AllDocs -> cancers

Support Care Cancer (2004) 12:476–486 DOI 10.1007/s00520-004-0646-x REVIEW ARTI CLE J. Fleer H. J. Hoekstra D. Th. Sleijfer J. E. H. M. Hoekstra-Weebers Quality of life of survivors of testicular germ cell cancer : a review of the literature Received: 14 January 2004 Accepted: 20 April 2004 Published online: 4 June 2004 Springer-Verlag 2004 This research was supported by a grant from the Dutch Cancer Society, no. RUG 99–2130 J. Fleer · H. J. Hoekstra ( ) ) Department of Surgical Oncology, University Hospital Groningen, PO Box 30.001, 9700 RB Groningen, The Netherlands e-mail: h.j.hoekstra@chir.azg.nl Tel.: +31-50-3612303 Fax: +31-50-3614873 D. T. Sleijfer Department of Medical Oncology, University Hospital Groningen, Groningen, The Netherlands J. E. H. M. Hoekstra-Weebers Department ...

454 Sexual Functioning after Treatment for Testicular Cancer Comparison of Treatment Modalities BACKGROUND. This retrospective study evaluates changes in sexual functioning Grieteke Jonker-Pool, M.A. 1,2 Jean P. van Basten, M.D. 1 after treatment for testicular cancer and investigates whether there is a relationship with different treatment modalities. Harald J. Hoekstra, M.D., Ph.D. 1 Mels F. van Driel, M.D., Ph.D. 3 METHODS. A self-reported questionnaire was sent to 337 men who had been treated for testicular cancer at the University Hospital Groningen between 1977 and 1994. Dirk Th. Sleijfer, M.D., Ph.D. 4 Heimen Schraffordt Koops, M.D., Ph.D. 1 Medical information was ...

Testicular Cancer Fact Sheet Testicular cancer is one of the more rare forms of cancer . For every 100,000 men, only 6 are found to have testicular cancer every year. Young men are more likely to develop testicular cancer , with about half of all new cases under the age of 33 years. Risk factors for testicular cancer include: o Age (from 15 to 40) o Being born with an undescended testicle o A family history of testicular cancer o A history of testicular cancer in the other testicle Since none of the current known risks for testicular cancer can be prevented, the best protection is awareness of risks, signs and symptoms; and early detection, and prompt treatment. The earlier you find testicular cancer the easier it is to treat. ? When found and treated early, testicular cancer is treatable and curable ...

Center for Environmental Health Studies (617) 482-9485 44 Farnsworth Street, Boston, MA 02210 http://www.jsi.com Testicular Cancer and Exposure to Ionizing Radiation 1 Testicular Cancer and Exposure to Ionizing Radiation Summary: Evidence varies on whether there may be an connection between testicular cancer and exposure to ionizing radiation. This connection is supported by some evidence from studies of nuclear workers in England who have been exposed to ionizing radiation. The National Research Council’s, on the other hand, has determined that the testis are relatively insensitive to ionizing radiation. Testicular cancer is not designated as a “specified” cancer under the Energy Employees Occupational Illness Compensation Program Act. Historically, testicular cancer incidence has been very high for Los Alamos County while mortality was very low compared ...

HEALTH Budget &Control Board Budget &Control Board Budget &Control Board Budget &Control Board Budget &Control Board Budget &Control Board Budget &Control Board Budget &Control Board Budget &Control Board Budget &Control Board Budget &Control Board Budget &Control Board Budget &Control Board Budget &Control Board Budget &Control Board Budget &Control Board Budget &Control Board Budget &Control Board Budget &Control Board Budget &Control Board Budget &Control Board Budget &Control Board Budget &Control Board Budget &Control Board Budget &Control Board Budget &Control Board STATE HEALTH PLANPREVENTIONPARTNERS South Carolina Budget and Control Board Employee Insurance Program April 2003 What is Testicular Cancer ? Testicular cancer is cancer that develops ...

Testicular Cancer In 2005, an estimated 8,010 males will be diagnosed with testicular cancer . When found early, testicular cancer is one of the most treatable forms of cancer , with an overall cure rate above 90 percent. PREVENTION • Talk to your health care professional about screening. RISK • All men • Men with a history of cryptorchidism — testicle(s) that have not descended • Men with a personal or family history of testicular cancer • Caucasian men are at higher risk SYMPTOMS Most testicular cancer can be found at an early stage. Some of the symptoms that may appear include: • A lump on either testicle • Enlargement of either testicle • Heaviness or aching in the lower abdomen or scrotum • Pain or discomfort in a testicle or in the scrotum • A collection of fluid in the scrotum • Breast growth or tenderness EARLY DETECTION ...

SEARCH advanced search help site index 10 May 2005 Journal Home Current issue Previous issue Advance Online Publication Archive Author index Keyword index Aims & scope Editors & editorial board Contacts For authors Submitting to BJC Copyright agreement Services Receive Table of Contents by email Online sample copy FREE Order sample copy Recommend to your library Prices Epidemiology British Journal of Cancer (2005) 92, 1785-1786. doi:10.1038/sj.bjc.6602539 Published online 12 April 2005 Serum cholesterol and testicular cancer incidence in 45 000 men followed for 25 years A-B Wiréhn 1 , S Törnberg 2 and J Carstensen 1 1 Department of Health and Society, ...

Request for Applications Illinois Prostate and Testicular Cancer Education and Awareness Program July 1, 2005 - June 30, 2006 Illinois Department of Public Health Office of Health Promotion Men’s Health Program 535 West Jefferson, 2 nd Floor Springfield, Illinois 62761 Phone: 217-782-3300 Fax: 217-782-1235 Page 2 Illinois Prostate and Testicular Cancer Education and Awareness Program Page 2 Illinois Department of Public Health Office of Health Promotion Illinois Prostate and Testicular Cancer Education and Awareness Program March 31, 2005 Request for Application for State Fiscal Year 2006 Application Package Contents: • Background and Purpose • General Information • Instructions for Application • Grant Application ...

CODE: PIE CCO Formulary Revised November, 2004 A REGIMEN NAME CISPLATIN-IFOSFAMIDE-ETOPOSIDE (PIE) Chemotherapy Cancer Testicular Cancer - Salvage Therapy Curative Intent Regimen Category Core: Standard therapy; a regimen widely used by most Regional Cancer Centres Rationale and Indication First or second line treatment of testicular cancer with curative intent B DRUG REGIMEN CISPLATIN (Round to nearest 1mg) 20mg/m² IV Days 1 to 5 IFOSFAMIDE (Maximum dose = 1.75g – Round to nearest 25mg) 1200mg/m² IV Days 1 to 5 ETOPOSIDE (Round to nearest 10mg) 75-100mg/m² IV Days 1 to 5 MESNA (Round to nearest 0.3mg) 120mg/m² IV bolus Prior to Ifosfamide on Day 1 MESNA ...

CODE: VIP CCO Formulary Revised November, 2004 A REGIMEN NAME VINBLASTINE-IFOSFAMIDE-CISPLATIN (VIP) Chemotherapy Cancer Testicular Cancer - Salvage Therapy Curative Intent Regimen Category Core: Standard therapy; a regimen widely used by most Regional Cancer Centres Rationale and Indication First or second line treatment of testicular cancer with curative intent B DRUG REGIMEN CISPLATIN (Round to nearest 1mg) 20mg/m² IV Daily for 5 days - day 1 IFOSFAMIDE (Maximum dose = 1.75g - Round to nearest 25mg) 1200mg/m² IV Daily for 5 days - day 1 VINBLASTINE (Round to nearest 1mg) 0.11mg/Kg IV Days 1 & 2 MESNA (Round to nearest 0.3mg) 120mg/m² IV bolus Prior to Ifosfamide On ...

research for a cure laboratory without walls National Foundation for Cancer Research Cancer FAQs about testicular cancer Frequently Asked Questions about common cancers. Page 2 Cancer FAQs What are the different types of testicular cancer ? There are many different forms of testicular cancer , but most types begin in immature cells called germ cells, which develop into sperm. The two main types of germ cell tumors are seminomas and nonseminomas. Many testicular tumors have features of both forms. The various types of testicular cancers differ in their prognosis (survival outlook) and in the ways they are treated. Seminomas are the most curable of testicular cancers, as they grow very slowly and do not spread to other parts of the body. They account for about 30 percent of all testicular cancers and are typically ...

Testicular Cancer Quote Request Name _ Sex M F Date of Birth __ Height Weight Smoker? Y N State Coverage Desired? _ Amount __ Plan Desired? __ Have you ever been Rated or Declined for insurance? If YES Complete details please _ When were you first told that you had Testicular Cancer ? __ How was the cancer treated? (Please circle all that apply and give dates of treatment ) Surgery Chemotherapy Radiation Other What was the size of the Tumor? __ What was the Stage of the Tumor? _ Has the cancer spread beyond the original site? Y N Were any Lymph Nodes involved? Y N If YES, Complete Details please __ Are you on any Medication or Radiation Treatment now? Y N When was the last date of Medication or Radiation Treatment? Is there any ...

Targeted destruction of prostate, breast, ovarian, and testicular cancer cells through their LH/CG receptors William Hansel and Carola Leuschner Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA, 70808 In a series of in vitro and in vivo experiments involving 1630 nude mice, the concept has been established that prostate, breast, ovarian and testicular cancer cells that express LH/CG receptors can be targeted and destroyed by compounds consisting of a lytic peptide moiety and a 15-amino acid segment of the beta chain of CG. LH/CG receptor capacity was closely correlated with the toxicity of the targeting lytic peptide-CG conjugates. Data obtained in vitro established the validity of this concept, showed the strong specificities of the Hecate-ßCG, and Phor14 and Phor21-ßCG conjugates in killing cells that express functional LH/CG receptors and proved that the LH/CG receptor ...

Social Science & Medicine 58 (2004) 1597–1607 (Dis)embodying gender and sexuality in testicular cancer Maria Gurevich a, *, Scott Bishop b , Jo Bower c , Monika Malka d , Joyce Nyhof-Young e a Department of Psychology, Ryerson University and Psychosocial Oncology and Palliative Care Program, Princess Margaret Hospital, University Health Network, 350 Victoria Street, Toronto, Ont., Canada M5B 2K3 b Psychological Trauma Program, Centre for Addiction and Mental Health, and Department of Psychiatry, University of Toronto, Canada c Communications and Psychology Research Consulting, Canada d Circle of Care and Jewish Hospice Programs, Canada e Department of Radiation Oncology, University of Toronto, Princess Margaret Hospital, University Health Network, Canada ...

Is Testicular Cancer Related to Gulf War Deployment? Evidence from a Pilot Population-Based Study of Gulf War Era Veterans and Cancer Registries Contributors: Paul H. Levine, MD; Heather A. Young, PhD; Samuel J. Simmens, PhD; Danielle Rentz, MPH; Vincent E Kofie, PhD; Clare M. Mahan, PhD; Han K. Kang, DPH Military Medicine , 170, 2:149, 2005 Abstract The possible relationship between military deployment and the subsequent increase in cancer rates has been prominent since the Vietnam War. The objective of this study was to investigate whether any form of cancer was increased among veterans deployed to the Persian Gulf in the 1991 conflict. This study matched data from central cancer registries in the District of Columbia and New Jersey with the records of the 1.4 million Gulf War era veterans; i.e., 621,902 veterans who arrived in the Persian Gulf before March 1, 1991, ...

Summary of Recommendation The U.S. Preventive Services Task Force (USPSTF) recommends against routine screening for testicular cancer in asymptomatic adolescent and adult males. D recommendation. The USPSTF found no new evidence that screening with clinical examination or testicular self-examination is effective in reducing mortality from testicular cancer . Even in the absence of screening, the current treatment interventions provide very favorable health outcomes. Given the low prevalence of testicular cancer , limited accuracy of screening tests, and no evidence for the incremental benefits of screening, the USPSTF concluded that the harms of screening exceed any potential benefits. Clinical Considerations • The low incidence of testicular cancer and favorable outcomes in the absence of screening make it unlikely that clinical ...

Methods We searched MEDLINE ® for articles focusing on meta-analysis, systematic reviews, randomized controlled trials (RCTs), and controlled trials or well-designed cohort or case control studies reporting demonstrable health outcomes (morbidity and/or mortality) in humans that were published in English between the years 1994 and 2001. The Cochrane Library and National Guideline Clearinghouse were also searched for pertinent articles or recommendations. The search strategy employed for MEDLINE combined the exploded MeSH heading of Testicular Neoplasm with Germinoma (limited to male) and crossed the result with Mass Screening, yielding 19 articles. These articles were further limited to RCTs by the exploded headings—randomized controlled trial/single-blind method/double-blind method/random allocation, for which no articles were identified. Limiting to reviews ...

384 RESIDUAL MASS IN NON-SEMINOMATOUS TESTICULAR CANCER Clinical Urology International Braz J Urol Official Journal of the Brazilian Society of Urology Vol. 30 (5): 384-388, September - October, 2004 POST-CHEMOTHERAPY RESIDUAL MASS IN NON-SEMINOMATOUS TESTICULAR CANCER . THE ROLE OF RETROPERITONEAL LYMPH NODE DISSECTION SALWAEL SAYED, JOÃO P. S. GRANDO, SILVIO H. M. DE ALMEIDA, NICOLA MORTATI NETO, HORÁCIO A. MOREIRA Department of Urology, Cancer Institute of Londrina, Londrina, Parana, Brazil ABSTRACT Purpose: to determine the role of RPLND for residual masses following chemotherapy in patients with non-seminomatous germ cell tumors (NSGCT) stage T1N2 and T1N3 (IIB and IIC). Materials and Methods: We have preformed retrospective analysis of 11 patients who under- went RPLND for residual masses following chemotherapy in an oncologic reference center ...

Swedish & Norwegian Testicular Cancer Project —SWENOTECA“ & Oncologic Center, Lund, Sweden SWENOTECA VI A revised continuation of SWENOTECA III A cancer care program Non-Seminomatous Germ Cell Testicular Cancer (NSGCT) Clinical Stage I (CS1) September 2004 www.ocsyd.l u.se Page 2 SWENOTECA VI 2 Drawing on front page: Eva Henriksson ISBN 91-85738-64-6 Lund 2004 Page 3 SWENOTECA VI 3 Contents Flow sheet..5 1. Background7 1.1 General information..7 1.2 International guidelines for the treatment of CS1..8 1.3 Recent experience from the Swedish-Norwegian Testicular Cancer (SWENOTECA) group8 2. Purpose of the SWENOTECA VI treatment program for patients with NSGCT in CS1 .11 3. ...

What is testicular cancer ? Although relatively rare, testicular cancer is the most common cancer in males age 15-40 causing about 400 deaths each year. Studies have shown that many men may delay seeking medical attention for as long as three to six months after detecting a testicular abnormality. However, as with many cancers early detection and prompt treatment are key in improving the outcome. Since early detection and treatment are important, properly perform a monthly testicular self- examination (TSE) and discuss any abnormal or unusual findings with your health care provider promptly. Doing the exam regularly once a month may allow you to detect any changes that may have occurred. Risk factors for testicular cancer The risk for developing testicular cancer is increased in men whose testicles did not descend from the body into the scrotum ...

ELECTRONIC LETTER Y chromosome haplotypes and testicular cancer in the English population L Quintana-Murci, M E Weale, M G Thomas, E Erdei, N Bradman, J H Shanks, C Krausz, K McElreavey .. J Med Genet 2003;40:e20(http://www.jmedgenet.com/cgi/content/full/40/3/e20) T esticular cancer (TC) affects 1 in 500 males and is the most common malignancy among young men in western Euro- pean populations; for example, in Denmark 1% of all men now develop TC. 1–4 More than 97% of testes cancers are germ cell tumours. 4 Although the aetiology of these malignancies is unknown, there is accumulating evidence of an intrauterine stage of TC development that may involve both environmental and genetic factors acting on the primordial gonocyte. 4 Although many tumour suppressor genes have been studied, there is little evidence supporting ...

JCI 00 M 4/2004 Material for this fact sheet was adapted from the American Cancer Society’s Detailed Guide: Testicular Cancer web page, last revised 6/9/03. Testing can save your life Testicular cancer is one of the most curable forms of cancer , especially when detected and treated early. Testing can help you check for testicular cancer before there are symptoms. The Karmanos Cancer Institute recommends the following testing for testicular cancer : • monthly testicular self-examination for all men, especially if they have any of the known risk factors Regular self-exams will help you become familiar with what is normal and what is different for you. Always tell your doctor about any lumps or changes. Lower the risk for testicular cancer Here are some things you can do to reduce your risk of testicular cancer : • find out ...

UPDATE MARCH 2004 European Association of Urology GUIDELINES ON TESTICULAR CANCER M.P. Laguna (Chairperson), O. Klepp, A. Horwich, F. Algaba, C. Bokemeyer, G. Pizzocaro, G. Cohn-Cedemark, P. Albers Page 2 TABLE OF CONTENTS PAGE 1 BACKGROUND 4 1.1 Methods 4 2 PATHOLOGY AND NATURAL HISTORY 4 3 DIAGNOSIS 5 3.1 Clinical examination 5 3.2 Imaging of the Testis 5 3.3 Serum Tumor Markers at diagnostic 5 3.4 Inguinal exploration and orchiectomy 6 3.5 Organ sparing surgery 6 3.6 Pathological examination of the testis 6 3.7 Diagnosis of Carcinoma in situ (Tin) 6 3.8 Screening 7 4 STAGING 7 4.1 Diagnostic tools 7 4.2 Serum tumour markers. Postorchiectomy ...

04/060 For immediate release: Friday 25 June 2004 RAISING MONEY AND RAISING AWARENESS FOR TESTICULAR CANCER Tim Coupland (34) was diagnosed with testicular cancer in June 2003, now, just over a year later, following surgery and treatment he is undertaking a 45 mile sponsored bike ride between the two hospitals where he received his treatment . At 10.30 on Sunday 27 th June, Tim and more than 20 other sponsored cyclists will be setting off from Lincoln Country Hospital and travelling via Wragby and Horncastle to Pilgrim Hospital, Boston. Tim, who has already raised £2,000 with a sponsored head shave is hoping to equal his previous sum if not exceed it. The money raised will benefit the urology ward and the Scanner appeal at Pilgrim Hospital and the Oncology dept and Wragby Ward at Lincoln County Hospital. It is also hoped intended that Macmillan Nurses will benefit – ...

26 Testicular cancer unravelling the genetics of a molecular jigsaw Robert Huddart MBBS PhD MRCP FRCR Clinical Senior Lecturer and Honorary Consultant in Radiotherapy A disease with an underrated importance T esticular cancer is an intriguing and sometimes perplexing illness with an importance that belies its relative infrequency (approximately 1500 cases per year in the United Kingdom). Its importance is partly due to its unusual age distribution: with a peak age of onset of 25-30, as such making it the most common male cancer in the 15-40 age group. Furthermore, in the United Kingdom we are in the middle of an epidemic of testicular cancer . Indeed, the incidence has doubled in the last 20-30 years and is rising by 10-20% every 5 years. More importantly, testicular cancer is unique among solid adult tumours in that the majority of cases ...

TROUBLE WITH YOUR WATERWORKS ? How to carry out a testicular self-examination You should perform these easy steps regularly. A thorough examination may be easier after a warm bath or shower as the scrotal skin relaxes. 1 Most lumps found on the testicles are benign but any changes in size, shape or weight should be checked by your GP. 2 Support the scrotal sac in the palm of your hand and become familiar with the size and weight of each testicle. 3 Examine each testicle by rolling it between your fingers and thumb. Press gently to feel for lumps, swellings, or changes in firmness. 4 Remember each testicle has a tubular structure at the top which carries sperm to the penis. Don’t panic if you feel ...

Request for Applications Illinois Prostate and Testicular Cancer Education and Awareness Program July 1, 2004 - June 30, 2005 Illinois Department of Public Health Office of Health Promotion Men’s Health Program 535 West Jefferson, 2 nd Floor Springfield, Illinois 62761 Phone: 217-782-3300 Fax: 217-782-1235 Page 2 Illinois Prostate and Testicular Cancer Program Page 2 Illinois Department of Public Health Office of Health Promotion Illinois Prostate and Testicular Cancer Education and Awareness Program May 1, 2004 Request for Application for State Fiscal Year 2005 Application Package Contents: - Background and Purpose - General Information - Instructions for Application - Grant ...

This booklet has been written to help you understand testicular cancer . It has been prepared and checked by cancer doctors, other relevant specialists, nurses and patients. The information contained in this booklet represents an agreed view on this cancer , its diagnosis and management, and the key aspects of living with it. If you are a patient, your doctor or nurse may wish to go through the booklet with you and mark sections that are particularly important for you. You can make a note below of the contact names and information that you may need quickly. testicular cancer Understanding Specialist nurse/contact names Hospital Phone Treatments Family doctor Surgery address Phone Review dates If you like, you can also add: Your name Address Page 2 ¦ Understanding testicular cancer ...

Abstract. The metabolism of arachidonic acid by either the cyclooxygenase (COX) or lipoxygenase (LOX) pathway generates eicosanoids, which have been implicated in the pathogenesis of a variety of human diseases, including cancer . They are now believed to play important roles in tumor promotion, progression, and metastasis, and the involvement of LOX expression and function in tumor growth and metastasis has been reported in human tumor cell lines. Expressions of 5-LOX and 12-LOX in human testicular cancer (TC), and normal testis (NT) tissues were examined, as well as effects of their inhibitors on cell proliferation in TC cell line. Expressions of 5-LOX and 12-LOX were detected by immuno- histochemistry. Effects of LOX inhibitors on TC cell growth were examined by MTT assay. While 5-LOX and 12-LOX expressions were slightly detected in NT tissues, expressions of 5-LOX and 12-LOX were significant ...

53 NEEDS MEN’S WELLNESS Cancer of the testicles most often develops in young men between the ages of 15 to 34. While cancer happening in such young men might seem fairly ominous, testicular cancer is almost always curable if found early. Even when the cancer has spread to other parts of the body (or metastasized) treatment can still be fairly effective. Men frequently find the presence of testicular cancer themselves, either by chance or during a testicular self- examination (TSE). After ruling out the possibility of an infection or other health problems that can also cause these symptoms, cancer is generally suspected. As in most cancers, including testicular cancer , a biopsy (the removal and examination of tissue, cells, or fluids from the living body) is needed to make a definite diagnosis. However, in the case ...