion of the short arm of chromosome 1 is fre- quently observed in neuroblastoma (NB). We per- formed loss of heterozygosity (LOH) analysis of 120 well characterized NB to better define specific regions of 1p loss and any association with clinical and bio- logical prognostic features (DNA index , MYCN ...

1 DIAGNOSTIC IMAGING IN NEUROBLASTOMA Hans Ringertz, M.D., Ph.D. INTRODUCTION Neuroblastoma is a biologically very special neoplasm that is unique to child- hood. As can be seen from Table 1 it is the fourth most common paediatric malignancy in the Nordic countries and constitutes around 6% of all malignancies in children. Neoplasm in patients below 16 years of age in the Nordic countries during the years 1985 and 2001 in order of frequency No. of new cases % 1 Leukaemia 3249 34 2 Central nervous system and intracranial and intraspinal neoplasm 2596 27 3 Lymphomas and other reticuloendothelial neoplasm 1116 11 4 Sympathetic nervous system tumours 595 6 5 Renal tumours 556 6 6 Soft tissue sarcomas 540 5 7 Malignant bone tumours 297 3 8 Germ-cell, trophoblastic ...