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TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2002 April/June, Volume 2, Issue 2 133 Effects of Plaferon LB (PLB) on concanavalin A-induced hepatitis in mice Manana Kvezereli*, Tinatin Chikovani*, Tamar Sanikidze**, Rusudan Rukhadze***, Nino Cheishvili*, Tamar Sharashenidze*, Manana Papava**, Vladimer Bakhutashvili* * Institute of Medical Biotechnology, Tbilisi, Georgia ** Scientific-Research Institute of Experimental and Clinical Medicine, Tbilisi,Georgia *** Tbilisi State Medical University, Tbilisi, Georgia Abstract PLB is a mixture of human placental proteins possesing immunomodulatory, antihypoxic and other possibilities. The present study evaluated the effects of PLB on ConA induced hepatitis in mice. Dexamethasone as a control drug was used. After 4 h from ConA injection ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2002 April/June, Volume 2, Issue 2 145 Content of Nitric Oxide in Organs and Tissues and its Importance in Pathogenesis of Alloxan Diabetes David Delibashvili, Vakhtang Kipiani, Manana Namoradze, Zaza Dumbadze Department of Pathological Physiology, Tbilisi State Medical University Abstract Increasing of free radical oxidation and nitrogen oxide synthesis in pancreases, liver and walls of vessels characterize Alloxan diabetes. These processes are generalized and cause the disorders of organs and tissues. Keywords: alloxan diabetes mellitus, nitric Oxide. EPR Introduction uring the recent years of great importance is the function of multifunctional molecule - Nitric Oxide (NO) in the cellular processes of organism at norms and pathology ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2003 January/March, Volume 3, Issue 1 12 The Morphological Changes in Lymph Nodes during Clinical and Experimental Lymphadenopathy of Different Genesis Zaza Avaliani, George Burkadze Department of Pathological Anatomy, Tbilisi State Medical University, Georgia Abstract The study was aimed to compare the most acute, morphologically and clinically diagnosed acute and chronic lymphadenopathy with morphological changes of lymphatic node obtained experimentally. Data obtained have showed that in various stages of the experiments a number of quantitative and structural changes of different regions of the lymphatic nodes with significant deviations of their cellular composition occurred. Similar data, which were observed in clinical cases, appeared to be in certain correlation with ...

TBILISI STATE MEDICAL UNIVERSITY @MM@KR NEAHNLDCHB@KQDRD@QBG@MC DCTB@SHNM 2002 January/March, Volume 2, Issue 1 87 Peculiarities of Immune Response in Infants with Herpes Simplex Virus Infection Eka Uberi*, Manana Zhvania*, Nugzar Uberi*, George Kamkamidze** *Department on Specialization in Pediatrics, Pediatric Clinic of Tbilisi State Medical University **Infectious Diseases, AIDS and Clinical Immunology Research Center Address for Correspondence: Nugzar Uberi Pediatric Clinic of the Tbilisi State Medical University Tel: +(995 32) 22 47 27 Email: eubri@hotmail.com Abstract Herpes Simplex Virus (HSV) infection is one of the most frequent infections in newborns. Main goal of the study was the investigation of peculiarities of immune response to Herpes Simplex Virus infection in newborns. Parameters of humoral and cellular immunity, ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2002 April/June, Volume 2, Issue 2 142 Depression and Social Support in Patients with Exercise - Induced Myocardial Ischemia Nino Chagiashvili, Zurab Pagava, Guram Mamaladze, George Kavtaradze, Tamar Sukhiashvili, Irma Maisuradze Tsinamdzgrishvili Institute of Cardiology, Tbilisi, Georgia Abstract Aim: The evaluation of the importance of depression and social support in patients with exercise - induced myocardial ischemia. Methods and results: We investigated 60 patients, who underwent symptom-limited exercise treadmill ECG testing. The Seattle Angina Questionnaire (SAQ) and Depression Questionnaire (The Center for Epidemiology Studies Depression Scale) were filled by the patients with positive ischemic ECG criteria. 13 patients screened high level of depression. Depressed ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2002 April/June, Volume 2, Issue 2 151 Efficiency of Low Level Laser Therapy in Otology Anna Gogelia Department of Medical Rehabilitation and Sport Medicine at Tbilisi State Medical University Abstract The patients with inflammatory diseases of auditory organ have been treated with Low Level Laser therapy, using "Adept" apparatus. To the patients with inflammation of external auditory meatus Laser Therapy has been used as independent method of treatment and to the patients with acute and chronic otitis media red and infrared irradiation has been carried out simultaneously with traditional therapeutic measures. Doses of Laser therapy have been selected individually, depending on the study of disease, spread of pathologic process and patients' age. Keywords: low ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2003 July/September, Volume 3, Issue 3 Morphological Peculiarities of Periodontal Soft Tissues after Influence of Photo- polymerizing Ionomeric Cement "Perma Flow" Lia Sanodze*, Marina Mamaladze*, Omar Khardzeishvili**, Otar Kevlishvili*** *Stomatological Clinic of Tbilisi State Medical University, The Georgian-German-Spanish Clinic "Unident-Rossi" of Stomatology and Medical Esthetics; **Department of Pathological Anatomy, Tbilisi State Medical University; ***Scientific-Research Institute of Experimental and Clinical Medicine of Tbilisi State Medical University, Georgia Abstract Have been investigated different dental materials for successful filling of perforations with various locations. Among suggested preparations: Dyract (Dentsplay), Ultracal XS, Colapan the Photo-polymerizing ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2003 April/June, Volume 3, Issue 2 Dental Caries in Children with Chronic Tonsillitis George Kipiani, Ketevan Davladze Department of Paedodontic and Stomatologic Disease Prevention, Tbilisi State Medical University, Georgia Abstract Has been detected that in 9 years old children with chronic tonsillitis the clinical course of dental caries and clinical course of active form of dental caries has a strong resemblance, which is confirmed by the relatively increased indices of primary and permanent teeth caries spread and intensity (DMF, df). In children with chronic tonsillitis (29) significant changes in dental plaque microbial ecosystem were detected compared to children with intact tonsils (28). Aforesaid changes first of all were expressed by increased indices of cariogenic microorganisms' ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2003 April/June, Volume 3, Issue 2 Favorable Effects of 24 Hour-Infusion of Magnesium Sulphate in AMI on Early and Long-Term Outcomes of Disease Mamuka Kobalava, Nikoloz Andriadze Scientific-Research Institute of Cardiology, Tbilisi, Georgia Abstract The aim of the study was to evaluate influence of 24 hour-infusion of magnesium sulphate on early and long- term outcomes in patients with Acute Myocardial Infarction (AMI). Patients were divided into two groups. In the study group they received magnesium sulphate in combination with traditional therapy (beta blockers, antiagregants, anticoagulants, nitrates) versus the control group, where patients received only traditional therapy. The favorable clinical effects were mentioned in the study group compared to control resulted in reduction ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2002 April/June, Volume 2, Issue 2 177 Echographic Data of Left Ventricular Morphological Condition in Inflamatory Heart Disease Merab Matiashvili, Manana Zhvania, George Chakhunashvili Department of Pediatrics, Tbilisi State Medical University; Jo Ann Medical center Abstract The important problem is the diagnosis and morphological evaluation of Acute Nonrheumatic Carditis in children. The aim of this trial is to study left ventricle wall morphology with two -dimentional Echocardiography in acute nonrheumatic carditis and the evaluation of the indices both in normal children and with other diseases. More than 222 patients were eximined during this trial which have the diagnosis of acute nonrheumatic carditis. With two-dimentional echocardiography was evaluated the miocardium ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2003 April/June, Volume 3, Issue 2 The Results of Studding Calcilate's Influence in Clinical-Biochemical Status of Human Organism Vera Kapetivadze*, George Grigorashvili**, Sophio Kverenchkhiladze***, Nana Pilia** *Department of Diagnosis internal diseases, Tbilisi State Medical University, Georgia; **G. Natadze S/R Institute of sanitary and hygienic, Georgia; ***Georgian State Medical Academy, Georgia Abstract The tolerance and assimilability of the kalcilate from meat and bone remands contained in the diet in different amounts were studied under clinical condition in 38 males. The clinico-biochemical findings do not indicate kalcilate has an adverse effect on the man. Keywords: calculates, ration of diet, practical feeding, substance changing, biochemical ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2003 July/September, Volume 3, Issue 3 The Nature and the Status of Human Embryo (Ethical Aspects) Bella Mamulashvili Department of Social Studies of Tbilisi State Medical University, Georgia Abstract According to the fundamental scientific knowledge, international organizations and committees in bioethics have adopted ethical norms that prohibit any sort of manipulations upon the human embryo. The origin and formation of the conscious human personality as well as the essence of life have always been stubborn problems for scientists and public opinion. Many a philosophical, religious-theological and psychological concepts has been developed in connection with the above problems. The human embryo bears a special ontological status: The latter is a potential human being. None of the objective ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2003 October/December, Volume 3, Issue 4 Guidelines for Study of Adaptation Processes after Physical Load in Military Personnel Sergo Jaiani*, Naira Chabashvili**, Zurab Kakhabrishvili**, Konstantine Mchedlishvili*, Joseb Dubrovski***, Vitali Kvitas*** *Department of Military Medicine, **Department of Sports Medicine Tbilisi State Medical University, Georgia; ***University of California, San-Francisco, USA ABSTRACT Have been studied the processes of adaptation in representatives of military forces after physical loads and elaborated methodical recommendations. Experiments have been carried out on students of faculty of military medicine under the normal load conditions. The results of investigation have shown that owing to arterial pressure and pulse rate monitoring it is possible ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2003 April/June, Volume 3, Issue 2 Pro- and Antioxidant Systems' Changes of Blood in Patients with Diabetic Angiopathy Nika Navadze, Ivane Datunashvili Department of Surgery, Tbilisi State Medical University, Georgia Abstract It is known that in the pathogenesis of development of diabetic angiopathy the big role plays free radical interrelations. That is why we studied Pro- and antioxidant systems' changes of blood in patients with diabetic angiopathy before and after traditional treatment by the method of the electro paramagnetic resonance. The received results show that in investigated patients' blood was supervised the surplus of free-radical interrelations on the background of the law activity of anti-oxidant protection enzymes. The level of NO is law in blood which is provoked ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2003 July/September, Volume 3, Issue 3 Standardization and adaptation of the Denver Developmental Screening Test (DDST) for use in Tbilisi children Gocha Chikvinidze*, Nana Geladze*, George Natriashvili,* Zurab Tsigroshvili** * Tbilisi State Medical University Pediatric Clinic Department of Pediatric Neurology **Georgian Academy of Science A. Razmadze Mathematical Institute, Tbilisi, Georgia Abstract Objective - To modify and standardize the Denver Developmental Screening Test (DDST) for developmental screening of children in Tbilisi. Method - The study used a quota sample of 1006 Children of Tbilisi, aged 16 days to 6 years. The study protocol was based on the DDST. The Logistic Regression Analysis established the 25th, 50th, 75th and 90th percentile passing age for achieving ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2003 October/December, Volume 3, Issue 4 "Trovex" in the Treatment of Microsporia Alexander Katsitadze, Nathalie Kiladze, Zurab Bendeliani, Nino Tsiskarishvili, Gaioz Pagava Department of Dermatology and Venerology, Tbilisi State Medical University, Georgia ABSTRACT The goal of present study was to evaluate the therapeutic efficiency of Georgian produced drug "Trovex" (terbinafine) manufactured by Pharmimpex LTD, in the treatment of Microsporia. The study included 10 patients in the age of 5- 10 years old with Microsporia of scalp and smooth skin, all infected from pets. In all cases the diagnosis was confirmed by direct microscopy of scrapings and with the use of Wood's light. All patients were treated by "Trovex" orally with the dose of 125 mg once a day. The course of treatment varied ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2003 October/December, Volume 3, Issue 4 Peculiarities of Epileptic Seizure as Early Symptom of Cerebrovascular Disease in Refugees from Abkhazia Nino Ninua, Nick Malashkhia Department of Neurology, Tbilisi State Medical University, Georgia ABSTRACT The aim of our study was to evaluate the peculiarities of epileptic seizure as early manifestation of cerebrovascular disease in refugees. 2210 refugees were evaluated in Tbilisi State Medical University Central clinical Hospital Neurology Department, and Outpatient Department. Man - 965 (43,6%), Woman - 1245 (56,4%). We revealed early symptoms of cerebrovascular disease in 440 cases among 2210 refugees based on anamnetic questionnaires. 46 patients had 2 or less epileptic seizures in the last 1year period. Among them 38 patients revealed ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2003 January/March, Volume 3, Issue 1 27 Forecasting of Local Intraoperative Complications of Hip Joint Endoprosthetics during Dysplastic Coxarthrosis Tornike Nozadze, Tamaz Katsitadze Orthopedic Clinic "Sintezi", Tbilisi, Georgia Abstract Has been carried out multi-dimensional statistical analysis of intraoperative complications of hip joint endoprosthetics on the basis of 129 patients with dysplastic coxarthrosis. Using regressive analysis, predictors of following intraoperative complications - nerve overstretching and fracture of diaphysis have been established. Results of investigation could be used during planning of operations in order to reveal the risk groups and prevent complications during endoprosthetics. Keywords: dysplastic coxarthrosis, endoprosthetics, ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2002 October/December, Volume 2, Issue 4 38 The Influence of Early Seizure Control on Outcome of Cerebral Palsy Maia Gabunia, Ekaterine Arveladze, Lia Kandareli, Nino Tatishvili, Khatuna Davituliani Center for Child Neurology and Neurorehabilitation, Tbilisi State Medical University, Georgia Abstract The aim of the study was evaluation of influence of quality of epilepsy care on long-term outcome of patients with cerebral palsy (CP). In patients with CP and epilepsy, accurate clinical and EEG investigation with early identification of seizure type and epilepsy syndrome, adequate treatment and EEG follow-up during physical therapy results in higher rate of seizure control, increases possibility of realization of monotherapy and continuous physical therapy which in turn significantly ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2003 January/March, Volume 3, Issue 1 61 The Principles of Medical Ethics In Healthcare of Georgia Nino Chikhladze, Malkhaz Kereselidze Medical-Diagnostic Center N 1, Tbilisi, Georgia Abstract The article deals with the significance of principles of medical ethics in the healthcare of Georgia, which is deeply rooted in the historical past of Georgia. It also throws some light on the philanthropy in the activities of some Georgian doctors and medical communities in the XIX-XX centuries. Keywords: healthcare, medical ethics, history of medicine he system of healthcare in Georgia was laid foundation in the 19th century, though the principles of medical ethics and deontology are deeply rooted in the historical past of Georgia. In the 19th century Georgian ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2002 October/December, Volume 2, Issue 4 22 Comparison Of The Reliability Of Computerized And Manual Cephalometric Measurements Of Soft Tissue Tamar Kublashvili, Katerin Kula, Alan Glaros, Zurab Vadachkoria UMKC School of Dentistry Department of Orthodontics, USA; Department of Pediatric and Prevention of Dental Diseases, Tbilisi State Medical University, Georgia Abstract The purpose of this study was to compare the reliability of eleven linear and four angular cephalometric measurements of soft tissue among two software programs (Dolphin 7.0 [D] and Vistadent 8.0 [V]) using both digitized (scanned) conventional films and digital radiography when compared to manual tracings. The cephalometric images were captured simultaneously for each research subject by placing ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2003 January/March, Volume 3, Issue 1 54 Innovations in Differential Diagnosis of Dystrophic-Degenerative Diseases of Vertebral Column Nino Ninua, Ivane Verulashvili, Manana Gordeziani, Ia Rukchadze Department of Neurology, Tbilisi State Medical University, Georgia Abstract Data of paraclinical research (convential roentgenography, CT, MRI, CT + myelography) of 98 patients with the dystrophic-degenerative diseases of vertebral column's lumbar region revealed the main reasons of back pain syndrome: the herniation of intervertebral discs (52 patients), spinal stenosis + osteofits (25 patients), spinal stenosis + ligamental hyperthrophy and annulus fibrosus (21 patients). Neuroimaging complex investigation is out of discussion when spinal cord's and vertebral column's different ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2003 January/March, Volume 3, Issue 1 30 Serotyping of Georgian Strains of H.pylori Based on Cytotoxin Producing Features (CagA and VacA) and the Role of Different Serotypes in the Development of Surgical Complications and Various Clinical Outcomes of PUD Levan Labauri *, Nodar Lomidze *, Darejan Chikviladze **, Manana Lobjanidze **, Merab Buadze ***, Tina Kutubidze ***, Perez-Perez Guillermo Ignacio**** *#1 Department of Surgery, **Department of Microbiology, Virology and Immunology at Tbilisi State Medical University, Georgia; ***Pediatric Hospital of Tbilisi State Medical University, Georgia; **** Section of Medical Microbiology, Division of Infectious Diseases, New York University School of Medicine, USA Address for Correspondence : Dr. Levan ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2003 January/March, Volume 3, Issue 1 35 Influence of the "Free-Radical-Antiradical Activity" System on the Level of Bronchial Obstruction in Patients with Chronic Obstructive Bronchitis, Complicated with Chronic Pulmonary Insufficiency George Kalandarishvili, George Gurgenidze, Marina Janjgava, Mzia Gzirishvili, Medea Gegia, Vaja Gvantseladze Department of Diagnosis and Therapy of Internal Diseases, Tbilisi State Medical University, Georgia Abstract Have been stated, that parameters of free radicals and a degree of imbalance in system - "free radicals - antiradical activity" statistically correlates with chronic obstructive bronchitis and chronic lung insufficiency. Keywords: COPD, hypoxia, free radicals, pulmonary insufficiency, spirometry ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2003 October/December, Volume 3, Issue 4 Evaluation of Clinical Results after Surgical Treatment of The Varicose veins of Lower Limbs Zaza Lazarashvili, Marika Petriashvili, David Chigitashvili Department of Surgery #1, Tbilisi State Medical University, Georgia ABSTRACT Stripping is the standard surgical treatment method in case of lower limb varicose veins however, universal transplant material for arterial reconstructions, as v. saphena magna , loses. In this study various organ- sparing methods of surgical treatment are suggested, however their efficiency is not completely detected yet. The present work was aimed to compare the clinical results of stripping and CHIVA-surgery. A total of 178 operated limbs (stripping - 62 and CHIVA-surgery - 116) have been investigated. Preoperative diagnostics ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2003 April/June, Volume 3, Issue 2 Some Molecular Mechanisms of Different Stress Factors Influence on Process of Physiological Pregnancy David Gagua, Jaba Gamrekelashvili, Nikoloz Kintraia Department of Obstetric and Gynecology, Tbilisi State Medical University, Georgia Abstract As it is known in case of complications at pregnancy, homeostasis is disturbed, takes place hypoxia, intensification of oxidative process, changes in NO metabolism, often having undesirable effect as on mother organism as well as on fetus. Due to the above-mentioned the aim of our study is the investigation of free radical oxidation and NO metabolism processes during the influence of different stress factors on body at the experiment. It can be concluded that antioxidative system of blood is very sensible ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2002 October/December, Volume 2, Issue 4 312 Specific Prevalence of Tumor-like Bone Lesions in Children Marina Gudushauri, Ramaz Chikhladze Department of Pathology Tbilisi State Medical University Abstract Analyses of the 1981-2000 data for the prevalence of childhood tumor-like bone lesions in Georgia in relation to the age and sex of the patients revealed that the most frequent forms of pathology were bone cyst, fibrous displasia, and non-osteogenic fibroma, with the ratio of 6:2:1. These pathologies were found in boys twice as often as in girls. Patients with bone cyst were, as a rule, younger than those with fibrous displasia and non- osteogenic fibroma. All mentioned above reflects the specificity of tumor-like bone lesion prevalence in children in Georgia. Key words: ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2002 January/March, Volume 2, Issue 1 5 Immunal Status EPH in Conditions of Gestosis of Women Living in Different Regions of Georgia Levan Bezhanidze Obstetrics-Gynecology and perinotology C\R Institute of Ministry of Public Health Of Georgia; Batumi Maternity House Abstract The phenotypic and morphological peculiarities of immunocompetentive cells of peripheral blood in women having toxicosis in the II half of pregnancy living in Tbilisi and Batumi have been studied by the authors. The authors suppose that the immunological changes exposed during the mentioned pathology may be the basis of the disorders of "immunological recognition and cooperation" processes. Keywords: pregnancy, gestosis, immunology, mononuclear cells or the present moment more data appear ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2002 July/September, Volume 2, Issue 3 255 Barriers to Establishing Healthy Lifestyle Habits in Young Generation of Georgia Vephkhvia Odisharia Department of Social Health Care and Management, Tbilisi State Medical University Abstract Under the existing conditions, preventive medicine is inhibited by the socio-economic status, the insufficiency of the state finance, the problems of organization, including treatments connected the mode of the human life. Composite socio-hygienic research correlated the connection between treatments in the young population and public-political, socio-economic, moral-psychological stresses. Sharp growth of young alcoholism, drug addicts, traumas, infectious diseases, tuberculosis reflect insufficiency of the preventive and propaganda measures ...

TBILISI STATE MEDICAL UNIVERSITY ANNALS OF BIOMEDICAL RESEARCH AND EDUCATION 2003 April/June, Volume 3, Issue 2 Surgical Treatment of Parodontitis by "Bio-Oss", Combination of "Bio-Oss" and Recombinant Human Bone Morphogenetic Protein-2 (rhBMP-2) and Evaluation of Obtained Results by Osteometric Method Zurab Orjonikidze Dentistry Clinic of Tbilisi State Medical University, Department of Surgical Stomatology, Tbilisi, Georgia Abstract The aim of our study was the evaluation of obtained results after surgical treatment with Bio-Oss (group II) and complex application of Bio-Oss and recombinant human bone morphogenetic protein-2 (group III) by osteometric method. Analyses of obtained results shows that Bio-Oss and rhBMP-2 represent the modern technologies that could be used for acceleration of bone tissue regeneration. Combination of Bio-Oss and ...