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5.23 11/10/03 Page 1 Early Prostate Cancer : Questions and Answers 1. What is the prostate ? The prostate is a gland in the male reproductive system. The prostate makes and stores a component of semen and is located near the bladder and the rectum. The prostate surrounds part of the urethra, the tube that empties urine from the bladder. A healthy prostate is about the size of a walnut. If the prostate grows too large, the flow of urine can be slowed or stopped. Key Points • The prostate is a gland in the male reproductive system (see Question 1). • The most common risk factor for prostate cancer is age (see Question 3). • Prostate cancer often does not cause symptoms for many years. By the time symptoms occur, the disease may have spread beyond the prostate (see Question 4). • The symptoms of prostate cancer can also be caused by noncancerous ...

Where to Start Sources of Information on Prostate Cancer Suggestions for resources when you begin to look for information about prostate cancer . Prepared by the Ninon Bourque Patient Resource Library The Ottawa Hospital Regional Cancer Centre 501 Smyth Road, Ottawa, ON, K1H 8L6 613-737-7700 ext 70107 These resources are provided for information purposes only and are not intended as a substitute for medical care. Inclusion of a resource does not imply endorsement by The Ottawa Hospital. If you have any questions about your healthcare, please consult your healthcare provider. If you would like to have more information about this topic, please contact the Ninon Bourque Patient Resource Library at 613-737-7700 ext. 70107 or consumerhealth@ottawahospital.on.ca . Basic Information Prostate cancer : what you need to know . A 12-page booklet providing ...

Prostate Cancer Early Detection (Page 1 of 6) The objective of this guideline is to maximize the detection of prostate cancer not to address whether or not early detection is appropriate. It is neither the intent nor suggestion that all men diagnosed with prostate cancer require treatment. It is inherent that as we maximize the detection of prostate cancer , we will increase the detection of currently defined significant and insignificant prostate cancers. Due to the unique biology of prostate cancer , over-treatment is of concern because the results can potentially impact the quality of life. The value of prostate cancer screening is controversial. For those men who, after informed consent, elect to undergo early detection, these general guidelines, in combination with patient preference, are the majority recommendations based on expert opinion of the GU Center Faculty at the University of Texas, MDACC. ...

Know your body and keep it safe Prostate Problems Guide to Page 2 2 3 8 out of 10 men don’t know where their prostate gland is. The prostate gland is found at the bottom of your bladder wrapped around the tube (called the urethra) which carries urine out of the penis. It’s about the size of a walnut and its job is to make the liquid that carries your sperm. 8 out of 10 men will need treatment for prostate problems. The prostate starts to develop at puberty and at around the age of 40 the prostate grows again, which for many men is when problems may begin. The unwanted growth is called “Benign Prostatic Hyperplasia” or BPH for short. It is not cancer and it’s rare before the age of 50. But, next ...

Chromosome aberrations in peripheral blood lymphocytes from patients with primary prostate cancer before radiotherapy Hana Hofman-Hüther 1 , Oliver Balzer 2 and Patricia Virsik-Köpp 2 1 Dept. Radiotherapy and Radiooncology; 2 Dept. Hygiene and Environmental Medicine Medical Faculty, University of Goettingen, Germany Spontaneous level of chromosome aberrations is considered to be indicative of inherent cancer predisposition, which plays an important role in cancer incidence. We have studied spontaneous chromosome aberrations in peripheral blood lymphocytes of patients with prostate cancer before their treatment with conventional therapy. Twelve patients with Stage T1-T2 primary prostate cancer were included in this study. Four healthy male donors served as controls for comparison, and the yields of chromosome ...

Center for Environmental Health Studies (617) 482-9485 44 Farnsworth Street, Boston, MA 02210 http://www.jsi.com Prostate Cancer and Exposure to Ionizing Radiation 1 Prostate Cancer and Exposure to Ionizing Radiation Summary: Evidence has been recorded of an connection between cancers of the prostate and exposure to ionizing radiation. This connection is supported by evidence from studies of nuclear workers in England who have been exposed to ionizing radiation. The National Research Council’s, on the other hand, has determined that the prostate is relatively insensitive to ionizing radiation. Prostate cancer is not designated as a “specified” cancer under the Energy Employees Occupational Illness Compensation Program Act. Historically, prostate cancer incidence has been high for Los Alamos County while prostate cancer mortality has been low compared ...

WHAT EVERY MAN SHOULD KNOW ABOUT PROSTATE CANCER Prostate cancer often has no symptoms. This is why screening is so important for all men starting as young as age 40, particularly if they are at high risk due to family history or racial background. Black men have the highest incidence of prostate cancer , followed by Hispanics. Many current guidelines specify that screening for all men should begin at age 50. Any persistent increase in PSA over time at any level, even within the normal range, should be investigated to rule out prostate cancer . If patients and doctors were to keep a PSA record or a graph, noting any changes and noting the trend over time in PSA values, countless lives would be saved. The quality of life for many men diagnosed with prostate cancer is better preserved with early detection of the disease versus diagnosis with advanced disease. Prostate cancer detected early provides many options ...

PROJECT 1 – MOLECULAR PREDICTORS OF PROSTATE CANCER PROGRESSION & MORTALITY Prostate cancer (CaP) is the most frequently diagnosed solid tumor and the second leading cause of cancer deaths among U.S. men. Despite the substantial morbidity and mortality associated with CaP, limited attention has been focused on elucidation of factors that predict clinical disease progression or mortality. Environmental and genetic factors may play a role in the development of aggressive, life-threatening CaP. We hypothesize that variant alleles in genes involved in the androgen/growth factor/antioxidant pathways confer a higher risk for disease progression and mortality. Specifically, we propose to genotype a population-based cohort of CaP patients to address the following hypotheses: 1) Heterozygotes and homozygotes for the valine allele (V89L) in the SRD5A2 gene have an increased risk of prostate cancer progression and mortality; ...

PROJECT 4 –TRANSCRIPTOME & PROTEOME STRATIFICATION OF PROSTATE CANCER ADENOCARCINOMA PHENOTYPES Prostate cancer is a complex disease that presumably stratifies into different types of cancers with distinct progression rates, metastatic potentials and prognostic outcomes. We hypothesize that histologically similar primary prostate carcinomas can be stratified into distinct categories of clinical behavior based upon profiles of their expressed genes . We will determine the gene expression profiles of prostate carcinoma that correlate with clinical phenotype of progression or non-progression as determined by PSA-free survival at 5 years post-therapy. The expression profiles from the normal and neoplastic tissues of 100 individuals that have undergone radical prostatectomy will be determined. Outcomes will be measured by following serial PSA measurements for recurrent disease. Correlations of individual ...

Family Issues in Policy and Culture A Web site of Focus on the Family About Us | Contact | Press Citizen Link Extras Features Citizen Magazine Issue Archive Subscribe/Join Family Policy Councils State Councils Family News In Focus Listen Find a Station Focus on Social Issues Abstinence Policy Bioethics/Sanctity of Life Constitution & Govt. Education Gambling Homosexuality & Gender Marriage & Family Origins Persecution Political Islam Pornography Worldview & Culture Support the Ministry Donate Online Give Monthly Volunteers Creative Giving Pray for Focus June 17, 2005 Lawmakers, Celebs Target Prostate Cancer by Bill Wilson, Washington, ...

Prostate Cancer An estimated 232,090 American men will be diagnosed with prostate cancer in 2005. About 70 percent of all diagnosed prostate cancers are found in men older than 65. PREVENTION • Lead a healthy lifestyle and talk to your health care professional about screening. • Exercise regularly. • Eat a diet low in fat and high in fruits, vegetables and whole grains. RISK • Men, particularly African-American men, and men over age 50 • Men with a family history of prostate cancer SYMPTOMS In the early stages, there are usually no symptoms. Some men experience the following symptoms: • Frequent urination, especially at night • Trouble starting or stopping urine flow • Weak or interrupted urine flow • Inability to urinate • Pain or burning sensation while urinating • Blood in the urine • Constant pain in lower back, pelvis or upper thighs ...

Research and Programs That Touch People 1.800.63.DONATE www.kidneyurology.org What You Should Know About Prostate Cancer 1250 Broadway, Suite 2001 New York, NY 10001 212.629.9770 or 1.800.63.DONATE fax 212.629.5652 Visit our web site at www.kidneyurology.org The Kidney & Urology Foundation of America, Inc. is a national, not-for-profit organization dedicated to helping people avoid the debilitating effects of kidney and urologic diseases - disorders affecting as many as 70 million Americans today. By funding research, medical conferences, and interdisciplinary hospital initiatives, the Kidney & Urology Foundation provides the leadership necessary to promote a better understanding of kidney and urologic diseases. We are committed to making research and resources accessible to patients and their families, as well as ...

Improving the Experience of Prostate Cancer Surgery Robotic Prostatectomy at Wake Forest University Baptist Medical Center Improving the Experience of Prostate Cancer Surgery Robotic Prostatectomy at Wake Forest University Baptist Medical Center Piedmont Triad Edition Page 2 Improving the Experience of Prostate Cancer Surgery Robotic Prostatectomy at Wake Forest University Baptist Medical Center cover story AccordingtotheAmericanCancerSociety,prostatecancercontinuesto be the most common form of cancer found in men in the United States. In fact,prostatecanceraloneaccountsforone-thirdofallcancersdiagnosedin men,withapproximately180,000newcaseseachyear.Thesecondleading cause of cancer death after lung cancer — one of six men in the U.S. will be diagnosed with this disease during their ...

English April 2002 [BHC-6055] 1 / 2 D E P A R T M E N T Prostate cancer : what are the treatment options? Every man has a prostate , a small gland that produces some of the fluid in semen. It is found at the base of the bladder and surrounds the urethra (the tube which takes urine from the bladder to the penis). At some time in their lives, one in ten men in Australia will be diagnosed with prostate cancer . This usually affects men after the age of 50, and becomes increasingly common over the following dec- ades. However, this cancer tends to grow slowly - most men who have it don’t die from the disease. What is prostate cancer ? It’s normal for the prostate to get bigger after middle age. This can cause symp- toms, such as needing to pass water more often. But an enlarged prostate isn’t the same as cancer . Cancer is a malignant growth in the ...

Chinese April 2002 [BHC-6055] 1 / 2 D E P A R T M E N T ½ : 8 ? Prostate cancer : what are the treatment options? ½, 8 ¼ + q , ? , 8( 7 )q! ? 2 ? ½q8 50 ? , ? 8q% (/ – ½ (q ½ ? ?, ½ q , àq ½? q/ ½ /q, ½?q ½?, ? ? q ½ 8 q ½ ? ,Æ Aq2/8ü ? q Æ: Ã : ¼ ½ q ä : X- ä+q (Brachytherapy) : ä—8 8 ? +q /q — ä ½ q /A?8 q( : ? 70 ?, (?,q) äß: / 8Ç 2 ýq + % ½, + ( q( ? / q8 ? (q Page 2 NSW Multicultural Health Communication Service Website: http://mhcs.health.nsw.gov.au e-mail: mhcs@sesahs.nsw.gov.au Page 2 ...

Vietnamese April 2002 [BHC-6055] 1 / 1 DEPARTMENT Chng ung thi tuy’n ti÷n liŸt vø phiÍng phæp ch?a trfi Prostate cancer : what are the treatment options? Nam giÎi cfl mÈt tuy’n nh· s¿n xu`t ra tinh dfich g„i lø mÈt tuy’n ti÷n liŸt. Tuy’n nøy n˜m Ì {æy bøng quang (b„ng {æi) vø bao quanh Âng ti’t niŸu (lø mÈt Âng nh· dÕn niÎc ti?u t˜ bøng quang ra diÍng vŒt). T¬i Æc, Ì mÈt thÏi {i?m nøo {fl trong {Ïi mÈt ngiÏi {øn ‰ng, c trong 10 ngiÏi l¬i cfl mÈt ngiÏi mƒc ph¿i chng ung thi tuy’n ti÷n liŸt. Chng nøy thiÏng x¿y ra Ì nh?ng ngiÏi tr‘n 50 tuÁi vø thiÏng gia tvng trong nh?ng thŒp ni‘n k’ {fl. Tuy nhi‘n, chng ung thi tuy’n ti÷n liŸt cfl khuynh hiÎng phæt tri?n chŒm vø nh?ng ngiÏi bfi ung thi kh‰ng ch’t v¤ bŸnh nøy. Ung thi tuy’n ti÷n liŸt lø g¤? ThiÏng Ì vøo tuÁi trung ni‘n (t˜ 40 trÌ l‘n), tuy’n ti÷n liŸt nÌ lÎn hÍn. V`n {÷ nøy cfl th? gy ra mÈt sÂ triŸu chng, ch?ng h¬n nhi ...

prostate cancer Study proves new drug fights cancer in prostate Drug developed in Vancouver blocks protein that helps tumours fight treatment Pamela Fayerman Vancouver Sun Thursday, September 08, 2005 CREDIT: Ian Lindsay, Vancouver Sun Dan Julien volunteered to be treated with a 'smart drug' for prostate cancer at Vancouver General Hospital. Tests show it worked. VANCOUVER - After a surgeon removed a cancerous prostate gland from Dan Julien, a gram of the tumour was frozen, ground into a fine powder, and analysed to determine if a "smart drug" developed by doctors at the Vancouver General Hospital's Prostate Centre got into the tissue to do what was intended. It had. The drug, called OGX-01, inhibited the production of a protein called clusterin that protects cancer cells. The so-called ...

Surviving prostate cancer By Christian Toto THE WASHINGTON TIMES When Poolesville resident John L. Willey first learned he had prostate cancer , he went so far as to trail a urologist out of his office and into the building's elevator to get answers as quickly as possible. Mr. Willey may be impulsive, but his instincts are sound. The quicker a prostate cancer patient acts, the better the chance for a successful recovery. It's a message Mr. Willey, 60, spreads as a member of the board of directors of the National Prostate Cancer Coalition in the District. "It's important people understand what they need to do -- act," Mr. Willey says. That's because various health organizations report 1 in 6 men will get prostate cancer at some point in their lives. The disease typically strikes men older than 50, though cases in younger men have been discovered. In its ...

PROSTATE CANCER PATIENTS BENEFIT FROM NEW THERAPY AT THE MEREDITH AND JEANNIE RAY CANCER CENTER Prostate cancer patients are benefiting from brachytherapy, a new technology available at the Meredith and Jeannie Ray Cancer Center. Prostate brachytherapy is a promising new treatment in the fight against prostate cancer , and the Meredith and Jeannie Ray Cancer Center is proud to offer to our patients. “We are proud to offer this service to our prostate cancer patients. Brachytherapy is a minor surgical procedure and gives prostate cancer patients in Laramie and southeastern Wyoming another treatment option for localized prostate cancer ,” explains center medical oncologist/hematologist, Clinton Merrill, MD. “It represents another important step forward in our ongoing efforts to bring state-of-the-art cancer care as close to home as possible to residents of this region.” ...

Monash Commercial Pty Ltd ACN 095 891 722 Ground Floor, Administration 3b Monash University, Victoria 3168, Australia Telephone: (+61 3) 9905 9515 Facsimile: (+61 3) 9905 5030 www.moncommercial.com OPPORTUNITY PROFILE Prognostic Markers for Prostate Cancer Technology / Product: The technology involves multiple predictive markers with the potential to distinguish between slow growing and aggressive prostate cancer . Currently there are no adequate prognostic markers for prostate cancer . Future products will include: • Tissue-based diagnostic test to be used on prostate biopsy and surgical tissues • Blood-based diagnostic test to be used regularly to monitor disease status Advantages will be to identify patients who need surgical prostate removal and appropriate chemotherapy treatment, versus patients with latent cancer that can be monitored with ...

LovelandFYI- Prostate Cancer Foundation hopes to increase awareness of men’s disease Complete Your Week—Subscribe Today! Don't miss the complete coverage that will be yours with 7-day convenient home- delivery of the Reporter-Herald. News and information from Loveland, Colorado LovelandFYI Home News Local & Regional Nation & World Business Sports Obituaries Community Calendar Opinion Editorial Poll Results Marketplace Classifieds Submit an Ad Find a Car Real Estate Coupons Entertainment Cover Story Dining Guide Home | Local & Regional News | Sports | Business | Opinion | Community ...

Department of Defense US Army Medical Research and Materiel Command Fiscal Year 2002 Prostate Cancer Research Program Awards List Table of Contents Introduction Fiscal Year 2002 Prostate Cancer Research Program Funded Awards RESEARCH AWARDS Consortium Awards Health Disparity Research – Prostate Scholar Awards Idea Development Awards New Investigator Awards TRAINING/RECRUITMENT AWARDS Health Disparity Training - Prostate Scholar Award: Predoctoral Traineeship Postdoctoral Traineeship Awards Fiscal Year 2002 Prostate Cancer Research Program Participants Peer Reviewers Integration Panel Members Ad Hoc Programmatic Reviewers Glossary of Terms Page 2 Introduction The US Army Medical Research and Materiel Command (USAMRMC) ...

Department of Defense US Army Medical Research and Materiel Command Fiscal Year 2003 Prostate Cancer Research Program Awards List Table of Contents Introduction Fiscal Year 2003 Prostate Cancer Research Program Funded Awards RESEARCH AWARDS Exploration: Hypothesis Development Award Exploration: Resource Development Award Health Disparity Research – Prostate Scholar Awards Idea Development Awards New Investigator Awards TRAINING/RECRUITMENT AWARDS Health Disparity Training - Prostate Scholar Award HBCU Collaborative Partnership Award Postdoctoral Traineeship Awards Physician Research Training Award Fiscal Year 2003 Prostate Cancer Research Program Participants Peer Reviewers Integration Panel Members Ad Hoc Programmatic Reviewers Glossary ...

Clark County Health Department 2003 Prostate Cancer Clark County and Washington State, 1994 through 2001 Status: - Clark County's prostate cancer incidence rate has declined since the early 1990's while the statewide rate is showing a slight increase in recent years.(3) -The incidence rate generally increased with age until 70 to 79 years of age. In most age groups the risk of prostate cancer was higher in men statewide compared with Clark County men.(3) - The prostate cancer death rates in both the county and the state remained steady and were close to meeting the Healthy People 2010 target of fewer than 28.7 deaths per 100,000 population.(4,5,6) - The majority of persons diagnosed with prostate cancer were identified in the early stages of the disease indicating the presence of effective screening programs in this county and statewide. (3) What we ...

NC OFFICE • BATTELLE • CENTERS FOR PUBLIC HEALTH RESEARCH & EVALUATION 100 CAPITOLA DR, SUITE 301 • DURHAM, NC 27713 • 1-800-4AG-STUDY Prostate Cancer Spring 2005 Prostate Cancer Prostate cancer is one of the diseases of particular interest to the Agricultural Health Study because it is the most common cancer among American men and because it has been reported in other studies to be high among farmers. Does research in the Agricultural Health Study indicate that pesticide applicators are at increased risk for prostate cancer ? Research in the Agricultural Health Study shows that the incidence of prostate cancer among licensed restricted-use pesticide applicators is slightly higher (14%) than it is for other men in North Carolina and Iowa. Risk factors observed in other studies—age and a family history of ...

8 9 With new funding from the US Army Medical Research and Materiel Command (USAMRMC), which has a mandate to ‘provide solutions to medical problems’ for the military, both on and off the battlefield, Pamela Russell and her team are expanding their research into these two areas. “The first study will investigate the role of genes thought to be involved in the spread of prostate cancer to other, more life-threatening parts of the body,” said Pamela Russell, “while the second project is concerned with new treatments for prostate cancer that seek to target cancer cells while ignoring their healthy neighbours.” Researchers already know that errors in genetic material or DNA are responsible for all cancers. Previous studies at the Oncology Research Centre have shown that additional genetic errors might also explain why ...

Leave for Prostate Cancer Screening From NYS Department of Civil Service Attendance & Leave Manual Policy No. 2005-01 Legislation enacted in July 2005 (Chapter 237, Laws of 2004) amended the Civil Service Law to entitle employees to take up to four hours of paid leave annually for screening for prostate cancer . This provision took effect on October 25, 2004. A copy of this legislation is attached. Specifically, a new section of 159-c was added to the Civil Service Law to entitle State officers and employees to paid leave without charge to leave credits for prostate cancer screening. Employees are not required to have Attendance Rules coverage to be granted for this leave with pay. The benefit became available to employees on October 25, 2004 for the remainder of the 2004 calendar year. Beginning January 1, 2005, the benefit because available for the full calendar year. Leave for this prostate ...

www.imego.com Imego AB, Arvid Hedvalls Backe 4, SE-411 33 Gothenburg, Sweden Tel. +46 (0) 31 750 18 00. Fax. +46 (0) 31 750 18 01 Diagnosis of prostate cancer A fast and simple diagnosis of cancer decreases hospital care costs and permits mass screening of populations, and thereby, earlier diagnoses.The need for such an instrument exists in particular when it comes to diagnosing prostate cancer .The appearance of prostate cancer has increased dramatically, and great amounts of resources are being placed in treatment. Early diagnosis would be accompanied in part by large economic savings for society and, in another part, would contribute to improved life quality for patients whose treatment would be considerably more merciful. Working together, Imego AB and CanAg Diagnostic AB are developing a new chip based analysis instrument for quantity detection of cancer . It will replace ...

Don’t let prostate cancer be a man’s last order Prostate cancer is the most common male cancer in the UK, with over 27,000 men diagnosed each year and 10,000 men dying. Despite these statistics thousands of men over 45 do not know they have a prostate gland, what it does or how it can go wrong. To raise awareness of prostate cancer and the prostate gland, The Prostate Cancer Charity is launching a ‘’Real Man’’ pub campaign during its Prostate Cancer Awareness Week 21 st March-27 th March 2005. We have designed special drip mats and posters for community pubs whose customers are mainly men over 45, encouraging them to the “Real Man Test”, a fun quiz which asks them to answer questions, enter a prize- winning competition and learn about the prostate gland. If you live in Bradford, Birmingham, Bristol, Liverpool or Glasgow you can help ...

P.A.C.E. #: 030-516-05 FL#: 0000516 WEBINAR CONTINUING EDUCATION Establishing a New Standard of Care for Prostate Cancer Detection and Management-PSA/fPSA 1. The most common diagnosed cancer in men is a. Melanoma b. Prostate cancer c. Lung d. Colon e. Urinary bladder 2. In screening for prostate cancer , raising the cutoff will decrease the false positive rate and a. Sensitivity will increase b. Sensitivity will decrease c. Sensitivity will not change d. True negatives will increase 3. A male 50-75 years of age with a nonsuspicious DRE and a total PSA > 10 ng/mL is at what risk of prostate cancer ? a. 1% b. 5% c. 25% d. 75% 4. Most PSA circulating in blood is a. Quickly degraded by a 1 -antichymotrypsin b. Free (not bound to other proteins) c. Bound to albumin d. Bound to a ...