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1 Pancreatic Cancer By Ronald Steriti, NMD, PhD Overview Pancreatic cancer is the fifth leading cause of cancer mortality in the United States. The American Cancer Society (ACS) estimates that 29,000 Americans died from pancreatic cancer in 1998. Conventional medicine's inability to effectively treat pancreatic cancer is evidenced by survival rates of only 18% at 1 year and 4% at 5 years - one of the poorest 5-year survival rates of any cancer . The tumor results in the death of more than 98% of afflicted patients. The pancreas can be divided into two basic parts, the exocrine and endocrine pancreas. Each has a different function. The exocrine pancreas produces juices ( pancreatic enzymes) that help break down and digest food. The endocrine pancreas produces hormones (such as insulin) that regulate how the body stores and uses food. About 95% of pancreatic ...

Summer, 2002 GWCCS Cancer Support Group & Internet Resource Guide Page 1 www.gwccs.org Greater Washington Coalition for Cancer Survivors (202) 364-6422 Pancreatic , Kidney & Liver Cancer Resources Organization/Phone Logo Web Site (URL) American Foundation for Urologic Disease (410) 468-1800 http://www.afud.org/ CancerAnswers (888) 226-8287 Http:www.canceranswers.com The Cancer Group Institute (305) 651-5070 Http:www.cancergroup.com Cancer Information and Support International Http:www. cancer -info.com/pancreas Ronald Hirshberg Foundation (310) 472-6310 http:www. pancreatic .org Johns Hopkins Medical Institutions (410) 955-5718 Http:www.path.jhu.edu/pancreas Kidney ...

Review 2002 © Ashley Publications Ltd ISSN 1354-3784 1 Ashley Publications www.ashley-pub.com 1. Introduction 2. Gemcitabine – the present standard 3. Novel agents and enzymes 4. Novel immunological strategies 5. Novel strategies for treatment 6. Expert opinion and outlook Monthly Focus: Oncologic Novel treatments and therapies in development for pancreatic cancer Walter H Günzburg 1 , Matthias Löhr 2 & Brian Salmons 3 1 Institute of Virology, University of Veterinary Sciences, Veterinärplatz 1, A-1210 Vienna, Austria; 2 Molecular Gastroenterology, Department of Medicine II, Medical Faculty Mannheim, University of Heidelberg, Theodor Kutzer Ufer, D-68135 Mannheim, Germany and 3 Austrianova, Veterinärplatz 1, A-1210 Vienna, Austria ...

K -ras and p53 in Pancreatic Cancer : Association with Medical History, Histopathology, and Environmental Exposures in a Population-based Study 1 Robbert J. C. Slebos, Jane A. Hoppin, Paige E. Tolbert, Elizabeth A. Holly, John W. Brock, Rebecca H. Zhang, Paige M. Bracci, Julie Foley, Patricia Stockton, Laurie M. McGregor, Gordon P. Flake, and Jack A. Taylor 2 Laboratory of Molecular Carcinogenesis [R. J. C. S., L. M. M., J. A. T.] and Epidemiology Branch [J. A. H., J. A. T.], and Laboratory of Experimental Pathology [J. F., P. S., G. P. F.], National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709; Departments of Environmental and Occupational Health [J. A. H., P. E. T.] and Biostatistics [R. H. Z.], Rollins School of Public Health, Emory University, Atlanta, Georgia 30322; Department of Epidemiology and Biostatistics, ...

P5 CANCER . CLINICAL ASPECTS 130 Targeted Dietary Intervention after Pancreatic Resection for Malignancy. Effects on Bowel Function and Quality of Life T. Armstrong, E. Walters*, S. Varshney, C.D. Johnson University Surgical Unit and Department of Dietetics*, Southampton General Hospital, UK We have investigated long term survivors after pancreatectomy to determine whether specific dietary assessment and advice can improve gastrointestinal symptoms, bowel function and quality of life. Ten patients (7 men, median (range) age 61 (50–75) yr) were studied 16 (6–46) months after resection for malignancy, and after exclusion of recurrence by computed tomography. Detailed symptom enquiry, quality of life assessment (QoL) and dietary history were performed. All patients completed a 1 week weighed food dietary intake survey. Detailed advice was offered and patients were reassessed 8 weeks ...

The Board of Directors for the Wayne Fusaro Pancreatic Cancer Research Fund (WFPCRF) recently provided continued support for the research laboratory of David C. Whitcomb, MD PhD at the University of Pittsburgh. The WFPCRF contributed $25,000 to support Dr. Whitcomb’s pancreatic cancer genetics research. Wayne Fusaro fell victim to pancreatic cancer in July 2000 after a short 28-day illness. He was only 51 years old. His wife, Jill, has since founded the WFPCRF in his memory. Wayne is also the father of three children: Dana is the mother of one, Ashley, and works at Highmark Blue Cross/Blue Shield; Gina works at PNC Bank; and Tony works at UniFirst. Wayne was the Assistant County Manager for Pennsylvania’s Allegheny County. He enjoyed volunteering for many organizations, and the WFPCRF strives to continue his charitable work. The WFPCRF holds an annual golf outing and run/walk to raise funds and awareness ...

Recent advances on Hepato-billary- pancreatic Cancer Aichi Cancer Center International Symposium III International Conference Hall Aichi Cancer Center Nagoya, Japan December 13-14, 1996 Page 2 1 Aichi Cancer Center International Symposium III Recent advances on Hepato-biliary- pancreatic Cancer Committee of the Aichi Cancer Center International Symposium Chairperson: Makoto Ogawa Shigeru Kawamoto Noboru Shimomura Morikuni Murakami Tsuyoshi Kito Takashi Hirai Suketami Tominaga Toshitada Takahashi Masao Seto Organizing committee of the Third Symposium Chairperson : Kazuhiko Ohhashi Yasuaki Arai Takeshi Morimoto Kenzo Yasui Junichi Sakamoto Masae Tatematsu Osamu Takagi Page 3 2 Friday, December ...

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OVEREXPRESSION OF HER2 IN HUMAN PROSTATE, BREAST AND PANCREATIC CANCER CELLS AS A MOLECULAR TARGET FOR TARGETED ALPHA THERAPY Y Zhang, C Qu, Y Li, S Rizvi, C Raja & BJ Allen Center for Experimental Radiation Oncology, Cancer Care Center, St. George Hospital, Kogarah, NSW The epidermal growth factor receptor (HER2) is one member of the erbB family of transmembrane tyrosine kinases. HER2 signaling is associated with enhanced breast cancer cell proliferation. The aims of this study are to investigate if HER2 in human prostate, breast and pancreatic cancer cells is a molecular target of a new treatment with targeted alpha therapy (TAT) for metastatic cancer using the humanized monoclonal antibody, Herceptin. Human prostate cancer cell lines (PC-3, DU145 and LNCaP-LN-3), breast cancer cell lines (BT-474 and SK-BR-3) and pancreatic cancer cell lines (CAPAN-1, CFPAN-1 and PANC-1) were ...

182 Cryptosporidiosis of the biliary tract mimicking pancreatic cancer in an AIDS patient Criptosporidiose do trato biliar simulando câncer do pâncreas em paciente com AIDS Lenice do Rosário de Souza 1 , Maria Aparecida M. Rodrigues 1 , José Morceli 1 Raphael Kemp and Rinaldo Poncio Mendes 1 ABSTRACT Diarrhea caused by Cryptosporidium sp is frequent in patients with AIDS, but involvement of other organs of the digestive tract is uncommon. We report a case of Cryptosporidium -associated obstruction of the biliary tract mimicking cancer of the head of the pancreas in a 43-year-old woman with AIDS. Key-words: Cryptosporidiosis. AIDS. Biliary tract. Pancreatitis. RESUMO A diarréia causada pelo Cryptosporidium sp é muito freqüente em pacientes com aids, mas o envolvimento de outros ...

Teratogenesis, Carcinogenesis, and Mutagenesis 21:7–25 (2001) Published 2001 Wiley-Liss, Inc. † This article is a US Government work and, as such, is in the public domain in the United States of America. Risk Factors for Pancreatic Cancer : A Case-Control Study Based on Direct Interviews Debra T. Silverman* Occupational Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland The etiology of pancreatic cancer is poorly understood, partly because of the incon- sistency of findings among case-control studies of pancreatic cancer . Because of the unfavorable prognosis for pancreatic cancer , many case-control studies have been based largely on interviews with next of kin, who are known to report less reliable information on potential risk factors than original respondents. The ...