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DIALOGUE THE CURE STARTS HERE • CAMPAIGN FOR THE FUTURE FA L L / W I N T E R 2 0 0 3 3-D Imaging, Robotic System Enhances Precision for Prostate Cancer Surgery Surgeons at Strong Memorial Hospital and the James P. Wilmot Cancer Center are the first in upstate New York to use high-tech robotic systems to ensure greater precision while performing surgery to remove cancerous prostate tumors. This technology provides surgeons a three-dimensional view, giving them the feel of an open surgery while performing a minimally invasive procedure. “This system truly enhances the images and is dramatically better,” says Jean V. Joseph, M.D., urology surgeon. “The magnified 3-D images improve the accuracy and precision.” Strong recently added the daVinci Surgical System to expand laparascopic procedures in urology and cardiac surgery. ...

Harvard Center for cancer prevention Harvard school of public health 665 Huntington Avenue Boston, Ma 02115 | 617.432.0038 www.hsph.harvard.edu/ cancer | hccp@hsph.harvard.edu The Prostate The prostate is a small gland in the male reproductive system, found below the bladder and in front of the rectum. It makes fluid that mixes with sperm from the testicles. Prostate Cancer Prostate cancer occurs when cells in the prostate grow out of control. The cells clump together and form a malignant ( cancer - ous) tumor. Burden of Disease • Prostate cancer is the second leading cause of cancer death for men in the US, accounting for 37,000 deaths in 1999. • Approximately 180,000 American men will be diagnosed with prostate cancer this year. • Prostate cancer is the most common cancer among men ...

Prostate Cancer Screening A Survey of Primary Care Providers in Newfoundland and Labrador Vernon Curran, PhD Assistant Professor (Medical Education) Director of Academic Development Shirley Solberg, PhD Associate Professor Maria Matthews, PhD Assistant Professor Jon Church, PhD Associate Professor Sharon Buehler, PhD Associate Professor Julie Wells, B.Sc Research Assistant Tanya Lopez, MA Research Assistant Page 2 ii Acknowledgments This project was funded in part by the Center for Behavioural Research and Program Evaluation, University of Waterloo. The survey was supported by Newfoundland and Labrador Chapter of the Canadian Cancer Society and the Newfoundland and Labrador Medical Association. Page 3 iii Table of Contents ...

Hein Van Poppel is Chairman of the Department of Urology at the University Hospital Gasthuisberg, Katholieke Universiteit Leuven (K.U.Leuven) in Belgium, where he has been responsible for the development of urological oncology since 1985. He is a board member of the European Society of Uro- Oncology (ESOU), a faculty member of the European School of Urology (ESU) and a member of the Executive Committee of the Residency Review Committee of the European Board of Urology (EBU). Professor Van Poppel is co-ordinator of the Belgian Uro-Oncological Study Group (BUOS) and serves as Treasurer of the Genito-Urinary Group of the European Organisation for Research and Treatment of Cancer (EORTC), where he is also study co-ordinator of several prostate and kidney cancer trials. He has published more than 120 papers as first author on uro-oncological ...

Men in Mind Project newsletter 3 The key speakers were Mr Prasad Bollina, Consultant Urologist, Western General Hospital, Edinburgh, and Iain Dickson, President of the Scottish Association of Prostate Cancer Support Groups. The event was chaired by John Mackenzie, of the Scottish Association of Health Councils. Key recommendations included: 1) Increased funding for research into: (a) effective diagnostic testing (b) effective treatment and (c) the nature of the cancer 2) Ensuring accurate and impartial information is available to the general public, to enable informed choice regarding prostrate screening 3) Addressing the large number of GPs still operating on the old policy of dissuading men from screening 4) Identifying and disseminating protocols for impartial ' pre-screening counselling' to ensure informed choice ...

Gene expression profiling identifies clinically relevant subtypes of prostate cancer Jacques Lapointe a,b,c , Chunde Li d , John P. Higgins a , Matt van de Rijn a , Eric Bair e , Kelli Montgomery a , Michelle Ferrari c , Lars Egevad d , Walter Rayford f , Ulf Bergerheim g , Peter Ekman d , Angelo M. DeMarzo h , Robert Tibshirani e,i , David Botstein j , Patrick O. Brown b,k , James D. Brooks c,l , and Jonathan R. Pollack a,m Departments of a Pathology, b Biochemistry, c Urology, e Statistics, ...

Leading Prostate Cancer Expert Joins NMH Team Northwestern Memorial can now boast that it has on board the surgeon who has performed more nerve-sparing radical prostatectomies than anyone in the United States. The nerve-sparing technique means that during the surgical removal of the prostate gland, an attempt is made to spare the two cavernous nerve sheaths that produce erections. William Catalona, M.D., recently joined Northwestern as director of the clinical prostate cancer program. Last year, he presented findings on recovery of erections following this surgery on more than 1,500 of his patients. Recovery of erections occurred in 75 percent of the preoperatively potent men treated with bilateral nerve-sparing surgery and in 54 percent of the patients treated with unilateral or partial nerve-sparing surgery. "A true cure is when a patient is restored to the way he was before the diagnosis and ...

September 11, 2000 Vol. 60 No. 19 http://www.tdh.state.tx.us/phpep/ A lthough men of any age can get prostate cancer , it is detected most often in men over 50. In fact, more than 8 out of 10 men with prostate cancer are over the age of 65. Deaths from prostate cancer in Texas are about twice as common among African American men as they are among White American men (Figure 1). (Incidence data for 1998 are not yet available.) It is also most common in America and northwest- ern Europe. It is less common in Asia, Africa, Central America, and South America. Figure 1. Prostate Cancer in Texas Males, By Race/Ethnicity Incidence: 1996 1 # Cases Rate 2 Pop All Races 9,461 120.3 9,472,647 Anglo 7,063 122.1 5,488,356 African American 1,124 174.8 ...

NMH Offers Innovative Treatment for Incontinence After Prostate Cancer Loss of bladder control after prostate surgery is a devastating complication of prostate cancer . Damage to the urinary sphincter during a radical prostatectomy appears to be the primary reason for post-radical urinary incontinence. In recent years, Northwestern Memorial helped to pioneer a new treatment for men with severe post-radical prostatecomy incontinence. Called the sling procedure, the procedure involves making an incision just above the public bone and another behind the scrotum. Then, needles containing nylon sutures are passed behind the public bone, alongside the urethra and through the perineum. The sutures are firmly anchored in such a way that at least 100 cm of water-closure pressure is achieved, creating a new sphincter. Anthony Schaeffer, M.D., Chair of Urology at Northwestern Memorial Hospital, helped ...

Regional Health Education Kaiser Permanente Health Matters T he prostate is a walnut-sized gland located in front of the rectum and below the bladder. Next to skin cancer , prostate cancer is the most common type of cancer in men. At some point in their lives, 8 out of 100 men over the age of 50 will have their lives affected by prostate cancer . Of those eight, three will die from prostate cancer . The other five will not have their lives short- ened because most prostate cancers grow very slowly. What are the symptoms of prostate cancer ? Early prostate cancer usually has no symptoms. However, having trouble urinating or urinating more often may be signs of prostate cancer . These symptoms could also simply mean your prostate is enlarged, or they can ...

Center for Environmental Health Studies (617) 482-9485 44 Farnsworth Street, Boston, MA 02210 http://www.jsi.com Prostate Cancer and Exposure to Ionizing Radiation 1 Prostate Cancer and Exposure to Ionizing Radiation Summary: Evidence has been recorded of an connection between cancers of the prostate and exposure to ionizing radiation. This connection is supported by evidence from studies of nuclear workers in England who have been exposed to ionizing radiation. The National Research Council’s, on the other hand, has determined that the prostate is relatively insensitive to ionizing radiation. Prostate cancer is not designated as a “specified” cancer under the Energy Employees Occupational Illness Compensation Program Act. Historically, prostate cancer incidence has been high for Los Alamos County while prostate cancer mortality ...

Advances in Research at The Cleveland Clinic March 2003 Volume 7 No. 1 Prostate Cancer Program Sets Highest Standards to Earn Research Program of the Year Award Continued on Page 5 Prostate Cancer Program participants: Investigators contributing to the award winning prostate cancer research program are, from left, Howard Levin, M.D., Skip Heston, Ph.D., Yan Xu, Ph.D., Robert Silverman, Ph.D., Graham Casey, Ph.D., Eric Klein, M.D., Andrei Gudkov, Ph.D., Raymond Tubbs, D.O., Jay Ciezki,. M.D., and Arul Mahadevan, M.D. Participants not pictured include Robert Drecier, M.D., Tatiana Byzova, Ph.D., Ed Plow, Ph.D. and Jennifer Brainard, M.D. Inside Notations: T he Cleveland Clinic has announced that The Prostate Cancer Program, comprised of a team of investigators from the Cleveland ...

PROSTATE CANCER PROSTATE CANCER HOW MANY MEN GET PROSTATE CANCER ? • Prostate cancer is the most common type of cancer found in American men , other than skin cancer . • The American Cancer Society predicts that there will be about 180,400 new cases of prostate cancer in this country in the year 2000. • Found most often in men over 50 . Although men of any age can get prostate cancer , it is In fact, more than 8 out of ten of the men with prostate cancer are over the age of 65. • Prostate cancer is about twice as common among African-American men as it is among white American men. RISK FACTORS • Age The chance of getting prostate cancer goes up with age. • Race For unknown reasons, prostate ...

Selenium and prostate cancer Graham Lyons Introduction Evidence suggests that selenium (Se) is the most effective broad spectrum anti- cancer agent yet found. It is also involved in antioxidant defence mechanisms, thyroid metabolism, immunocompetence, mood states, and limiting the progression of severe viral diseases, including HIV and hepatitis C. Most of us do not consume enough Se to provide maximum protection against cancer . The average Australian adult intake of Se is around 75 micrograms (µg)/day, whereas optimum intake is likely to be around 250 µg/day for males and 150 for females. Several studies have shown that Se and vitamin E are particularly beneficial for male smokers. According to a proposed two-stage model of cancer prevention, which involves Se intakes that correct nutritional deficiency as well as much higher, supranutritional intakes, individuals ...

NATIONAL INSTITUTE FOR CLINICAL EXCELLENCE SPECIAL HEALTH AUTHORITY NINTH WAVE WORK PROGRAMME PROSTATE CANCER On 14 th October 2003 the Department of Health and the Welsh Assembly Government formally requested the National Institute for Clinical Excellence to prepare a clinical guideline as described in the box below. Title: Clinical guideline for the diagnosis and treatment of prostate cancer . Remit: “To prepare a guideline for the NHS in England and Wales for the clinical management of prostate cancer , to supplement existing service guidance. The guideline should cover: - the key diagnostic and staging procedures – excluding screening - the main treatment modalities including hormonal treatments (covering surgical and chemical castration) - the role of tumour specific bisphosphonates.” Page 2 ...

Hormel Researcher to Study Caloric Restriction and Prostate Cancer MINNEAPOLIS / ST. PAUL—Margot Cleary, an associate professor at the University of Minnesota’s Hormel Institute in Austin, Minn., has received a three-year, $375,000 grant from the U.S. Department of Defense Prostate Cancer Research Program to study how reduced caloric intake may prevent the development of prostate cancer , the most common cancer among men in the United States. The study will use male mice that develop prostate tumors in a manner similar to humans as a model system for determining the effects of chronic and intermittent caloric reductions on tumor growth. The study builds on earlier work by Cleary and her colleagues, in which she found—also working with mice— that intermittent caloric restriction followed by refeeding had a protective effect on mammary/breast tumor development. In that study, which was published ...

prostate cancer Hormel Researcher to Study Caloric Restriction and Prostate Cancer MINNEAPOLIS / ST. PAUL?Margot Cleary, an associate professor at the University of Minnesota?s Hormel Institute in Austin, Minn., has received a three-year, $375,000 grant from the U.S. Department of Defense Prostate Cancer Research Program to study how reduced caloric intake may prevent the development of prostate cancer , the most common cancer among men in the United States. The study will use male mice that develop prostate tumors in a manner similar to humans as a model system for determining the effects of chronic and intermittent caloric reductions on tumor growth. The study builds on earlier work by Cleary and her colleagues, in which she found?also working with mice?that intermittent caloric restriction followed by refeeding had a protective effect on mammary/breast tumor development. In that study, ...

Assemblymember FRAN PAVLEY District Office: 6355 Topanga Canyon Blvd. Suite 205 Woodland Hills, CA 91367 (818) 596-4141 (310) 395-3414 (805) 644-4141 Fax: (818) 596-4150 Capitol Office: State Capitol, P.O. Box 942849 Sacramento, CA 94249-0041 (916) 319-2041 Fax: (916) 319-2141 E-mail: Assemblymember.Pavley @assembly.ca.gov Dear Friend: The early detection of cancer and new treatments make it possible for men to live longer and healthier lives. Men diagnosed with prostate cancer can take charge of their lives and overcome much of the fear and anxiety that accompany a cancer diagnosis. Many men do not get the best treatment for their cancer because they do not act early enough and are not aware of the resources available to them. Any individual diagnosed with cancer will have questions regarding tests ...

A U D I T E D F I N A N C I A L S T A T E M E N T S A N D O T H E R F I N A N C I A L I N F O R M A T I O N Prostate Cancer Foundation (Formerly Association for the Cure of Cancer of the Prostate (CaP CURE)) Years ended December 31, 2002 and 2001 with Report of Independent Auditors Page 2 A U D I T E D F I N A N C I A L S T A T E M E N T S Prostate Cancer Foundation (Formerly Association for the Cure of Cancer of the Prostate (CaP CURE)) Years ended December 31, 2002 and 2001 with Report of Independent Auditors Page 3 Prostate Cancer Foundation (Formerly Association for the Cure of Cancer of the Prostate (CaP CURE)) Audited Financial ...

RESOURCE SUPPORT For additional information about prostate cancer , the following resources are available: National Cancer Institute Cancer Information Service (CIS) 1-800-4- CANCER Cancernet www.cancernet.nci.nih.gov The Cancer Information Service (CIS) and Cancernet are National Cancer Institute programs that provide a nationwide telephone service and web site for cancer patients, their families and friends. American Cancer Society 1-800-ACS-2345 www. cancer .org The American Cancer Society (ACS) is a voluntary organization with a national office in Atlanta, Georgia, and local facilities across the country. It supports research, patient education programs, and other services for family members. It also publishes and distributes free booklets on colon cancer and home care. AmeriPath, Inc. www.ameripath.com AmeriPath, Inc., is a ...

Brochure More information from http://www.researchandmarkets.com/reports/4617 Strategic Perspectives: Prostate Cancer - Issues in Second-line, Brachytherapy and Hormone-Refractory Prostate Cancer Treatments Description: Although highly treatable at initial stages, there remains lack of consensus in second- line and hormone-refractory prostate cancer therapies. As a result, treatment practices vary considerably from country to country. Furthermore, brachytherapy, despite its growing popularity in recent years, has not been widely adopted. This study presents the results of extensive physician research to identify existing treatment regimens, profiles new drugs in development, and highlights areas of unmet need.Results of extensive physician research across the seven major markets: US, Japan, Germany, France Italy, Spain and UKMain treatment regimens in second-line ...

Brochure More information from http://www.researchandmarkets.com/reports/1296 Prostate Cancer Opinion Leader Forum, 2002 Description: The subject of this report is the management of prostate cancer in the US. Interwoven throughout the report are comments regarding the management of benign prostatic hyperplasia which, although not related to prostate cancer , is often mentioned tangentially with prostate cancer . More specifically, however, the subject of prostate cancer , and to a lesser degree benign prostatic hyperplasia, has been approached primarily through in-depth interviews (a forum) with clinical and academic authorities, pharmaceutical industry and medical device manufacturing executives, and other experts in the field of prostate cancer management. The objective of the report is to produce a close-in snapshot of the current opinions ...

FACT SHEET - PROSTATE CANCER IN AUSTRALIA Facts and figures* • prostate cancer is the most common form of cancer in Australian (and Tasmanian) men after non-melanoma skin cancer • a total of 10,232 new cases of prostate cancer were diagnosed in Australia in 1999 and 273 new cases in Tasmania in 2000 (the latest years for which statistics are available) • after lung cancer , prostate cancer causes more deaths among Australian men than any other kind of cancer • a total of 2,512 Australian men died from prostate cancer in 1999 (71 in Tasmania in 2000) • one in 11 Australian men will develop prostate cancer by the age of 75 • prostate cancer is rare before the age of 45 • almost 90% of prostate cancers occur in men aged 60 years and over, and 97% of deaths from ...

The PSA Decision Is testing for prostate cancer right for you? Created by Stacey L. Sheridan, MD, MPH , Michael P. Pignone, MD, MPH, and Russell P. Harris, MD, MPH Division of General Medicine University of North Carolina at Chapel Hill Funding Source: University Research Council Small Grant from the Lineberger Comprehensive Cancer Center Fincancial Conflicts: None Page 2 The PSA Decision The prostate is located under the urinary bladder. Prostate Bladder Doctors disagree about whether having a test to look for prostate cancer is a good idea. Much of the disagreement is due to how much weight or value each doctor places on the information we know about prostate cancer and the testing process. These cards will give you information about the following ...

prostate cancer Please Click on the Following Links to Access CASODEX® (Bicalutamide) Tablets and ZOLADEX® (Goserelin Acetate Implant) Full Prescribing Information CASODEX® (Bicalutamide) Tablets Full Prescribing Information ZOLADEX® (Goserelin Acetate Implant) 3.6 Mg Depot Full Prescribing Information ZOLADEX® (Goserelin Acetate Implant) 10.8 Mg Depot Full Prescribing Information Revised October 2003 Overview of Prostate Cancer Management Table of Contents Prostate cancer statistics (epidemiology) Risk factors Endocrinology Screening Diagnosis Treatment options Definitive therapy with curative intent Hormonal therapy ZOLADEX® (goserelin acetate implant) Versus orchiectomy With radiotherapy Antiandrogens (CASODEX® [bicalutamide] ...

The prostate The prostate is about the size of a walnut and is located just below the bladder. It surrounds the tube that carries urine from the bladder and out through the penis (the urethra). See the diagram, overleaf. Changes to the prostate Normally, cells grow and multiply only when the body needs them to. Cancer develops as a result of a breakdown in this process, leading to cells growing in an uncontrolled way. The mass of excess cells forms a tumour (growth), which may be benign or malignant. The tumour is described as malignant if it is able to invade other healthy tissue. The peripheral (outer) zone of the prostate is the area most susceptible to developing cancer . Risks and causes Prostate cancer is rare in men under 50 years old. However, the risk increases steadily with age and by the time they are 80, ...

prostate cancer Extra-Cranial Radiosurgery For Prostate Twyla Willoughby, M.S. M.D. Anderson Cancer Center Orlando Introduction: Prostate cancer has been treated with radiation therapy for many years. Traditionally these treatments would comprise of static gantry fields with slight blocking in order to spare some of the rectum and the bladder from getting full dose. Early prostate cancer treatment was designed to target the prostate , seminal vesicles and the pelvic lymphatic system. Today, with early screening, many of the patients who present with prostate cancer have localized disease in the prostate gland only. In these cases it is only necessary to try to target the prostate itself. This work has developed with the help of imaging and biopsy studies along with early screening programs to offer ...

prostate cancer Prostate Cancer : Screening and Recommendations “We must move toward the development of health messages that reflect the best medical knowledge to date on prostate cancer to meet the information needs of primary care physicians and the public.” --David Satcher, MD U.S. Surgeon General Learning Objectives Explain the rationale for prostate cancer (CaP) screening Name risk factors for prostate cancer Describe strengths and limitations of DRE and PSA for early detection of CaP List the risks and benefits of screening with PSA including likely treatment outcomes Explain differences in screening guidelines Identify costs related to a CaP screening program Scope of the Problem Most common noncutaneous cancer among U.S. men Second leading cause of cancer deaths ...

PROSTATE CANCER : Surgery and radiation cause different complications. Researchers led by a team from the National Cancer Institute compared the side effects of treatments for localized prostate cancer in 1,591 men between the ages of 55 and 74. Two years after treatment, the 1,156 men who had surgery had more problems with urinary incontinence (9.6 percent vs. 3.5 percent) and impotence (79.6 percent vs. 61.5 percent) compared to those who had radiation. The 435 men who had radiation had more bowel problems such as diarrhea (37.2 percent vs. 20.9 percent). Ninety-two percent of all patients said they would choose the same treatment again. This is the first study to directly compare side effects of radiation vs. surgery for the treatment of localized prostate cancer in a diverse group of patients. The men were surveyed about side effects at six, 12 and 24 months after diagnosis. The characteristics ...