[181]
Chapter 5 Residual mass histology in testicular germ cell cancer ...
[362,8 KB]
From [ep.eur.nl] Last viewed: 07.09.2006
Chapter 5
Residual mass histology in testicular germ cell cancer :
development and validation of a clinical prediction model
Abstract
After chemotherapy for metastatic non-seminomatous testicular germ cell cancer , surgical
resection is a generally accepted treatment to remove remnants of the initial metastases,
since residual tumour may still be present (mature teratoma or viable cancer cells). In this
paper, we review the development and external validation of a logistic regression model to
predict the absence of residual tumour. Three sources of information were used. A
quantitative review identified six relevant predictors from 19 published studies (996
resections). Second, a development data set included individual data of 544 patients from six
centres. This data set was used to assess the predictive relationships of five continuous
predictors, which resulted in dichotomization ...
[182]
Contralateral Testicular Cancer in spite of TIN-Negative Double ...
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[183]
Abnormal ultrasonic pattern in contralateral testes in patients ...
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[184]
Progress in treatment of testicular cancer
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[185]
Automated image analysis DNA cytometry in testicular cancer
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[186]
Fertility patterns prior to testicular cancer diagnosis
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[187]
Chromosomal damage in peripheral blood lymphocytes of patients ...
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[188]
Newer ideas about fertility in patients with testicular cancer
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[189]
A perspective on adjuvant chemotherapy of testicular cancer
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[190]
Analysis of serum placental alkaline phosphatase activity in ...
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[191]
Fertility in the testicular cancer patient
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[192]
Complications of primary retroperitoneal lymph-node dissection for ...
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[193]
Testicular cancer and the legacy of chemotherapy
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[194]
Cytoreductive surgery in testicular cancer
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[195]
Vascular and other complications of chemotherapy for testicular cancer
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[196]
Chromosomal abnormalities in sperm from testicular cancer patients ...
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[197]
Testicular Dose in Prostate Cancer Radiotherapy
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[198]
Comparative analysis of different apoptosis detection methods in ...
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[199]
Testicular cancer, occupation and exposure to chemical agents ...
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[200]
Antipyrine metabolism in patients with disseminated testicular ...
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[201]
Maternal Risk Factors for Testicular Cancer: A Population-Based ...
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[202]
Commentary: Combination chemotherapy of nonseminomatous testicular ...
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[203]
The Young Male Experience with Treatment for Nonseminomatous ...
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[204]
Physical activity, medical history, and risk of testicular cancer ...
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[205]
Testicular cancer and electromagnetic fields (EMF) in the ...
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[206]
Birth order and risk of testicular cancer
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[207]
Physical activity and the risk of prostate and testicular cancer ...
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[208]
Unusual neoplasms detected in testicular cancer patients ...
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[209]
Late relapse of testicular cancer
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
[210]
Quality-of-life issues in the treatment of testicular cancer
[19,7 KB]
From [www.springerlink.com] Last viewed: 07.09.2006
testicular
cancer
1581
Testicular Cancer
Sarah J. McAleer
March 5, 2003
Epidemiology
2-3 new cases per 100,000 US males per year
Marked variation in incidence among different countries/races
90-95% are germ cell
Most common solid tumor in males ages 15-35
Risk Factors
Cryptorchidism: 7-10% of patients with testicular cancer have a history of cryptorchidism
Abnormal germ cell morphology
Elevated temperature
Interference with normal blood supply
5-10% of patients with testicular cancer and a history of cryptorchidism develop cancer in the contralateral testis
Orchidopexy does not prevent development of cancer – just allows for detection
Gonadal Dysgenesis ...
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