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1672 Main St. Ste. E #264 • Ramona, CA 92065 • Tel: 760.789.8928 • Fax: 760.789.8929 • Toll Free: 800.475.1955 • www.proteinbiotechnologies.com HUMAN STOMACH CANCER TISSUE ARRAY Catalog Number: TMA-094 Each two (2) dots from two different tissue spots represents one single specimen that was pathologically selected and confirmed (Gastric ulcer tissue array) Cases: 14 Cores: 24 Diameter: 1.5mm Thickness: 5 µm Standard IHC: CK confirmed Layout : 4 x 6 1 2 3 4 5 6 A 1 2 3 4 5 6 B 7 8 9 10 11 12 C 13 14 15 16 17 18 D 19 20 21 22 23 24 Core No. Location Tissue Diagnosis Grade Sex Age 01 A1 Stomach Chronic gastric ulcer ...

1672 Main St. Ste. E #264 • Ramona, CA 92065 • Tel: 760.789.8928 • Fax: 760.789.8929 • Toll Free: 800.475.1955 • www.proteinbiotechnologies.com HUMAN STOMACH CANCER TISSUE ARRAY Catalog Number: TMA-105 Each three (3) dots from three different tissue spots represents one single specimen selected and pathologically confirmed. ( Stomach Adenocarcinoma tissue array) Cases: 22 Cores: 63 Diameter: 1.5mm Thickness: 5 µm Standard IHC: L-CK confirmed Layout : 7 x 9 1 2 3 4 5 6 7 8 9 A 1 2 3 4 5 6 7 8 9 B 10 11 12 13 14 15 16 17 18 C 19 20 21 22 23 24 25 26 27 D 28 29 30 31 32 33 34 35 36 ...

1672 Main St. Ste. E #264 • Ramona, CA 92065 • Tel: 760.789.8928 • Fax: 760.789.8929 • Toll Free: 800.475.1955 • www.proteinbiotechnologies.com HUMAN STOMACH CANCER TISSUE ARRAY Catalog Number: TMA-106 Each three (3) dots from three different tissue spots represents one single specimen selected and pathologically confirmed. ( Stomach Adenocarcinoma tissue array) Cases: 22 Cores: 63 Diameter: 1.5mm Thickness: 5 µm Standard IHC: L-CK confirmed Layout : 7 x 9 1 2 3 4 5 6 7 8 9 A 1 2 3 4 5 6 7 8 9 B 10 11 12 13 14 15 16 17 18 C 19 20 21 22 23 24 25 26 27 D 28 29 30 31 32 33 34 35 36 ...

1672 Main St. Ste. E #264 • Ramona, CA 92065 • Tel: 760.789.8928 • Fax: 760.789.8929 • Toll Free: 800.475.1955 • www.proteinbiotechnologies.com HUMAN STOMACH CANCER TISSUE ARRAY Catalog Number: TMA-104 Each dot represents a NORMAL tissue spot from one individual specimen that was selected and pathologically confirmed( Stomach Adenocarcinoma tissue array) Cases: 63 Cores: 63 Diameter: 1.5mm Thickness: 5 µm Standard IHC: Actin confirmed Layout : 7 x 9 1 2 3 4 5 6 7 8 9 A 1 2 3 4 5 6 7 8 9 B 10 11 12 13 14 15 16 17 18 C 19 20 21 22 23 24 25 26 27 D 28 29 30 31 32 33 34 35 36 ...

1672 Main St. Ste. E #264 • Ramona, CA 92065 • Tel: 760.789.8928 • Fax: 760.789.8929 • Toll Free: 800.475.1955 • www.proteinbiotechnologies.com HUMAN STOMACH CANCER TISSUE ARRAY Catalog Number: TMA-095 Each dot represents a DISEASED tissue spot from one individual specimen that was selected and pathologically confirmed ( Stomach Carcinoma Tissue Array) Cases: 0 Cores: 72 Diameter: 1.5mm Thickness: 5 µm Standard IHC: CgA confirmed Layout : 8 x 9 1 2 3 4 5 6 7 8 9 A 1 2 3 4 5 6 7 8 9 B 10 11 12 13 14 15 16 17 18 C 19 20 21 22 23 24 25 26 27 D 28 29 30 31 32 33 34 35 36 E ...

INTRODUCTION n most countries cancer incidence and mortality rates are constantly increasing, and according to available predic- tions this tendency will persist in the nearest future. At the Congress of the International Union Against Cancer in Rio de Janeiro in 1998, a progressive increase in the number of incident cancer cases in the world was noted: 6 million cancer cases in 1975, 7.6 million in 1985, 8.1 million in 1990, and the expected rate in 2010 is 13 million incident cancer cases. The fact that this increase is taking place on the background of doubtless achieve- ments of modern oncology in diagnostics and treatment of tumors provides reason enough to primary and secondary cancer pre- vention to be the main means of changing this tendency. Even though the etiology and pathogenesis of malignant neo- plasms remain unclear, the available scientific information about multiple carcinogenic ...

Background Information Stomach Cancer Stomach (gastric) cancer affects about two of every 10,000 people. Stomach cancer afflicts men twice as often as women, and it is more common among African-Americans.The diag- nosis of stomach cancer is often delayed due to a lack of symptoms in its early stages and/or the self-treatment of symptoms. Risk factors for stomach cancer include the following: • A family history of stomach (gastric) cancer • A history of Helicobacter pylori gastritis • A history of gastric polyps • Decreased gastric acid Symptoms of stomach cancer include the following: • Loss of appetite • Difficulty in swallowing • Nausea • Vomiting blood • Abdominal pain • Diarrhea ...

One year Survival Following Diagnosis of Stomach Cancer Notes Survival following diagnosis of stomach cancer One-year and 5-Year directly age-standardised relative survival rates 15 to 99 years One year survival patients diagnosed 1995-97 (followed up to 31 December 1998) Five year survival patients diagnosed 1995-97 (followed up to 31 December 2002) Relative survival rate at one and five years after diagnosis for patients diagnosed in England and Wales during the respective year/period. Cancer patients have higher mortality than the general population, but they do not all die of cancer . The relative survival rate is the ratio of the survival rate actually observed among the cancer patients and the survival that would have been expected if they had only had the same overall mortality rates as the general population. Thus, if five-year survival is 60% among a group of cancer patients of whom 90% ...

MORTALITY FROM STOMACH CANCER BY PCT Notes: Mortality from stomach cancer (ICD10 C16): Data are based on the original underlying cause of death. Data are based on ONS population estimates (February 2005 release). Indirectly standardised ratios (SMR) All ages 2001-03 (Pooled) England 2001-03 = 100 (Standard rates are England annual age-specific rates 2001-03) Highlights: Bedfordshire Heartlands PCT and St Albans & Harpenden PCT both had a significantly lower ratio of stomach cancer mortality than England For More Information: Please contact David Edwards, Public Health Intelligence Specialist, PHIU (david.edwards@phi-bedsherts.nhs.uk) Page 2 Source: National Statistics, Compendium of Clinical and Health Indicators 2003 (Final Release 04/05) Mortality From Stomach Cancer (SMR with 95% CI), 2001-2003 Pooled, All Ages 0 ...

U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health What You Need To Know About TM Stomach Cancer National Cancer Institute What You Need To Know About Index Page 2 This booklet is about stomach cancer . The Cancer Information Service can help you learn more about this disease. The staff can talk with you in English or Spanish. The number is 1–800–4– CANCER (1–800–422–6237). The number for callers with TTY equipment is 1–800–332–8615. Your call is free. Este folleto es acerca del cáncer de estómago. Llame al Servicio de Información sobre el Cáncer para saber más sobre esta enfermedad. Este servicio tiene personal que habla español. El número a llamar es el 1–800–4– CANCER (1–800–422–6237). Personas con ...

Incidence and Mortality Rate Trends Stomach cancer is the second leading cause of cancer -related death throughout the world. However, incidence and mortality rates for stomach cancer are lower in the United States and have declined over the past several years. The impact of stomach cancer varies by racial/ ethnic group. Asian or Pacific Islanders are the most vulnerable, followed byAfricanAmericans, Hispanics, American Indians/Alaskan Natives, and Whites. Men have higher stomach cancer incidence and mortality rates than women. Source for incidence and mortality data: Surveillance, Epidemiology, and End Results (SEER) Program and the National Center for Health Statistics. Additional statistics and charts available at: http://seer. cancer .gov/ U.S. Stomach Cancer Mortality U.S. Stomach Cancer Incidence Trends in ...

2004/8/24 WCE2005 Bangkok 1 Risk factors for stomach and lung cancer : a cohort study in Higashi-Yamanashi County, Japan Michiko KUROSAWA, Yutaka INABA, Tsuyoshi MATSUBA (Dept. of Epidemiology & Environmental health, Juntendo Univ. School of Medicine) Shogo KIKUCHI (Dept. of Public Health, Aichi medical Univ. School of Medicine) Hirofumi TAKAGI (School of Health Sciences, Faculty of Med., Niigata University) Toshiya SATO (Dept. of Biostatistics, Kyoto Univ. School of Public Health) Toshihiko AGATA (Dept. of Public Health, Jikei Univ. School of Med.) Page 2 2004/8/24 WCE2005 Bangkok 2 Objective To analyze the relationships between life-style factors and risk of stomach and lung cancer death. Page 3 2004/8/24 WCE2005 Bangkok ...

National Cancer Institute SEER Program 112 STOMACH S tomach cancer was the most common form of cancer in the world in the 1970s and early 1980s, and is probably now only surpassed by lung cancer . Stomach cancer incidence rates show substantial variation internationally. Rates are highest in Japan and eastern Asia, but other areas of the world have high stomach cancer incidence rates including eastern Europe and parts of Latin America. Incidence rates are generally lower in western Europe and the United States. Stomach cancer incidence and mortality rates have been declining for several decades in most areas of the world. For one subsite of the stomach , the cardia, incidence rates appear to be increasing, particularly among white men. Stomach cancer incidence rates for the racial/ethnic populations in the SEER ...

A209: Stomach cancer tissues For research use only (formalin fixed) Specifications: • No. of cases: 50 • Tissue type: Stomach cancer tissues • No. of spots: 2 spots from each cancer case (100 spots) 4 non-neoplastic spots (4 spots) • Total spots: 104 • Corresponding normal tissues with cancers: No • Diameter: 1. 0 mm Documents : • Product specification: layout, summary of tissue spots • H&E stained images • Detailed pathological information Layout: Page 2 A209: Stomach cancer tissues Summary of tissue spots For research use only (formalin fixed) No. Sex Age Specimen Key Word Grade Stage 1 1(NormalQ C) M 43 stomach signet ring cell carcinoma 2 2(NormalQ C) M ...

MORTALITY FROM STOMACH CANCER BY PCT Notes: Mortality from stomach cancer (ICD10 C16): Data are based on the original underlying cause of death. Data are based on ONS population estimates (February 2005 release). Highlights: Bedfordshire Heartlands PCT and St Albans & Harpenden PCT both had a significantly lower ratio of stomach cancer mortality than England For More Information: Please contact David Edwards, Cancer Lead, Public Health Intelligence Specialist, PHIU (david.edwards@phi-bedsherts.nhs.uk) Page 2 Source: National Statistics, Compendium of Clinical and Health Indicators (Released 04/05) Mortality from Stomach Cancer (SMR with 95% CI), 2001-2003 Pooled, All Ages 0 20 40 60 80 100 120 140 160 Bedford PCT Bedfordshire Heartlands PCT Luton PCT Dacorum PCT Watford ...

1672 Main St. Ste. E #264 • Ramona, CA 92065 • Tel: 760.789.8928 • Fax: 760.789.8929 • Toll Free: 800.475.1955 • www.proteinbiotechnologies.com HUMAN STOMACH CANCER TISSUE MICROARRAY Catalog Number: TMA-010 Each core from each tissue represents one specimen selected and pathologically confirmed. Normal matched or unmatched stomach tissue is provided for comparison to the cancer tissue. Cases : 40 Cores : 80 Diameter : 1.5 mm Thickness: 5 µm Standard IHC: Cytokeratin confirmed Layout : 8 x 10 1 2 3 4 5 6 7 8 9 10 A 1 2 3 4 5 6 7 8 9 10 B 11 12 13 14 15 16 17 18 19 20 C 21 22 23 24 25 26 27 28 29 30 ...

TRENDS IN MORTALITY FROM STOMACH CANCER (ICD10 C16, ICD9 151 adjusted): INDIRECTLY STANDARDISED RATIOS (SMR), 1993 TO 2001 ANNUALLY, ALL AGES (Standard rates are age-specific mortality rates in 2001) SMRs for PCTs cannot be calculated for 1993 to 1997 as denominator data are not available Figures for observed numbers (males and persons only) have been adjusted for 1993-1998 and 2000 to take into account ICD-10 MALES FEMALES PERSONS 1998 1999 2000 2001 1998 1999 2000 2001 1998 1999 2000 2001 ENGLAND AND WALES SMR 120 115 106 100 117 109 101 100 119 112 104 100 OBS 4014 3886 3645 3490 2496 2309 2156 2158 6510 6195 5801 5648 ENGLAND SMR 118 113 105 99 116 107 99 99 117 111 103 ...

Center for Environmental Health Studies (617) 482-9485 44 Farnsworth Street, Boston, MA 02210 http://www.jsi.com Stomach Cancer and Exposure to Ionizing Radiation 1 Stomach Cancer and Exposure to Ionizing Radiation Summary: Moderately strong evidence has been recorded of a possible connection between stomach cancer and exposure to ionizing radiation. This evidence is based upon studies of nuclear workers exposed to ionizing radiation. These findings are consistent with the National Research Council’s determination that the stomach is sensitive to ionizing radiation. Stomach cancer is designated as a “specified” cancer under the Energy Employees Occupational Illness Compensation Program Act. Historically, stomach cancer incidence and mortality have been very low for Los Alamos County. Incidence and mortality in Rio Arriba County have been very high among ...

ancer dvances C A ancer dvances C A NEWS FROM THE 2005 ASCO ANNUAL MEETING Lymph nodes are tiny, bean- shaped glands that help fight infec- tion. When cancer cells start to spread to other parts of the body, they first go to the lymph nodes. During stomach cancer surgery, doctors remove a number of these lymph nodes and examine them for evidence of cancer . The more lymph nodes that are removed and examined, the more certain a doc- tor can be about how far the can- cer has spread. This information helps determine the stage (descrip- tion) of the cancer and guides treat- ment decisions. In 1997, the American Joint Committee on Cancer (AJCC) determined that 15 lymph nodes should be removed and assessed in people having stomach cancer surgery. In this study, investigators ana- lyzed 11,602 ...

CASE NOTE 02HDC08972: Missed early diagnosis of stomach cancer Right to services of an appropriate standard – Reasonable care and skill – General practitioner – Missed diagnosis – Cancer – Stomach – Peptic ulcer disease – Investigations – Gastroscopy – Right 4 A complaint was made by Mrs A that her GP did not provide services of an appropriate standard. The complaint was on the basis that (1) after a normal barium meal investigation the GP did not order any further investigations, although Mrs A continued to complain of abdominal pain and vomiting; (2) that the GP did not refer her for specialist assessment when her symptoms continued and her general health deteriorated; and (3) the GP did not discuss with her the option of gastroscopy. The facts were that between March 1998 and 2000 Mrs A consulted the GP on a number of occasions relating to gastrointestinal symptoms. On two occasions, ...

Detection of cancer cells in peripheral blood of stomach cancer patients using RT–PCR amplification of tumour-specific mRNAs J-H. SHIN*à, J. CHUNG*à, H-O. KIM , Y-H. KIM , Y-M. HUR*, J-H. RHIM, H-K. CHUNGà, S-C. PARKà, J-G. PARK* & H-K. YANG *National Cancer Center, Koyang, Kyunggi, Korea; Department of Surgery & Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea; and à Department of Biochemistry & Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea INTRODUCTION Stomach cancer is one of the most prevalent cancer types in the world today. The 5-year survival rate remains poor for this type of cancer , and only two survival-influencing factors, the depth of invasion and the presence of regional lymph node involvement, are commonly used in prognosis. 1, 2 ...

!"# !$%&'%(!)* #+%,!-./)01%2!34).3#+%5$6.1/ '%7! 6.3!1 Waikato District Health Board Stomach cancer Mortality (0-74) Introduction Rationale Methodology Data Coverage Period Method Description Interpretation International Classification of Disease Codes (ICD Version 9 & 10) ICD 9 ICD 10 Findings 1 Ethnicity Volume Trend 2 Age Gender Volume Proportion Profile 3 Age Ethnicity Volume Profile - All years 4 Age Ethnicity Volume Proportion Profile (All Years) 5 Age Standardised Trend - Waikato District Health Board versus NZ rate per 10,000 persons 6 Maori Age Standardised Trend - Waikato District Health Board versus NZ rate per 10,000 persons 7 Paciifc People Age Standardised Trend - Waikato District Health Board versus NZ rate per 10,000 persons 8 Other Ethnicity Age Standardised Trend - Waikato District Health Board ...

!"# !$%&'%(!)* #+%,!-./)01%2!34).3#+%5$6.1/ '%7! 6.3!1 Waikato District Health Board Stomach cancer Mortality Introduction Rationale Methodology Data Coverage Period Method Description Interpretation International Classification of Disease Codes (ICD Version 9 & 10) ICD 9 ICD 10 Findings 1 Ethnicity Volume Trend 2 Age Gender Volume Proportion Profile 3 Age Ethnicity Volume Profile - All years 4 Age Ethnicity Volume Proportion Profile (All Years) 5 Age Standardised Trend - Waikato District Health Board versus NZ rate per 10,000 persons 6 Maori Age Standardised Trend - Waikato District Health Board versus NZ rate per 10,000 persons 7 Paciifc People Age Standardised Trend - Waikato District Health Board versus NZ rate per 10,000 persons 8 Other Ethnicity Age Standardised Trend - Waikato District Health Board versus ...

Cancer Incidence by Remoteness Category in Queensland Cancer of the Stomach 0 3 6 9 12 15 18 21 0 3 6 9 12 15 18 21 Male Female Rate per 100,000 population Rate per 100,000 population Avg No. Avg No. per Year per Year Incidence of Cancer of the Stomach , by ARIA+ Category and Sex, Queensland, Five Year Average, 1998 to 2002 15.6 119 6.1 60 Major City ARIAplus Category 13.4 61 6.4 34 Inner Regional 13.8 35 6.5 18 Outer Regional 9.5 2 1.8 0 Remote 9.7 2 5.7 1 Very remote Note: Rates are age standardised to the Australian population as at 30 June 2001. Numbers and ...

Cancer Mortality by Remoteness Category in Queensland Cancer of the Stomach 0 3 6 9 12 15 0 3 6 9 12 15 Male Female Rate per 100,000 population Rate per 100,000 population Avg No. Avg No. per Year per Year Mortality of Cancer of the Stomach , by ARIA+ Category and Sex, Queensland, Five Year Average, 1998 to 2002 10.8 80 3.5 35 Major City ARIAplus Category 9.9 44 3.6 19 Inner Regional 11.1 27 4.5 12 Outer Regional 6.0 1 2.7 1 Remote 6.2 1 2.8 0 Very remote Note: Rates are age standardised to the Australian population as at 30 June 2001. Numbers and rates are averaged over five ...

Age-specific Cancer Mortality in Queensland Cancer of the Stomach Rate per 100,000 population Mortality of Cancer of the Stomach , by Age Group and Sex, Queensland, Five Year Average, 1998 to 2002 Male Female 0 25 50 75 100 125 150 Age group (years) 0 5 10 15 20 25 30 35 40 45 50 55 60 65 70 75 80 85+ Note: Age-specific rates are averaged over the five years, and based on age at time of diagnosis. Only the first year of each 5-year age group is displayed on the x-axis. Cancer of the Stomach is defined by the ICD-0-2 codes of C16 Source: Queensland Cancer Registry, Queensland Health and Queensland Cancer Fund. Generated by Epidemiology Services Unit, Queensland Health For more information: Health Status ...

Age-specific Cancer Incidence in Queensland Cancer of the Stomach Rate per 100,000 population Incidence of Cancer of the Stomach , by Age Group and Sex, Queensland, Five Year Average, 1998 to 2002 Male Female 0 25 50 75 100 125 150 Age group (years) 0 5 10 15 20 25 30 35 40 45 50 55 60 65 70 75 80 85+ Note: Age-specific rates are averaged over the five years, and based on age at time of diagnosis. Only the first year of each 5-year age group is displayed on the x-axis. Cancer of the Stomach is defined by the ICD-0-2 codes of C16 Source: Queensland Cancer Registry, Queensland Health and Queensland Cancer Fund. Generated by Epidemiology Services Unit, Queensland Health For more information: Health Status ...

Trends in Cancer Incidence in Queensland Cancer of the Stomach Rate per 100,000 population Incidence of Cancer of the Stomach , by Sex, Queensland, 1982 to 2002 Male Female 0 5 10 15 20 25 30 Year 1982 1984 1986 1988 1990 1992 1994 1996 1998 2000 2002 Note: Rates are age standardised to the Australian population as at 30 June 2001. Data are reported by year of diagnosis. Cancer of the Stomach is defined by the ICD-0-2 codes of C16 Source: Queensland Cancer Registry, Queensland Health and Queensland Cancer Fund. Generated by Epidemiology Services Unit, Queensland Health For more information: Health Status Indicators for Queensland Queensland Health Cancer Publications (http://www.health.qld.gov.au/hic/default.asp) Queensland ...

Cancer Incidence by Proportion Indigenous Population in Queensland Cancer of the Stomach 0 3 6 9 12 15 18 0 3 6 9 12 15 18 Male Female Rate per 100,000 population Rate per 100,000 population Avg No. Avg No. per Year per Year Incidence of Cancer of the Stomach , by Indigenous Proportion and Sex, Queensland, Five Year Average, 1998 to 2002 14.5 198 6.3 105 <5% Indigenous Proportion Indigenous Population 14.5 21 5.1 7 At least 5% Indigenous Note: Rates are age standardised to the Australian population as at 30 June 2001. Numbers and rates are averaged over five years, and based on place of usual residence at time of diagnosis. The range shown by the orange line corresponds ...

Trends in Cancer Mortality in Queensland Cancer of the Stomach Rate per 100,000 population Mortality of Cancer of the Stomach , by Sex, Queensland, 1982 to 2002 Male Female 0 3 6 9 12 15 18 21 Year 1982 1984 1986 1988 1990 1992 1994 1996 1998 2000 2002 Note: Rates are age standardised to the Australian population as at 30 June 2001. Data are reported by year of diagnosis. Cancer of the Stomach is defined by the ICD-0-2 codes of C16 Source: Queensland Cancer Registry, Queensland Health and Queensland Cancer Fund. Generated by Epidemiology Services Unit, Queensland Health For more information: Health Status Indicators for Queensland Queensland Health Cancer Publications (http://www.health.qld.gov.au/hic/default.asp) ...